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Proceedings ArticleDOI

Improving MRI-based diagnosis of Alzheimer's disease via an ensemble privileged information learning algorithm

TLDR
The experimental results demonstrate that the proposed RBM+ works well as an LUPI algorithm for feature learning, and the ensemble L UPI algorithm is superior to the traditional predictive models for the MRI-based AD diagnosis using the positron emission tomography as the privileged information.
Abstract
In clinical practice, the magnetic resonance imaging (MRI) is a prevalent neuroimaging technique for Alzheimer's disease (AD) diagnosis. As a learning using privileged information (LUPI) algorithm, SVM+ has shown its effectiveness on the classification of brain disorders, with single-modal neuroimaging samples for testing but multimodal neuroimaging samples for training. In this work, we propose to apply the multimodal restricted Boltzmann machines (RBM) as an LUPI algorithm for feature learning so as to form an RBM+ algorithm. Furthermore, an ensemble LUPI algorithm is developed, integrating SVM+ and RBM+ by the multiple kernel boosting based strategy. The experimental results demonstrate that the proposed RBM+ works well as an LUPI algorithm for feature learning, and the ensemble LUPI algorithm is superior to the traditional predictive models for the MRI-based AD diagnosis using the positron emission tomography as the privileged information.

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Citations
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Journal ArticleDOI

Automatic assessment of Alzheimer’s disease diagnosis based on deep learning techniques

TL;DR: This study proved that DL models could be built in these fields, whereas TL is an essential tool for completing the task with fewer examples, and sagittal-plane MRIs were, at least, as effective as MRI from other planes at identifying AD in early stages.
Journal ArticleDOI

Cascaded Multi-Column RVFL+ Classifier for Single-Modal Neuroimaging-Based Diagnosis of Parkinson's Disease

TL;DR: The experimental results on both the transcranial sonography data set and the magnetic resonance imaging data set for PD show that the proposed cmcRVFL+ algorithm achieves superior performance to all the compared algorithms, and suggest that it has the potential to be flexibly applied to various single-modal imaging based CAD.
Journal ArticleDOI

Deep Convolutional Neural Networks With Ensemble Learning and Generative Adversarial Networks for Alzheimer's Disease Image Data Classification.

TL;DR: In this article, the authors explore potential interdisciplinary approaches for early detection and provide insight into recent advances on AD classification using 3D CNN architectures for multi-modal PET/MRI data.
References
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Journal ArticleDOI

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TL;DR: This review covers computer-assisted analysis of images in the field of medical imaging and introduces the fundamentals of deep learning methods and their successes in image registration, detection of anatomical and cellular structures, tissue segmentation, computer-aided disease diagnosis and prognosis, and so on.
Journal ArticleDOI

Multimodal Classification of Alzheimer’s Disease and Mild Cognitive Impairment

TL;DR: Three modalities of biomarkers are proposed to combine, i.e., MRI, FDG-PET, and CSF biomarkers, to discriminate between AD (or MCI) and healthy controls, using a kernel combination method, and shows considerably better performance, compared to the case of using an individual modality of biomarker.
Journal ArticleDOI

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TL;DR: A novel method for a high-level latent and shared feature representation from neuroimaging modalities via deep learning that could hierarchically discover the complex latent patterns inherent in both MRI and PET.
Proceedings Article

A new learning paradigm: Learning using privileged information

TL;DR: Details of the new paradigm and corresponding algorithms are discussed, some new algorithms are introduced, several specific forms of privileged information are considered, and superiority of thenew learning paradigm over the classical learning paradigm when solving practical problems is demonstrated.
Journal ArticleDOI

Learning With Augmented Features for Supervised and Semi-Supervised Heterogeneous Domain Adaptation

TL;DR: This paper proposes a novel method called Heterogeneous Feature Augmentation (HFA) based on SVM which can simultaneously learn the target classifier as well as infer the labels of unlabeled target samples and shows that the SHFA and HFA outperform the existing HDA methods.
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