How the environment affects mental health.
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For many years there was an assumption that the extensive documentation of statistical associations between risky environments and mental disorders necessarily represented the operation of environmentally mediated causal mechanisms.Abstract:
For many years there was an assumption that the extensive documentation of statistical associations between risky environments and mental disorders necessarily represented the operation of environmentally mediated causal mechanisms. Three considerations challenged that assumption. First,read more
Citations
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Gene-Environment Interactions in Schizophrenia: Review of Epidemiological Findings and Future Directions
TL;DR: Experimental ecogenetic approaches with randomized assignment may help to overcome some of the limitations of observational studies and allow for the additional elucidation of underlying mechanisms using a combination of functional enviromics and functional genomics.
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Neurobiological and psychiatric consequences of child abuse and neglect
TL;DR: Most patients who have experienced early traumatic experiences are likely best treated with a combination of psychotherapy and pharmacotherapy, and the few current treatment outcome studies relevant to this research area are described.
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Does the Concept of “Sensitization” Provide a Plausible Mechanism for the Putative Link Between the Environment and Schizophrenia?
TL;DR: The behavioral phenotype for sensitization may be examined by quantifying, in populations exposed to environmental risk factors associated with stress or dopamine-agonist drugs, the increased rate of persistence (indicating lasting sensitization) of normally transient developmental expressions of subclinical psychotic experiences and the subsequent increase rate of transition to clinical psychotic disorder.
Journal ArticleDOI
Family relationships in childhood and common psychiatric disorders in later life: systematic review of prospective studies
TL;DR: Given the prevalence and disabling nature of common psychiatric problems, these studies highlight the need to minimise harm associated with dysfunctional parent–child relationships.
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Mental health in Dutch adolescents : A TRAILS report on prevalence, severity, age of onset, continuity and co-morbidity of DSM disorders
Johan Ormel,Dennis Raven,F. V. A. van Oort,Catharina A. Hartman,Sijmen A. Reijneveld,René Veenstra,Wilma A. M. Vollebergh,Jan K. Buitelaar,Frank C. Verhulst,Albertine J. Oldehinkel +9 more
TL;DR: This psychopathology is rather persistent, mostly due to recurrence, showing both monotypic and heterotypic continuity, with family context affecting particularly externalizing disorders.
References
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Epigenetic programming by maternal behavior.
Ian C. G. Weaver,Nadia Cervoni,Frances A. Champagne,Ana C. D'Alessio,Shakti Sharma,Jonathan R. Seckl,Sergiy Dymov,Moshe Szyf,Michael J. Meaney +8 more
TL;DR: It is shown that an epigenomic state of a gene can be established through behavioral programming, and it is potentially reversible, suggesting a causal relation among epigenomicState, GR expression and the maternal effect on stress responses in the offspring.
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A reinterpretation of the direction of effects in studies of socialization.
TL;DR: In this article, a set of propositions concerning the effects of congenital factors in children on parent behavior are presented, which can be interpreted plausibly as indicating effects of children on parents.
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Why are children in the same family so different from one another
Robert Plomin,Denise Daniels +1 more
TL;DR: For example, the authors found that environmental differences between children in the same family represent the major source of environmental variance for personality, psychopathology, and cognitive abilities, and found that these environmental influences make two children in a same family as different from one another as are pairs of children selected randomly from the population.
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Trajectories of change in criminal offending: Good marriages and the desistance process.
TL;DR: In this article, the authors draw an analogy between changes in criminal offending spurred by the formation of social bonds and an investment process, and show that desistance from crime is facilitated by the development of quality marital bonds and that this influence is gradual and cumulative over time.
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Time trends in adolescent mental health.
TL;DR: Analysis of longitudinal data from the first two cohorts showed that long-term outcomes for adolescents with conduct problems were closely similar, providing evidence that observed trends were unaffected by possible changes in reporting thresholds.