Journal ArticleDOI
How is our self related to midline regions and the default-mode network?
Pengmin Qin,Georg Northoff +1 more
TLDR
The data suggest that the sense of self may result from a specific kind of interaction between resting state activity and stimulus-induced activity, i.e., rest-stimulus interaction, within the midline regions.Citations
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Restructuring consciousness -the psychedelic state in light of integrated information theory
TL;DR: This model suggests that whilst cognitive flexibility, creativity, and imagination are enhanced during the psychedelic state, this occurs at the expense of cause-effect information, as well as degrading the brain's ability to organize, categorize, and differentiate the constituents of conscious experience.
Journal ArticleDOI
Modulation of brain response to emotional conflict as a function of current mood in bipolar disorder: preliminary findings from a follow-up state-based fMRI study.
Gwladys Rey,Martin Desseilles,Sophie Favre,Alexandre Dayer,Camille Piguet,Jean-Michel Aubry,Patrik Vuilleumier +6 more
TL;DR: The results indicate that the ability of BD patients to recruit control networks when processing affective conflict, and the abnormal suppression of activity in distinct components of the default mode network, may depend on their current clinical state and attentional demand.
Journal ArticleDOI
Pubertal maturation and sex effects on the default-mode network connectivity implicated in mood dysregulation
Monique Ernst,Brenda E. Benson,Eric Artiges,Adam X. Gorka,Herve Lemaitre,Tiffany R. Lago,Ruben Miranda,Tobias Banaschewski,Arun L.W. Bokde,Uli Bromberg,Rüdiger Brühl,Christian Büchel,Anna Cattrell,Patricia J. Conrod,Patricia J. Conrod,Sylvane Desrivières,Tahmine Fadai,Herta Flor,Herta Flor,Antoine Grigis,Juergen Gallinat,Hugh Garavan,Penny A. Gowland,Yvonne Grimmer,Andreas Heinz,Viola Kappel,Frauke Nees,Frauke Nees,Dimitri Papadopoulos-Orfanos,Jani Penttilä,Luise Poustka,Luise Poustka,Michael N. Smolka,Argyris Stringaris,Argyris Stringaris,Maren Struve,Betteke van Noort,Henrik Walter,Robert Whelan,Gunter Schumann,Christian Grillon,Marie-Laure Paillère Martinot,Jean-Luc Martinot +42 more
TL;DR: Stronger iFC of the anterior DMN may signal disconnections among circuits supporting mood regulation, conferring risk for internalizing disorders, according to the Triple-Network Model.
Journal ArticleDOI
Dissociable roles of default-mode regions during episodic encoding.
David Maillet,M. Natasha Rajah +1 more
TL;DR: It is concluded that DMN regions play dissociable roles during memory formation, and that their association with subsequent memory may depend on the manner in which information is encoded and retrieved.
Journal ArticleDOI
Distinct neural bases of disruptive behavior and autism symptom severity in boys with autism spectrum disorder
Y.J. Daniel Yang,Y.J. Daniel Yang,Denis G. Sukhodolsky,Jiedi Lei,Jiedi Lei,Eran Dayan,Kevin A. Pelphrey,Pamela Ventola +7 more
TL;DR: In boys with ASD, disruptive behavior has a neural basis in reduced DMN deactivation, which is distinct and separable from that of core ASD symptoms, with the latter characterized by hypoactivation in the social perception circuitry.
References
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Journal ArticleDOI
A default mode of brain function.
Marcus E. Raichle,Ann Mary MacLeod,Abraham Z. Snyder,William J. Powers,Debra A. Gusnard,Gordon L. Shulman +5 more
TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
Journal ArticleDOI
AFNI: software for analysis and visualization of functional magnetic resonance neuroimages
TL;DR: A package of computer programs for analysis and visualization of three-dimensional human brain functional magnetic resonance imaging (FMRI) results is described and techniques for automatically generating transformed functional data sets from manually labeled anatomical data sets are described.
Journal ArticleDOI
The Brain's Default Network Anatomy, Function, and Relevance to Disease
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.
Journal ArticleDOI
The human brain is intrinsically organized into dynamic, anticorrelated functional networks
Michael D. Fox,Abraham Z. Snyder,Justin L. Vincent,Maurizio Corbetta,David C. Van Essen,Marcus E. Raichle +5 more
TL;DR: It is suggested that both task-driven neuronal responses and behavior are reflections of this dynamic, ongoing, functional organization of the brain, featuring the presence of anticorrelated networks in the absence of overt task performance.
Journal ArticleDOI
Functional connectivity in the resting brain: A network analysis of the default mode hypothesis
TL;DR: This study constitutes, to the knowledge, the first resting-state connectivity analysis of the default mode and provides the most compelling evidence to date for the existence of a cohesive default mode network.