Journal ArticleDOI
How is our self related to midline regions and the default-mode network?
Pengmin Qin,Georg Northoff +1 more
TLDR
The data suggest that the sense of self may result from a specific kind of interaction between resting state activity and stimulus-induced activity, i.e., rest-stimulus interaction, within the midline regions.Citations
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BOLD signal and functional connectivity associated with loving kindness meditation.
TL;DR: Functional magnetic resonance imaging is used to assess the neural substrate of loving kindness meditation in experienced meditators and novices and suggests group differences in brain regions involved in self‐related processing and mind wandering, emotional processing, inner speech, and memory.
Journal ArticleDOI
The Amygdala in Schizophrenia and Bipolar Disorder: A Synthesis of Structural MRI, Diffusion Tensor Imaging, and Resting-State Functional Connectivity Findings.
TL;DR: Future studies can consider adopting longitudinal approaches with multimodal imaging and more extensive clinical subtyping to probe amygdalar subregional changes and their relationship to the sequelae of psychotic disorders.
Journal ArticleDOI
Psychedelics and the science of self-experience
TL;DR: A neuroscience of self-experience has begun to crystallise, drawing upon findings from functional neuroimaging and altered states of consciousness occasioned by psychedelic drugs, of great importance for psychiatry.
Journal ArticleDOI
Neural correlates of self-focused attention in social anxiety
TL;DR: Results highlight the prominent role of the mPFC and other cortical structures in abnormal self-focused attention in social anxiety, and findings for the insula suggest increased processing of bodily states that is related to the amount of habitual self- focused attention inSocial anxiety.
Journal ArticleDOI
The Human Ventromedial Prefrontal Cortex: Sulcal Morphology and Its Influence on Functional Organization.
TL;DR: It is shown that two supplementary medial sulci predominantly determine the organization of the vmPFC, which in turn affects the location of the functional peak of activity in this region, which shows that taking into account the variability in sulcal patterns might be essential to guide the interpretation of neuroimaging studies of the human brain and of thevmPFC in particular.
References
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Journal ArticleDOI
A default mode of brain function.
Marcus E. Raichle,Ann Mary MacLeod,Abraham Z. Snyder,William J. Powers,Debra A. Gusnard,Gordon L. Shulman +5 more
TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
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AFNI: software for analysis and visualization of functional magnetic resonance neuroimages
TL;DR: A package of computer programs for analysis and visualization of three-dimensional human brain functional magnetic resonance imaging (FMRI) results is described and techniques for automatically generating transformed functional data sets from manually labeled anatomical data sets are described.
Journal ArticleDOI
The Brain's Default Network Anatomy, Function, and Relevance to Disease
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.
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The human brain is intrinsically organized into dynamic, anticorrelated functional networks
Michael D. Fox,Abraham Z. Snyder,Justin L. Vincent,Maurizio Corbetta,David C. Van Essen,Marcus E. Raichle +5 more
TL;DR: It is suggested that both task-driven neuronal responses and behavior are reflections of this dynamic, ongoing, functional organization of the brain, featuring the presence of anticorrelated networks in the absence of overt task performance.
Journal ArticleDOI
Functional connectivity in the resting brain: A network analysis of the default mode hypothesis
TL;DR: This study constitutes, to the knowledge, the first resting-state connectivity analysis of the default mode and provides the most compelling evidence to date for the existence of a cohesive default mode network.