Journal ArticleDOI
Hyperglycaemia, stress oxidant, liver dysfunction and histological changes in diabetic male rat pancreas and liver: Protective effect of 17β-estradiol
Khaled Hamden,Serge Carreau,Mohamed Ali Boujbiha,Samiha Lajmi,Dorra Aloulou,Dalanda Kchaou,Abdelfattah Elfeki +6 more
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TLDR
It was shown that 17 beta-estradiol could attenuate the increase of blood glucose in plasma and normalise the hepatic glycogen level, and protects against alloxan-induced pancreatic beta-cells and hepatic cells damages.About:
This article is published in Steroids.The article was published on 2008-05-01. It has received 69 citations till now. The article focuses on the topics: Glutathione peroxidase & Diabetes mellitus.read more
Citations
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Journal ArticleDOI
Mechanisms of Diabetes-Induced Liver Damage: The role of oxidative stress and inflammation
TL;DR: This review summarises the biochemical, histological and macromolecular changes that contribute to oxidative liver damage among diabetic individuals.
Journal ArticleDOI
Hypoglycemic and antioxidant effects of phenolic extracts and purified hydroxytyrosol from olive mill waste in vitro and in rats.
TL;DR: This study demonstrates for the first time that OMW polyphenols and especially (HT) are efficient in inhibiting hyperglycemia and oxidative stress induced by diabetes and suggests that administration of HT may be helpful in the prevention of diabetic complications associated with oxidative stress.
Journal ArticleDOI
Hypoglycemic and antilipidemic properties of kombucha tea in alloxan-induced diabetic rats.
Ahmed Aloulou,Khaled Hamden,Dhouha Elloumi,Madiha Bou Ali,Khaoula Hargafi,Bassem Jaouadi,Fatma Ayadi,Abdelfattah Elfeki,Emna Ammar +8 more
TL;DR: Kombucha tea can be considered as a potential strong candidate for future application as a functional supplement for the treatment and prevention of diabetes and a better suppressor of increased blood glucose levels.
Journal ArticleDOI
Hypoglycemic and antioxidant effects of leaf essential oil of Pelargonium graveolens L’Hér. in alloxan induced diabetic rats
TL;DR: The results suggest that the rose-scented geranium could be used as a safe alternative antihyperglycemic drug for diabetic patients and administration of essential oil of P. graveolens may be helpful in the prevention of diabetic complications associated with oxidative stress.
Journal ArticleDOI
1α, 25 Dihydroxyvitamin D3 : Therapeutic and Preventive Effects against Oxidative Stress, Hepatic, Pancreatic and Renal Injury in Alloxan-Induced Diabetes in Rats
Khaled Hamden,Serge Carreau,Kamel Jamoussi,Slaheddine Miladi,Samiha Lajmi,Dorra Aloulou,Fatma Ayadi,Abdelfattah Elfeki +7 more
TL;DR: It is concluded that 1α,25(OH)2VD3 might be useful for the therapy and prevention of diabetes and the numerous side effects especially toxicity in liver, pancreas and kidneys and this protective effect is more obvious in the preventive experiment.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Book ChapterDOI
Catalase in vitro
TL;DR: In this article, the catalytic activity of catalase has been investigated using ultraviolet (UV) spectrophotometry and Titrimetric methods, which is suitable for comparative studies for large series of measurements.
Book ChapterDOI
Microsomal lipid peroxidation.
John A. Buege,Steven D. Aust +1 more
TL;DR: This chapter discusses microsomal lipid peroxidation, a complex process known to occur in both plants and animals that involves the formation and propagation of lipid radicals, the uptake of oxygen, a rearrangement of the double bonds in unsaturated lipids, and the eventual destruction of membrane lipids.
Journal ArticleDOI
Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
TL;DR: Glutathione peroxidase activity is found to be associated with a relatively stable, nondialyzable, heat-labile, intracellular component which is separable from hemoglobin, by gel filtration and ammonium sulfate precipitation.
Journal ArticleDOI
Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase
TL;DR: The autoxidation of pyrogallol was investigated in the presence of EDTA in the pH range 7.9–10.6, indicating an almost total dependence on the participation of the superoxide anion radical, O2·−, in the reaction.