Journal ArticleDOI
Identification of Rhus verniciflua Stokes compounds that exhibit free radical scavenging and anti-apoptotic properties.
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The results suggest that the flavonoid derivatives in F(2) are the compounds in the RVS ethanol extract that act as antioxidants.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 2002-04-15. It has received 170 citations till now. The article focuses on the topics: Fustin.read more
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Antioxidant property of an ethanol extract of the stem of Opuntia ficus-indica var. saboten.
TL;DR: The OFS ethanol extract was found to be effective in protecting plasmid DNA against the strand breakage induced by hydroxyl radicals in a Fenton's reaction mixture and showed significant dose-dependent protection of mouse splenocytes against glucose oxidase-mediated cytotoxicity.
Journal ArticleDOI
Naturally occurring chalcones and their biological activities
Zsuzsanna Rozmer,Pál Perjési +1 more
TL;DR: The aim of this review is to summarize the various naturally occurring chalcone compounds which have been isolated from different plants to initiate further pharmacobotanical, biotechnological and medicinal studies on the field of chal cone research.
Journal ArticleDOI
Biological activities of extracts from sumac (Rhus spp.): a review
Sierra Rayne,G. Mazza +1 more
TL;DR: There remains a significant research gap spanning the range from lead chemical discovery through process development and optimization in order to better understand the full potential of the Rhus genus as part of global green technology based on bioproducts and bioprocesses research programs.
Journal ArticleDOI
Butein, a Tetrahydroxychalcone, Inhibits Nuclear Factor (NF)-κB and NF-κB-regulated Gene Expression through Direct Inhibition of IκBα Kinase β on Cysteine 179 Residue *
Manoj K. Pandey,Santosh K. Sandur,Bokyung Sung,Gautam Sethi,Ajaikumar B. Kunnumakkara,Bharat B. Aggarwal +5 more
TL;DR: The results indicated that antitumor and anti-inflammatory activities previously assigned to butein may be mediated in part through the direct inhibition of IKK, leading to the suppression of the NF-κB activation pathway.
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Flavonol-rich RVHxR from Rhus verniciflua Stokes and its major compound fisetin inhibits inflammation-related cytokines and angiogenic factor in rheumatoid arthritic fibroblast-like synovial cells and in vivo models.
TL;DR: It is suggested that flavonol-rich RVHxR and its major compound fisetin have shown potent suppressive effects on some inflammatory cytokines/chemokines and angiogenic factor in IL-1beta-stimulated RA FLS and inflammatory in vivo models.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
TL;DR: A tetrazolium salt has been used to develop a quantitative colorimetric assay for mammalian cell survival and proliferation and is used to measure proliferative lymphokines, mitogen stimulations and complement-mediated lysis.
Book ChapterDOI
Role of free radicals and catalytic metal ions in human disease: an overview.
TL;DR: The chapter discusses the metabolism of transition metals, such as iron and copper, and the chelation therapy that is an approach to site-specific antioxidant protection.
Journal ArticleDOI
Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer.
Helen Wiseman,Barry Halliwell +1 more
TL;DR: ROS and RNS could contribute to the initiation of cancer, in addition to being important in the promotion and progression phases, as evidence is growing that antioxidants may prevent or delay the onset of some types of cancer.
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The deoxyribose method: a simple "test-tube" assay for determination of rate constants for reactions of hydroxyl radicals.
TL;DR: It is suggested that the deoxyribose assay is a simple and cheap alternative to pulse radiolysis for determination of rate constants for reaction of most biological molecules with hydroxyl radicals.