Journal ArticleDOI
IgG4-related disease
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TLDR
Identification of specific antigens and T-cell clones that drive the disease will be the first steps to elucidate the pathogenesis of IgG4-related disease.Citations
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Pseudotumor orbitario relacionado con IgG4
Rebeca Fernández Regueiro,Eva María Fonseca Aizpuru,Carolina Estrada Menéndez,Loreto Buznego Suárez +3 more
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Les sous-classes d’IgG dans le LCR présentent-elles un réel intérêt ?
TL;DR: In this article , the authors present the indications of total IgG and IgG subclasses on serum as well as the benefit of IgG subsclasses in CSF and the techniques available in a medical laboratory.
Journal ArticleDOI
Unexplained liver dysfunction in a young Chinese man with eosinophilia.
TL;DR: A 37-year-old man complained of a 7 months’ history of yellowish skin and sclera accompanied by fatigue, pruritus and dry mouth, with a history of subcutaneous masses on his elbow.
Journal ArticleDOI
IgG4 Related Disease Presenting as Simultaneous Pancreatic and Lung Mass Mimicking Malignancy
Xiaoqi Wang,Peilin Zhang,Kran Suknuntha,Kwok-Kei Lee,Eugene Shostak,Vijay Jaswani,Jen-Chin Wang +6 more
TL;DR: In this article , a 70 years old Asian male, presented both simultaneously as a pancreatic mass with obstructive jaundice and a lung mass, the patient underwent whipple procedure and was found that the mass lesion of the pancreas is not malignancy but IgG4-RD.
Journal ArticleDOI
IgG4-related disease presenting as a paraneoplastic syndrome: report of two cases and literature review.
Mitsuteru Akahoshi,Yojiro Arinobu,Yusuke Kashiwado,Aya Omoto,Masahiro Ayano,Hiroki Mitoma,Yasutaka Kimoto,Nobuyuki Ono,Takahiko Horiuchi,Hiroaki Niiro +9 more
TL;DR: This work reports two cases of IgG4-RD with suspected paraneoplastic syndrome, and in both patients, malignancy was observed immediately after diagnosis, and surgical resection resulted in spontaneous regression of IgT3-RD.
References
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TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties.
Tim R. Mosmann,R L Coffman +1 more
TL;DR: Two types of cloned helper T cells are described, defined primarily by differences in the pattern of lymphokines ynthesized, and the different functions of the two types of cells and their lymphokine synthesis are discussed.
Journal ArticleDOI
Differentiation of Effector CD4 T Cell Populations
TL;DR: This review summarizes the discovery, functions, and relationships among Th cells; the cytokine and signaling requirements for their development; the networks of transcription factors involved in their differentiation; the epigenetic regulation of their key cytokines and transcription factors; and human diseases involving defective CD4 T cell differentiation.
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Alternative Activation of Macrophages: An Immunologic Functional Perspective
TL;DR: The cellular sources of these cytokines, receptor signaling pathways, and induced markers and gene signatures are reviewed and the concept of macrophage activation in the context of the immune response is revisit.
Journal ArticleDOI
The regulation of IL-10 production by immune cells
Margarida Saraiva,Anne O'Garra +1 more
TL;DR: Understanding the specific molecular events that regulate the production of IL-10 will help to answer the remaining questions that are important for the design of new strategies of immune intervention.
Journal ArticleDOI
High serum IgG4 concentrations in patients with sclerosing pancreatitis.
Hideaki Hamano,Shigeyuki Kawa,Akira Horiuchi,Hiroshi Unno,Naoyuki Furuya,Taiji Akamatsu,Mana Fukushima,Toshio Nikaido,Kohzo Nakayama,Nobuteru Usuda,Kendo Kiyosawa +10 more
TL;DR: Patients with sclerosing pancreatitis have high serum IgG4 concentrations, providing a useful means of distinguishing this disorder from other diseases of the pancreas or biliary tract.
Related Papers (5)
Consensus statement on the pathology of IgG4-related disease
Vikram Deshpande,Yoh Zen,John Kc Chan,Eunhee E Yi,Yasuharu Sato,Tadashi Yoshino,Günter Klöppel,J. Godfrey Heathcote,Arezou Khosroshahi,Judith A. Ferry,Rob C. Aalberse,Daniel Bloch,William R. Brugge,Adrian C Bateman,Mollie N. Carruthers,Suresh T. Chari,Wah Cheuk,Lynn D. Cornell,Carlos Fernandez-del Castillo,David G. Forcione,Daniel L. Hamilos,Terumi Kamisawa,Satomi Kasashima,Shigeyuki Kawa,Mitsuhiro Kawano,Gregory Y. Lauwers,Yasufumi Masaki,Yasuni Nakanuma,Kenji Notohara,Kazuichi Okazaki,Ji Kon Ryu,Takako Saeki,Dushyant V. Sahani,Thomas C. Smyrk,James Robert Stone,Masayuki Takahira,George Webster,Motohisa Yamamoto,Giuseppe Zamboni,Hisanori Umehara,John H. Stone +40 more
Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011
Hisanori Umehara,Kazuichi Okazaki,Yasufumi Masaki,Mitsuhiro Kawano,Motohisa Yamamoto,Takako Saeki,Shoko Matsui,Tadashi Yoshino,Shigeo Nakamura,Shigeyuki Kawa,Hideaki Hamano,Terumi Kamisawa,Toru Shimosegawa,Akira Shimatsu,Seiji Nakamura,Tetsuhide Ito,Kenji Notohara,Takayuki Sumida,Yoshiya Tanaka,Tsuneyo Mimori,Tsutomu Chiba,Michiaki Mishima,Toshifumi Hibi,Hirohito Tsubouchi,Kazuo Inui,Hirotaka Ohara +25 more
International Consensus Guidance Statement on the Management and Treatment of IgG4-Related Disease
Arezou Khosroshahi,Zachary S. Wallace,J. L. Crowe,Takashi Akamizu,Atsushi Azumi,M. N. Carruthers,Suresh T. Chari,Emanuel Della-Torre,Luca Frulloni,Hiroshi Goto,Phil A. Hart,Terumi Kamisawa,Shigeyuki Kawa,Mitsuhiro Kawano,Myung-Hwan Kim,Yuzo Kodama,Kensuke Kubota,Markus M. Lerch,Matthias Löhr,Yasufumi Masaki,Shoko Matsui,Tsuneyo Mimori,Seiji Nakamura,Takahiro Nakazawa,Hirotaka Ohara,Kazuichi Okazaki,Jay H. Ryu,Takako Saeki,Nicolas Schleinitz,Akira Shimatsu,Toru Shimosegawa,Hiroki Takahashi,Masayuki Takahira,Atsushi Tanaka,Mark Topazian,Hisanori Umehara,George J. Webster,Thomas E. Witzig,Motohisa Yamamoto,W. Zhang,Tsutomu Chiba,John H. Stone +41 more