Incidence of co-infections and superinfections in hospitalized patients with COVID-19: a retrospective cohort study.
Carolina Garcia-Vidal,Gemma Sanjuan,Estela Moreno-García,Pedro Puerta-Alcalde,Nicole Garcia-Pouton,Mariana Chumbita,Mariana J. Fernandez-Pittol,Cristina Pitart,Alexy Inciarte,Marta Bodro,Laura Morata,Juan Ambrosioni,Ignacio Grafia,Fernanda Meira,Irene Macaya,Celia Cardozo,Climent Casals,Adrián Téllez,Pedro Castro,Francesc Marco,Felipe García,Josep Mensa,José Antonio Martínez,Alex Soriano,Verónica Rico,Marta Hernández-Meneses,Daiana Agüero,Berta Torres,Ana González,Lorena de la Mora,Jhon Rojas,Laura Linares,Berta Fidalgo,Natalia Rodríguez,David Nicolás,Laia Albiach,Jose Muñoz,Alex Almuedo,Daniel Camprubí,M. A. Marcos,Catia Cilloniz,Sara Fernández,Jose María Nicolás,Antoni Torres +43 more
Reads0
Chats0
TLDR
The burden, epidemiology and outcomes of co-infections and superinfections occurring in hospitalized patients with coronavirus disease 2019 (COVID-19) could prove essential in defining the role of empiric antimicrobial therapy or stewardship strategies.About:
This article is published in Clinical Microbiology and Infection.The article was published on 2021-01-01 and is currently open access. It has received 579 citations till now. The article focuses on the topics: Retrospective cohort study & Cohort study.read more
Citations
More filters
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Prolonged viral shedding provides the rationale for a strategy of isolation of infected patients and optimal antiviral interventions in the future.
Journal ArticleDOI
Prevalence and outcomes of co-infection and superinfection with SARS-CoV-2 and other pathogens: A systematic review and meta-analysis.
Jackson S. Musuuza,Lauren Watson,Vishala Parmasad,Nathan Putman-Buehler,Leslie Christensen,Nasia Safdar +5 more
TL;DR: In this paper, the authors examined the occurrence of co-infections and superinfection and their outcomes among patients with SARS-CoV-2 infection and found that the presence of either coinfection or super-infection was associated with poor outcomes, including increased mortality.
Journal ArticleDOI
Hospital-Acquired Infections in Critically Ill Patients With COVID-19.
Giacomo Grasselli,Giacomo Grasselli,Vittorio Scaravilli,Davide Mangioni,Davide Mangioni,Luigia Scudeller,Laura Alagna,Michele Bartoletti,Giacomo Bellani,Emanuela Biagioni,Paolo Bonfanti,N Bottino,Irene Coloretti,SL Cutuli,SL Cutuli,Gennaro De Pascale,Gennaro De Pascale,Daniela Ferlicca,Gabriele Fior,Andrea Forastieri,Marco Franzetti,Massimiliano Greco,Amedeo Guzzardella,Sara Linguadoca,Marianna Meschiari,Antonio Messina,Gianpaola Monti,Paola Morelli,Antonio Muscatello,Simone Redaelli,Flavia Stefanini,Tommaso Tonetti,Massimo Antonelli,Massimo Antonelli,Maurizio Cecconi,Giuseppe Foti,Roberto Fumagalli,Massimo Girardis,Marco Ranieri,Pierluigi Viale,Mario Carlo Raviglione,Antonio Pesenti,Antonio Pesenti,Andrea Gori,Andrea Gori,Alessandra Bandera +45 more
TL;DR: In this article, a multicenter retrospective analysis of prospectively collected data including adult patients with severe COVID-19 admitted to eight Italian hub hospitals from February 20, 2020, through May 20, 2019 was performed.
Journal ArticleDOI
Ventilator-associated pneumonia in critically ill patients with COVID-19.
Mailis Maes,Ellen Higginson,Joana Pereira-Dias,Martin D. Curran,Surendra Parmar,Fahad A Khokhar,Delphine Cuchet-Lourenço,Janine Lux,Sapna Sharma-Hajela,Benjamin Ravenhill,Islam Hamed,Laura Heales,Razeen Mahroof,Amelia Solderholm,Sally Forrest,Sushmita Sridhar,Sushmita Sridhar,Nicholas M. Brown,Stephen Baker,Vilas Navapurkar,Gordon Dougan,Josefin Bartholdson Scott,Andrew Conway Morris,Andrew Conway Morris +23 more
TL;DR: In this article, the authors compared the incidence of VAP and secondary infections using a combination of microbial culture and a TaqMan multi-pathogen array, and determined the lung microbiome composition using 16S RNA analysis in a subset of samples.
