Journal ArticleDOI
IgG4-related disease
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TLDR
Identification of specific antigens and T-cell clones that drive the disease will be the first steps to elucidate the pathogenesis of IgG4-related disease.Citations
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IgG4-Related Disease: Clinical and Laboratory Features in One Hundred Twenty-Five Patients.
Zachary S. Wallace,Vikram Deshpande,Hamid Mattoo,Vinay Mahajan,Maria Kulikova,Shiv Pillai,John H. Stone +6 more
TL;DR: In this article, the authors report detailed clinical and laboratory findings in a larger group of patients with IgG4-related disease whose diagnosis was established by strict clinicopathologic correlation.
Journal ArticleDOI
The 2019 American College of Rheumatology/European League Against Rheumatism classification criteria for IgG4-related disease
Zachary S. Wallace,Ray Naden,Suresh T. Chari,Hyon K. Choi,Emanuel Della-Torre,Jean Francois Dicaire,Phillip A. Hart,Dai Inoue,Mitsuhiro Kawano,Arezou Khosroshahi,Marco Lanzillotta,Kazuichi Okazaki,Cory A. Perugino,Amita Sharma,Takako Saeki,Nicolas Schleinitz,Naoki Takahashi,Hisanori Umehara,Yoh Zen,John H. Stone +19 more
TL;DR: In this article, an international multispecialty group of 86 physicians was assembled by the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR).
Journal ArticleDOI
IgG4-Related Disease: Dataset of 235 Consecutive Patients
Dai Inoue,Kotaro Yoshida,Norihide Yoneda,Kumi Ozaki,Takashi Matsubara,Keiichi Nagai,Kenichirou Okumura,Fumihito Toshima,Jun Toyama,Tetsuya Minami,Osamu Matsui,Toshifumi Gabata,Yoh Zen +12 more
TL;DR: A reliable dataset could improve the characterization of IgG4-RD, particularly its unique demography and the frequency of each organ manifestation, using a large cohort of patients.
Journal ArticleDOI
The 2019 American College of Rheumatology/European League Against Rheumatism Classification Criteria for IgG4-Related Disease.
Zachary S. Wallace,Ray Naden,Suresh T. Chari,Hyon K. Choi,Emanuel Della-Torre,Jean Francois Dicaire,Phil A. Hart,Dai Inoue,Mitsuhiro Kawano,Arezou Khosroshahi,Kensuke Kubota,Marco Lanzillotta,Kazuichi Okazaki,Cory A. Perugino,Amita Sharma,Takako Saeki,Hiroshi Sekiguchi,Nicolas Schleinitz,James R. Stone,Naoki Takahashi,Hisanori Umehara,George Webster,Yoh Zen,John H. Stone +23 more
TL;DR: This work was undertaken to develop and validate an international set of classification criteria for IgG4‐RD, which can cause fibroinflammatory lesions in nearly any organ.
Journal ArticleDOI
Clonal expansion of CD4+ cytotoxic T lymphocytes in patients with IgG4-related disease
Hamid Mattoo,Vinay Mahajan,Takashi Maehara,Vikram Deshpande,Emanuel Della-Torre,Zachary S. Wallace,Maria Kulikova,Jefte M. Drijvers,Joe Daccache,Mollie N. Carruthers,Flavia V. Castelino,James R. Stone,John H. Stone,Shiv Pillai +13 more
TL;DR: IgG4-RD is prominently linked to clonally expanded IL-1β- and TGF-β1-secreting CD4(+) CTLs in both peripheral blood and inflammatory tissue lesions.
References
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Journal ArticleDOI
Standard steroid treatment for autoimmune pancreatitis
Terumi Kamisawa,Tooru Shimosegawa,Kazuichi Okazaki,Takayoshi Nishino,Hiroyuki Watanabe,Atsushi Kanno,Fumihiro Okumura,Tomoya Nishikawa,Kenso Kobayashi,Tamaki Ichiya,Hajime Takatori,Keisuke Yamakita,Kensuke Kubota,Hideaki Hamano,Keiya Okamura,Kenji Hirano,Tetsuhide Ito,Sbh Ko,Masao Omata +18 more
TL;DR: The major indication for steroid treatment in AIP is the presence of symptoms, and an initial prednisolone dose of 0.6 mg/kg/day, is recommend, which is then reduced to a maintenance dose over a period of 3–6 months.
Journal ArticleDOI
Follicular B helper T cells in antibody responses and autoimmunity.
TL;DR: Owing to their distinct homing preferences and helper function, these T cells differ from T helper 1 and T helper 2 cells and have been denoted follicular B helper T cells.
