Journal ArticleDOI
Heterocyclen aus CH-aciden Nitrilen, VIII. 2-Amino-thiophene aus methylenaktiven Nitrilen, Carbonylverbindungen und Schwefel
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In this paper, the Einwirkung von Schwefel auf vinyloge methylenaktive Nitrile, gestattet auch die Einbeziehung von Alkylarylketonen in die Reaktion.Abstract:
Aliphatische Ketone, Aldehyde sowie β-Dicarbonylverbindungen reagieren mit methylenaktiven Nitrilen und Schwefel in Gegenwart von Aminen bei Raumtemperatur zu 2-Aminothiophenen. — Eine Variante der Synthese, die Einwirkung von Schwefel auf vinyloge methylenaktive Nitrile, gestattet auch die Einbeziehung von Alkylarylketonen in die Reaktion.read more
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Thieno(2,3-d)Pyrimidine-4-Ones. Part 5.# Hydrogen Chloride Promoted Synthesis of 2-Substituted Thieno(2,3-d)Pyrimidine-4-Ones and their Structural Investigations
TL;DR: In this paper, the synthesis of 2-substituted thieno[2,3d]pyrimidine-4-ones has been studied and the structure of synthesized compounds was confirmed by IR- and IR-and IR-based methods.
Simple and Efficient Synthesis of Novel Glycosyl Thiourea Derivatives Derived from Thiophene as Potential Antitumor Agents
TL;DR: The practical synthesis of pseudonucleosides incorporating thiourea derivative by coupling of monosaccharides (D-glucose and D-galactose) per-O-acetylated glycosyl isothiocyanates and different heterocyclic hydrazide derivatives is reported.
Journal Article
In vitro Biological Activity of Some Synthesized Monoazo Heterocycles Based On Thiophene and Thiazolyl-Thiophene Analogues
M. E. Khalifa,A. A. Gobouri +1 more
TL;DR: Two series of 2-Aminothiazole and 3-amino-4arylazothiophene derivatives displaying remarkable activities against selected pathogenic microorganisms are reported.
Journal ArticleDOI
2-Ethyl 4-methyl 5-amino-3-methylthiophene-2,4-dicarboxylate
TL;DR: In this paper, a mixture contaning ethyl acetoacetate (13.02 g, 0.1 mol), methyl cyanoacetate, methyl sulfate, and sulfur was added to a mixture of 20 ml ethanol and morpholine.
Journal ArticleDOI
Synthesis of mono- and dibromomethyl derivatives of thieno[2,3-d] pyrimidines
N. V. Kaplina,A. N. Grinev,G. A. Bogdanova,L. M. Alekseeva,T. V. Pushkina,A. N. Fomina,V. I. Shvedov +6 more
TL;DR: In this paper, the bromination of 4-chloroand 4-methoxythieno[2,3-d]pyrimidines with no substituents at the 5 and 6 positions was studied.
References
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Heterocyclen aus CH-aciden Nitrilen, VII. 2-Amino-thiophene aus α-Oxo-mercaptanen und methylenaktiven Nitrilen
TL;DR: In this paper, the α-Oxo-mercaptane reagieren mit Nitrilen, die in α-Stellung eine aktive Methylengruppe besitzen, basenkatalysiert zu 2.3.
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