Journal ArticleDOI
COVID-19-Associated Candidiasis (CAC): An Underestimated Complication in the Absence of Immunological Predispositions?
Amir Arastehfar,Agostinho Carvalho,M. Hong Nguyen,Mohammad Taghi Hedayati,Mihai G. Netea,Mihai G. Netea,David S. Perlin,Martin Hoenigl,Martin Hoenigl +8 more
TL;DR: Despite the marked immune dysregulation in COVID-19, no prominent defects have been reported in immune cells that are critically required for immunity to Candida, which suggests that relevant clinical factors, including prolonged ICU stays, central venous catheters, and broad-spectrum antibiotic use, may be key factors causing COVIDs patients to develop IYIs.
References
More filters
Journal ArticleDOI
Clinical Characteristics of Coronavirus Disease 2019 in China.
Wei-jie Guan,Zhengyi Ni,Yu Hu,Wenhua Liang,Chun-Quan Ou,Jianxing He,Lei Liu,Hong Shan,Chunliang Lei,David S.C. Hui,Bin Du,Lanjuan Li,Guang Zeng,Kowk-Yung Yuen,Ruchong Chen,Chun-Li Tang,Tao Wang,Ping-Yan Chen,Jie Xiang,Shiyue Li,Jinlin Wang,Zi-jing Liang,Yi-xiang Peng,Li Wei,Yong Liu,Ya-hua Hu,Peng Peng,Jian-ming Wang,Ji-yang Liu,Zhong Chen,Gang Li,Zhi-jian Zheng,Shao-qin Qiu,Jie Luo,Chang-jiang Ye,Shao-yong Zhu,Nanshan Zhong +36 more
TL;DR: During the first 2 months of the current outbreak, Covid-19 spread rapidly throughout China and caused varying degrees of illness, and patients often presented without fever, and many did not have abnormal radiologic findings.
Journal ArticleDOI
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
Journal ArticleDOI
Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention
Zunyou Wu,Jennifer M. McGoogan +1 more
TL;DR: Hospitalised COVID-19 patients are frequently elderly subjects with co-morbidities receiving polypharmacy, all of which are known risk factors for d
Journal ArticleDOI
Bacterial and Fungal Coinfection in Individuals With Coronavirus: A Rapid Review To Support COVID-19 Antimicrobial Prescribing.
Timothy M. Rawson,Timothy M. Rawson,Luke S. P. Moore,Luke S. P. Moore,Nina Zhu,Nishanthy Ranganathan,Nishanthy Ranganathan,Keira H. Skolimowska,Keira H. Skolimowska,Mark Gilchrist,Mark Gilchrist,Giovanni Satta,Giovanni Satta,Graham S Cooke,Graham S Cooke,Alison Holmes +15 more
TL;DR: Despite frequent prescription of broad-spectrum empirical antimicrobials in patients with coronavirus associated respiratory infections, there is a paucity of data to support the association with respiratory bacterial/fungal co-infection.
Journal ArticleDOI
Rates of Co-infection Between SARS-CoV-2 and Other Respiratory Pathogens.
TL;DR: The prevalence of SARS-CoV-2 co-infection with noncoronavirus respiratory pathogens in a sample of symptomatic patients undergoing PCR testing in March 2020 is described.
Related Papers (5)
Bacterial and Fungal Coinfection in Individuals With Coronavirus: A Rapid Review To Support COVID-19 Antimicrobial Prescribing.
Dexamethasone in Hospitalized Patients with Covid-19
Peter Horby,Wei Shen Lim,Jonathan Emberson,M Mafham,Jennifer L Bell,Louise Linsell,Natalie Staplin,Christopher E. Brightling,Andrew Ustianowski,E Elmahi,B Prudon,Christopher A Green,Timothy Felton,David Chadwick,K Rege,C Fegan,Lucy C Chappell,Saul N. Faust,Thomas Jaki,Katie Jeffery,Alan A Montgomery,Kathryn M Rowan,Edmund Juszczak,J K Baillie,Richard Haynes,Martin J Landray +25 more