Journal ArticleDOI
Heterocyclen aus CH-aciden Nitrilen, VIII. 2-Amino-thiophene aus methylenaktiven Nitrilen, Carbonylverbindungen und Schwefel
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TLDR
In this paper, the Einwirkung von Schwefel auf vinyloge methylenaktive Nitrile, gestattet auch die Einbeziehung von Alkylarylketonen in die Reaktion.Abstract:
Aliphatische Ketone, Aldehyde sowie β-Dicarbonylverbindungen reagieren mit methylenaktiven Nitrilen und Schwefel in Gegenwart von Aminen bei Raumtemperatur zu 2-Aminothiophenen. — Eine Variante der Synthese, die Einwirkung von Schwefel auf vinyloge methylenaktive Nitrile, gestattet auch die Einbeziehung von Alkylarylketonen in die Reaktion.read more
Citations
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First Synthesis of Phosphorylated Thienopyridines from 2-amino-3-cyanothiophenes and β-ketophosphonates
Khaoula Khalladi,Soufiane Touil +1 more
TL;DR: In this paper, treatment of 2-amino-3-cyanothiophenes with β-ketophosphonates, under acid catalysis, leads to new 4-AMino-5-phosphonothieno[2,3-b]pyridines in good to excellent yields.
Journal ArticleDOI
Synthesis, evaluation and modeling of some triazolothienopyrimidinones as anti-inflammatory and antimicrobial agents.
Adnan A. Bekhit,Ahmed M. Farghaly,R. M. Shafik,Mona M. El-Semary,Mai S. El-Shoukrofy,Alaa El-Din A. Bekhit,Tamer M. Ibrahim,Tamer M. Ibrahim +7 more
TL;DR: This work represents a promising matrix for developing new potential anti-inflammatory, antimicrobial and dual antimicrobial/anti-inflammatory candidates.
Journal ArticleDOI
Neue Derivate der 2-Acylamino-thiophen-(und-benzo[b]thiophen-)-3-carbonsäure sowie des ([1]Benzo-)Thieno[2,3-d]-pyrimidin-4(3H)-ons
TL;DR: In this article, the title substances were prepared by acylation of the corresponding ethyl 2-amino-thiophene-3-carboxylates, in some cases followed by reactions introducing a basic substituent.
Journal ArticleDOI
Neue Synthese von substituierten 4-Amino-chinazolinen und deren Heteroanalogen
TL;DR: In this article, the synthesis of substituted 4-Amino-quinazolines and their Heteroanaloga (HOA) derivatives is described. But the synthesis conditions are not specified.
Journal ArticleDOI
Utility of 2-Aminothiophene-3-carboxamide in the Synthesis of Biologically Active, Fused Heterocyclic Derivatives
TL;DR: In this article, the in vitro antimicrobial activity of newly synthesized compounds against bacteria was studied, and the results showed that the new compounds showed promising antimicrobial properties against bacteria.
References
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Journal ArticleDOI
Heterocyclen aus CH-aciden Nitrilen, VII. 2-Amino-thiophene aus α-Oxo-mercaptanen und methylenaktiven Nitrilen
TL;DR: In this paper, the α-Oxo-mercaptane reagieren mit Nitrilen, die in α-Stellung eine aktive Methylengruppe besitzen, basenkatalysiert zu 2.3.
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