In vivo degradation of three-dimensional silk fibroin scaffolds.
Yongzhong Wang,Darya Rudym,Ashley Walsh,Lauren Abrahamsen,Hyeon-Joo Kim,Hyun-Suk Kim,Carl A. Kirker-Head,David L. Kaplan +7 more
TLDR
The results demonstrate that the in vivo behavior of the three-dimensional silk fibroin scaffolds is related to the morphological and structural features that resulted from different scaffold preparation processes.About:
This article is published in Biomaterials.The article was published on 2008-08-01 and is currently open access. It has received 709 citations till now. The article focuses on the topics: Fibroin.read more
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Materials fabrication from Bombyx mori silk fibroin
Danielle N. Rockwood,Rucsanda C. Preda,Tuna Yucel,Xiaoqin Wang,Michael L. Lovett,David L. Kaplan +5 more
TL;DR: This protocol includes methods to extract silk from B. mori cocoons to fabricate hydrogels, tubes, sponges, composites, fibers, microspheres and thin films, used directly as biomaterials for implants, as scaffolding in tissue engineering and in vitro disease models, as well as for drug delivery.
Journal ArticleDOI
Biopolymer-based hydrogels as scaffolds for tissue engineering applications: a review
TL;DR: The most relevant biopolymer-based hydrogel systems, the different methods of preparation, as well as an in depth overview of the applications in the field of tissue engineering will be given.
Journal ArticleDOI
Elastomeric biomaterials for tissue engineering
TL;DR: This article provides a comprehensive review on the elastomeric biomaterials used in tissue engineering, with emphasis on the most important candidates to date.
Journal ArticleDOI
A Physically Transient Form of Silicon Electronics
Suk Won Hwang,Hu Tao,Dae-Hyeong Kim,Huanyu Cheng,Jun-Kyul Song,Elliott Rill,Mark A. Brenckle,Bruce Panilaitis,Sang Min Won,Yun-Soung Kim,Young Min Song,Ki Jun Yu,Abid Ameen,Rui Li,Rui Li,Yewang Su,Miaomiao Yang,David L. Kaplan,Mitchell R. Zakin,Marvin J. Slepian,Yonggang Huang,Fiorenzo G. Omenetto,John A. Rogers +22 more
TL;DR: A set of materials, manufacturing schemes, device components, and theoretical design tools for a silicon-based complementary metal oxide semiconductor (CMOS) technology that has this type of transient behavior are reported, together with integrated sensors, actuators, power supply systems, and wireless control strategies.
Journal ArticleDOI
Silk fibroin biomaterials for tissue regenerations.
TL;DR: The present article discusses the processing of silk fibroin into different forms of biomaterials followed by their uses in regeneration of different tissues.
References
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Silk-based biomaterials
Gregory H. Altman,Frank Diaz,Caroline M. Jakuba,Tara Calabro,Rebecca L. Horan,Jingsong Chen,Helen H. Lu,John C. Richmond,David L. Kaplan +8 more
TL;DR: Studies with well-defined silkworm silk fibers and films suggest that the core silk fibroin fibers exhibit comparable biocompatibility in vitro and in vivo with other commonly used biomaterials such as polylactic acid and collagen.
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Liquid crystalline spinning of spider silk.
Fritz Vollrath,David P. Knight +1 more
TL;DR: Successful copying of the spider's internal processing and precise control over protein folding, combined with knowledge of the gene sequences of its spinning dopes, could permit industrial production of silk-based fibres with unique properties under benign conditions.
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Three-dimensional aqueous-derived biomaterial scaffolds from silk fibroin.
TL;DR: These new silk-based three-dimensional matrices provide useful properties as biomaterial matrices due to the all-aqueous mode of preparation, control of pore size, connectivity of pores, degradability and useful mechanical features.
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Porous 3-D scaffolds from regenerated silk fibroin.
TL;DR: Three fabrication techniques were used to form porous three-dimensional silk biomaterial matrixes and the results suggest that silk-based 3D matrixes can be formed for utility in biomaterial applications.
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Stem cell-based tissue engineering with silk biomaterials.
TL;DR: Stem cell-based tissue engineering using 3D silk fibroin scaffolds has expanded the use of silk-based biomaterials as promising scaffolds for engineering a range of skeletal tissues like bone, ligament, and cartilage, as well as connective tissues like skin.