Journal ArticleDOI
Incorporation of different antibiotics into carbonated hydroxyapatite coatings on titanium implants, release and antibiotic efficacy.
TLDR
Results suggest that certain antibiotics are able to bind/chelate with calcium, resulting in a better incorporation into the CHA coating and a slower release, which might be used to prevent post-surgical infections and to promote bone-bonding of orthopedic devices.About:
This article is published in Journal of Controlled Release.The article was published on 2004-09-14. It has received 432 citations till now.read more
Citations
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Journal ArticleDOI
Antifouling coatings: recent developments in the design of surfaces that prevent fouling by proteins, bacteria, and marine organisms.
TL;DR: The major strategies for designing surfaces that prevent fouling due to proteins, bacteria, and marine organisms are reviewed and ongoing research in this area should result in the development of even better antifouling materials in the future.
Journal ArticleDOI
Reducing implant-related infections: active release strategies.
TL;DR: This tutorial review focuses on coatings that release antimicrobial agents (i.e., active release strategies) for reducing the incidence of implant-associated infection.
Journal ArticleDOI
The significance of infection related to orthopedic devices and issues of antibiotic resistance.
TL;DR: An overview of the complexity of this battleground and of the current and new, in the opinion most promising, strategies in the field of biomaterials to reduce the risks and counteract the establishment of implant infections is offered.
Journal ArticleDOI
Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review
Susmita Bose,Solaiman Tarafder +1 more
TL;DR: This review highlights some of the current drug and growth factor delivery approaches and critical issues using CaP particles, coatings, cements, and scaffolds towards orthopedic and dental applications.
Journal ArticleDOI
Antibacterial coatings on titanium implants.
TL;DR: A number of approaches have been proposed for rendering the implant surface antibacterial by impeding the formation of a biofilm and they are reviewed in this article.
References
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Journal ArticleDOI
Interactions between Acidic Proteins and Crystals: Stereochemical Requirements in Biomineralization
Lia Addadi,Steve Weiner +1 more
TL;DR: In vitro experiments, in which crystals of calcium dicarboxylate salts were grown in the presence of aspartic acid-rich proteins, revealed a stereochemical property common to all the interacting faces that is important in biomineralization.
Interactions between acidic proteins andcrystals: Stereochemical requirements inbiomineralizatio
L. Addadi,S. WEINERt +1 more
TL;DR: In this article, the authors showed that stereoselective adsorption of an additive onto a specific crystal face results in a drastic decrease in its growth rate relative to that of unaffected faces.
Journal ArticleDOI
Biomimetic Hydroxyapatite Coating on Metal Implants
TL;DR: In this paper, a biomimetic coating was applied on titanium and porous-tantalum implants to facilitate rapid bone formation around the implant, reducing therewith the patient's recovery time after surgery.
Journal ArticleDOI
Influence of ionic strength and carbonate on the Ca-P coating formation from SBF×5 solution
TL;DR: In this article, the authors applied biomimetic calcium-phosphate (Ca-P) coatings on Ti6Al4V by using simulated body fluids concentrated by a factor 5 (SBF×5).
Journal ArticleDOI
Incorporation of tobramycin into biomimetic hydroxyapatite coating on titanium
TL;DR: The result of this study indicates that the biomimetic CHA coatings containing antibiotics could be used to prevent post-surgical infections in orthopaedic or trauma.