Journal ArticleDOI
Hepatoprotective potential of Fumaria indica Pugsley whole plant extracts, fractions and an isolated alkaloid protopine.
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TLDR
The present investigation demonstrates the hepatoprotective potential of 50% ethanolic water extract of whole plant of Fumaria indica and its three fractions viz., hexane, chloroform and butanol against d-galactosamine induced hepatotoxicity in rats.About:
This article is published in Phytomedicine.The article was published on 2008-06-20. It has received 84 citations till now. The article focuses on the topics: Protopine & Fumaria.read more
Citations
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A Review on Hepatoprotective Activity of Medicinal Plants
TL;DR: The present review is aimed at compiling data on promising phytochemicals from medicinal plants that have been tested in hepatotoxicity models using modern scientific system.
Book
Chromatographic fingerprint analysis of herbal medicines : thin-layer and high performance liquid chromatography of Chinese drugs
TL;DR: This manual, to be published in two volumes, provides a condensed overview of the analytical investigation of 80 Chinese Herbal Drugs which are most frequently in use to meet the standard of the European Drug Regulatory Authority.
Antioxidant activities and phenolic compounds in Bulgarian Fumaria species
Ivan Ivanov,Radka Vrancheva,Andrey S. Marchev,Nadezhda Petkova,Panteley Denev,Vasil Georgiev,Atanas Pavlov +6 more
TL;DR: In this article, the Bulgarian Academy of Science has proposed a method to improve the performance of the Bulgarian National Institute for Viticulture and Small Fruit Research (Bulgarian National Institute of Viticulture, Small Fruit, and Fruit Research).
Journal ArticleDOI
Antioxidant and hepatoprotective activity appraisal of four selected Fumaria species and their total phenol and flavonoid quantities.
TL;DR: The data revealed that the chloroform and ethyl acetate fractions of F. cilicica did not have hepatoprotective effect and the ethanol extracts exerted low antioxidant activity.
Journal ArticleDOI
Protopine Protects Mice against LPS-Induced Acute Kidney Injury by Inhibiting Apoptosis and Inflammation via the TLR4 Signaling Pathway
Beibei Zhang,Mengnan Zeng,Meng Li,Yuxuan Kan,Benke Li,Ruiqi Xu,Yuanyuan Wu,Shengchao Wang,Xiaoke Zheng,Weisheng Feng +9 more
TL;DR: The protopine isolated from C. humosa Migo protected mice against LPS-induced AKI by inhibiting apoptosis and inflammation via the TLR4 signaling pathway, thus providing a molecular basis for a novel medical treatment of AKI.
References
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Journal ArticleDOI
Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
TL;DR: Using this method, the liped peroxide level in the liver of rats suffering from carbon tetrachloride intoxication was investigated and was in good agreement with previously reported data obtained by measuring diene content.
Journal ArticleDOI
Tissue sulfhydryl groups
TL;DR: A water-soluble (at pH 8) aromatic disulfide [5,5′-dithiobis(2-nitrobenzoic acid] has been synthesized and shown to be useful for determination of sulfhydryl groups.
Journal ArticleDOI
A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.
Stanley Reitman,Sam Frankel +1 more
Journal ArticleDOI
Ethical guidelines for investigations of experimental pain in conscious animals.
TL;DR: The Committee for Research and Ethical Issues of the International Association for the Study of Pain (IASP®) is concerned with the ethical aspects of studies producing experimental pain and any suffering it may cause in animals.
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K.S Rao,Shri Hari Mishra +1 more