Journal ArticleDOI
How is our self related to midline regions and the default-mode network?
Pengmin Qin,Georg Northoff +1 more
TLDR
The data suggest that the sense of self may result from a specific kind of interaction between resting state activity and stimulus-induced activity, i.e., rest-stimulus interaction, within the midline regions.Citations
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Journal ArticleDOI
Self, cortical midline structures and the resting state: Implications for Alzheimer's disease.
TL;DR: Not only episodic (and autobiographical memory) impairment in patients, but also the important role of cortical midline structures, the Default Mode Network, and the resting state for the processing of self-related information is described.
Journal ArticleDOI
The self-reference effect in dementia: Differential involvement of cortical midline structures in Alzheimer's disease and behavioural-variant frontotemporal dementia.
Stephanie Wong,Muireann Irish,Eric D. Leshikar,Audrey Duarte,Maxime Bertoux,Greg Savage,John R. Hodges,Olivier Piguet,Michael Hornberger +8 more
TL;DR: The imaging findings revealed that reductions in the SRE were associated with atrophy in the anterior-dorsal CMS across both patient groups, with additional involvement of the posterior CMS in AD and anterior-ventral CMS in bvFTD.
Journal ArticleDOI
The sense of self in the aftermath of trauma: lessons from the default mode network in posttraumatic stress disorder
Ruth A. Lanius,Ruth A. Lanius,Braeden A. Terpou,Margaret C. McKinnon,Margaret C. McKinnon,Margaret C. McKinnon +5 more
TL;DR: DMN-related alterations during rest and during subliminal, trauma-related stimulus conditions are discussed, pointing further towards the clinical significance of these findings in relation to past- and present-centred therapies for the treatment of PTSD.
Journal ArticleDOI
Neural responses to heartbeats distinguish self from other during imagination.
TL;DR: Heartbeat‐evoked responses appear as a neural marker distinguishing self from other during imagination, and could be a mechanism for self/other distinction.
Book ChapterDOI
Meditation Effects in the Social Domain: Self-Other Connectedness as a General Mechanism?
TL;DR: In this article, the authors examined self and other from the perspective of psychology and neuroscience, integrating findings from these fields into a dimension of mental functioning anchored to self-centeredness and self-other-connectedness, respectively.
References
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Journal ArticleDOI
A default mode of brain function.
Marcus E. Raichle,Ann Mary MacLeod,Abraham Z. Snyder,William J. Powers,Debra A. Gusnard,Gordon L. Shulman +5 more
TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
Journal ArticleDOI
AFNI: software for analysis and visualization of functional magnetic resonance neuroimages
TL;DR: A package of computer programs for analysis and visualization of three-dimensional human brain functional magnetic resonance imaging (FMRI) results is described and techniques for automatically generating transformed functional data sets from manually labeled anatomical data sets are described.
Journal ArticleDOI
The Brain's Default Network Anatomy, Function, and Relevance to Disease
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.
Journal ArticleDOI
The human brain is intrinsically organized into dynamic, anticorrelated functional networks
Michael D. Fox,Abraham Z. Snyder,Justin L. Vincent,Maurizio Corbetta,David C. Van Essen,Marcus E. Raichle +5 more
TL;DR: It is suggested that both task-driven neuronal responses and behavior are reflections of this dynamic, ongoing, functional organization of the brain, featuring the presence of anticorrelated networks in the absence of overt task performance.
Journal ArticleDOI
Functional connectivity in the resting brain: A network analysis of the default mode hypothesis
TL;DR: This study constitutes, to the knowledge, the first resting-state connectivity analysis of the default mode and provides the most compelling evidence to date for the existence of a cohesive default mode network.