Journal ArticleDOI
Immunofluorescent and ultrastructural studies of polygonal microfilament networks in respreading non-muscle cells.
William E. Gordon,Anne Bushnell +1 more
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The results support earlier conclusions that polygonal networks are structural intermediates responsible for organizing contractile proteins of the cortical microfilament layer into stress fibers.About:
This article is published in Experimental Cell Research.The article was published on 1979-05-01. It has received 54 citations till now. The article focuses on the topics: Microfilament & Heavy meromyosin.read more
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The role of TGF-β in the pathogenesis of primary open-angle glaucoma.
Rudolf Fuchshofer,Ernst R. Tamm +1 more
TL;DR: The available data strongly indicate that TGF-β2 is a key player contributing to the structural changes in the extracellular matrix (ECM) of the trabecular meshwork and optic nerve head as characteristically seen in POAG.
Journal ArticleDOI
The relationship between stress fiber-like structures and nascent myofibrils in cultured cardiac myocytes.
TL;DR: A complex, multistage molecular model is presented for myofibrillar assembly and maturation and it is of considerable theoretical interest to note that mature cardiac myocytes, like mature skeletal myotubes, lack readily detectable stress fibers.
Journal ArticleDOI
Building the actin cytoskeleton: filopodia contribute to the construction of contractile bundles in the lamella
TL;DR: Findings in fish fibroblasts support the idea that filaments generated in filopodia and lamellipodia for protrusion are recycled for seeding actomyosin arrays for use in retraction.
Journal ArticleDOI
Differences in the stress fibers between fibroblasts and epithelial cells.
TL;DR: A sarcomeric model of stress fiber structure is proposed based on light and electron microscopic findings that suggest that the densities seen in the electron microscope are sites of alpha-actinin localization and that the proteins in stress fibers have an arrangement similar to that in striated muscle.
Journal ArticleDOI
Ultrastructural localization of alpha-actinin and filamin in cultured cells with the immunogold staining (IGS) method.
TL;DR: By using antiactin immunogold staining as a control, the applicability of the method to the microfilament system is demonstrated and the results confirm and extend the data from light microscopic investigations and provide more information on the structural basis of the micro Filament system.
References
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Journal ArticleDOI
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products.
Journal Article
Cleavage of structural proteins during the assemble of the head of bacterio-phage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products as mentioned in this paper.
Journal ArticleDOI
[Method permitting the combined study of the electrophoretic and the immunochemical properties of protein mixtures; application to blood serum].
P. Grabar,C.A. Williams +1 more
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α-Actinin: Immunofluorescent localization of a muscle structural protein in nonmuscle cells
Elias Lazarides,Keith Burridge +1 more
TL;DR: The results suggest that alpha-actinin may be involved in the organization ofActin filament bundles, in the attachment of actin filaments to the plasma membrane, and in the assembly of actIn filaments in areas of cell to cell contact.
Journal ArticleDOI
Actin, alpha-actinin, and tropomyosin interaction in the structural organization of actin filaments in nonmuscle cells.
TL;DR: These results demonstrate a specific interaction of alpha-actinin and tropomyosin with actin filaments during the assembly and organization of the actin filament bundles of tissue culture cells.
Related Papers (5)
Actin, alpha-actinin, and tropomyosin interaction in the structural organization of actin filaments in nonmuscle cells.
α-Actinin: Immunofluorescent localization of a muscle structural protein in nonmuscle cells
Elias Lazarides,Keith Burridge +1 more