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Journal ArticleDOI

How is our self related to midline regions and the default-mode network?

Pengmin Qin, +1 more
- 01 Aug 2011 - 
- Vol. 57, Iss: 3, pp 1221-1233
TLDR
The data suggest that the sense of self may result from a specific kind of interaction between resting state activity and stimulus-induced activity, i.e., rest-stimulus interaction, within the midline regions.
Citations
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Journal ArticleDOI

Is the cardiac monitoring function related to the self in both the default network and right anterior insula

TL;DR: It is proposed that a common mechanism, the neural monitoring of cardiac signals, underlies the self in both the DN and rAI, which might reconcile studies on the self highlighting the DN, with studies on interoception focusing on the insula.
Journal ArticleDOI

Phenomenology and neurobiology of self disorder in schizophrenia: Primary factors

TL;DR: It is argued that comprehension of schizophrenia may require combining a phenomenological perspective emphasizing disorders of basic-self experience ("ipseity disturbance") with a multidimensional appreciation of possible neurobiological correlates--both primary and secondary.
Journal ArticleDOI

Neural mechanisms of attentional reorienting in three-dimensional space.

TL;DR: This fMRI study constructed a virtual 3D environment in the MR scanner and by presenting targets either close to or far from the participants in an adapted version of the Posner spatial-cueing paradigm, investigated the behavioral and neural mechanisms underlying visuospatial orienting/reorienting in depth.
Journal ArticleDOI

Anticipatory brain activity predicts the success or failure of subsequent emotion regulation

TL;DR: Examination of brain activity when anticipating the need to cognitively reappraise aversive images, amygdala responses to those images and subsequent success in diminishing negative affect suggests that anticipation facilitates successful reappraisal via reduced anticipatory prefrontal 'cognitive' elaboration and better integration of affective information in paralimbic and subcortical systems.
Journal ArticleDOI

Similarities and differences in the default mode network across rest, retrieval, and future imagining.

TL;DR: Results suggest that DMN connectivity may be more flexible than previously considered, in line with emerging evidence that the DMN is not a static network engaged commonly across distinct cognitive processes, but is instead a dynamic system, topographically changing in relation to ongoing cognitive demands.
References
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Journal ArticleDOI

A default mode of brain function.

TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
Journal ArticleDOI

AFNI: software for analysis and visualization of functional magnetic resonance neuroimages

TL;DR: A package of computer programs for analysis and visualization of three-dimensional human brain functional magnetic resonance imaging (FMRI) results is described and techniques for automatically generating transformed functional data sets from manually labeled anatomical data sets are described.
Journal ArticleDOI

The Brain's Default Network Anatomy, Function, and Relevance to Disease

TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.
Journal ArticleDOI

The human brain is intrinsically organized into dynamic, anticorrelated functional networks

TL;DR: It is suggested that both task-driven neuronal responses and behavior are reflections of this dynamic, ongoing, functional organization of the brain, featuring the presence of anticorrelated networks in the absence of overt task performance.
Journal ArticleDOI

Functional connectivity in the resting brain: A network analysis of the default mode hypothesis

TL;DR: This study constitutes, to the knowledge, the first resting-state connectivity analysis of the default mode and provides the most compelling evidence to date for the existence of a cohesive default mode network.
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