Journal ArticleDOI
How is our self related to midline regions and the default-mode network?
Pengmin Qin,Georg Northoff +1 more
TLDR
The data suggest that the sense of self may result from a specific kind of interaction between resting state activity and stimulus-induced activity, i.e., rest-stimulus interaction, within the midline regions.Citations
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Book ChapterDOI
The Default Network and Social Cognition
TL;DR: The default network as discussed by the authors is a neurocognitive network implicated in social cognition and other forms of self-generated thought, and the topology of the default network, delineated using resting-state functional connectivity MRI, includes core regions and two distinct subsystems.
Journal ArticleDOI
Major histocompatibility complex peptide ligands as olfactory cues in human body odour assessment
TL;DR: The results suggest that despite the absence of a vomeronasal organ, humans have the ability to detect and evaluate MHC peptides in body odour, which may provide a basis for the sensory evaluation of potential partners during human mate choice.
Journal ArticleDOI
Brains creating stories of selves: the neural basis of autobiographical reasoning
Arnaud D'Argembeau,Helena Cassol,Christophe Phillips,Evelyne Balteau,Eric Salmon,Martial Van der Linden +5 more
TL;DR: The notion that autobiographical reasoning and the construction of personal narratives go beyond mere remembering in that they require deriving meaning and value from past experiences is supported.
Journal ArticleDOI
Effects of Ketamine on Resting-State EEG Activity and Their Relationship to Perceptual/Dissociative Symptoms in Healthy Humans.
Joelle Choueiry,Dhrasti Shah,Hayley Bowers,Judy McIntosh,Vadim Ilivitsky,Vadim Ilivitsky,Verner Knott +6 more
TL;DR: The hypothesis that pathological brain oscillations associated with hypofunctional NMDA receptor activity may contribute to the emergence of the perceptual/dissociate symptoms of schizophrenia is tentatively supported.
Journal ArticleDOI
Default mode network as a potential biomarker of chemotherapy-related brain injury.
TL;DR: Default mode network (DMN) is a strong candidate considering its preferential vulnerability to aging and sensitivity to toxicity and disease states and biomarkers of DMN connectivity could aid in the development of treatments for chemotherapy-related cognitive decline.
References
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Journal ArticleDOI
A default mode of brain function.
Marcus E. Raichle,Ann Mary MacLeod,Abraham Z. Snyder,William J. Powers,Debra A. Gusnard,Gordon L. Shulman +5 more
TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
Journal ArticleDOI
AFNI: software for analysis and visualization of functional magnetic resonance neuroimages
TL;DR: A package of computer programs for analysis and visualization of three-dimensional human brain functional magnetic resonance imaging (FMRI) results is described and techniques for automatically generating transformed functional data sets from manually labeled anatomical data sets are described.
Journal ArticleDOI
The Brain's Default Network Anatomy, Function, and Relevance to Disease
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.
Journal ArticleDOI
The human brain is intrinsically organized into dynamic, anticorrelated functional networks
Michael D. Fox,Abraham Z. Snyder,Justin L. Vincent,Maurizio Corbetta,David C. Van Essen,Marcus E. Raichle +5 more
TL;DR: It is suggested that both task-driven neuronal responses and behavior are reflections of this dynamic, ongoing, functional organization of the brain, featuring the presence of anticorrelated networks in the absence of overt task performance.
Journal ArticleDOI
Functional connectivity in the resting brain: A network analysis of the default mode hypothesis
TL;DR: This study constitutes, to the knowledge, the first resting-state connectivity analysis of the default mode and provides the most compelling evidence to date for the existence of a cohesive default mode network.