Journal ArticleDOI
Recommendations for the nomenclature of IgG4-related disease and its individual organ system manifestations
John H. Stone,Arezou Khosroshahi,Vikram Deshpande,John K.C. Chan,J. Godfrey Heathcote,Rob C. Aalberse,Atsushi Azumi,Daniel Bloch,William R. Brugge,Mollie N. Carruthers,Wah Cheuk,Lynn D. Cornell,Carlos Fernandez-del Castillo,Judith A. Ferry,David G. Forcione,Günter Klöppel,Daniel L. Hamilos,Terumi Kamisawa,Satomi Kasashima,Shigeyuki Kawa,Mitsuhiro Kawano,Yasufumi Masaki,Kenji Notohara,Kazuichi Okazaki,Ji Kon Ryu,Takako Saeki,Dushyant V. Sahani,Yasuharu Sato,Thomas C. Smyrk,James R. Stone,Masayuki Takahira,Hisanori Umehara,George Webster,Motohisa Yamamoto,Eunhee S. Yi,Tadashi Yoshino,Giuseppe Zamboni,Yoh Zen,Suresh T. Chari +38 more
TL;DR: John H. Stone, Arezou Khosroshahi, Vikram Deshpande, John K.Stone, Masayuki Takahira, Hisanori Umehara, George Webster, Motohisa Yamamoto, Eunhee Yi, Tadashi Yoshino, Giuseppe Zamboni, Yoh Zen, and Suresh Chari.
Journal ArticleDOI
Th2 and regulatory immune reactions are increased in immunoglobin G4-related sclerosing pancreatitis and cholangitis.
Yoh Zen,Takahiko Fujii,Kenichi Harada,Mitsuhiro Kawano,Kazunori Yamada,Masayuki Takahira,Yasuni Nakanuma +6 more
TL;DR: AIPC is a unique inflammatory disorder characterized by an immune reaction predominantly mediated by Th2 cells and Tregs, which could be characterized by the over‐production of T helper (Th) 2 and regulatory cytokines.
Journal ArticleDOI
Histopathological features of diagnostic and clinical relevance in autoimmune pancreatitis: a study on 53 resection specimens and 9 biopsy specimens
Giuseppe Zamboni,Jutta Lüttges,Paola Capelli,Luca Frulloni,Giorgio Cavallini,Paolo Pederzoli,Alexander Leins,Daniel S. Longnecker,Günter Klöppel +8 more
TL;DR: Periductal lymphoplasmacytic infiltration and fibrosis, preferential occurrence in the pancreatic head and venulitis characterize autoimmune pancreatitis.
Related Papers (5)
Consensus statement on the pathology of IgG4-related disease
Vikram Deshpande,Yoh Zen,John Kc Chan,Eunhee E Yi,Yasuharu Sato,Tadashi Yoshino,Günter Klöppel,J. Godfrey Heathcote,Arezou Khosroshahi,Judith A. Ferry,Rob C. Aalberse,Daniel Bloch,William R. Brugge,Adrian C Bateman,Mollie N. Carruthers,Suresh T. Chari,Wah Cheuk,Lynn D. Cornell,Carlos Fernandez-del Castillo,David G. Forcione,Daniel L. Hamilos,Terumi Kamisawa,Satomi Kasashima,Shigeyuki Kawa,Mitsuhiro Kawano,Gregory Y. Lauwers,Yasufumi Masaki,Yasuni Nakanuma,Kenji Notohara,Kazuichi Okazaki,Ji Kon Ryu,Takako Saeki,Dushyant V. Sahani,Thomas C. Smyrk,James Robert Stone,Masayuki Takahira,George Webster,Motohisa Yamamoto,Giuseppe Zamboni,Hisanori Umehara,John H. Stone +40 more
Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011
Hisanori Umehara,Kazuichi Okazaki,Yasufumi Masaki,Mitsuhiro Kawano,Motohisa Yamamoto,Takako Saeki,Shoko Matsui,Tadashi Yoshino,Shigeo Nakamura,Shigeyuki Kawa,Hideaki Hamano,Terumi Kamisawa,Toru Shimosegawa,Akira Shimatsu,Seiji Nakamura,Tetsuhide Ito,Kenji Notohara,Takayuki Sumida,Yoshiya Tanaka,Tsuneyo Mimori,Tsutomu Chiba,Michiaki Mishima,Toshifumi Hibi,Hirohito Tsubouchi,Kazuo Inui,Hirotaka Ohara +25 more
International Consensus Guidance Statement on the Management and Treatment of IgG4-Related Disease
Arezou Khosroshahi,Zachary S. Wallace,J. L. Crowe,Takashi Akamizu,Atsushi Azumi,M. N. Carruthers,Suresh T. Chari,Emanuel Della-Torre,Luca Frulloni,Hiroshi Goto,Phil A. Hart,Terumi Kamisawa,Shigeyuki Kawa,Mitsuhiro Kawano,Myung-Hwan Kim,Yuzo Kodama,Kensuke Kubota,Markus M. Lerch,Matthias Löhr,Yasufumi Masaki,Shoko Matsui,Tsuneyo Mimori,Seiji Nakamura,Takahiro Nakazawa,Hirotaka Ohara,Kazuichi Okazaki,Jay H. Ryu,Takako Saeki,Nicolas Schleinitz,Akira Shimatsu,Toru Shimosegawa,Hiroki Takahashi,Masayuki Takahira,Atsushi Tanaka,Mark Topazian,Hisanori Umehara,George J. Webster,Thomas E. Witzig,Motohisa Yamamoto,W. Zhang,Tsutomu Chiba,John H. Stone +41 more