Journal ArticleDOI
Influence of Trypanosoma evansi in blood, plasma, and brain cholinesterase of experimentally infected cats.
A. S. da Silva,Roselia Maria Spanevello,Naiara Stefanello,Patrícia Wolkmer,Mateus Matiuzzi da Costa,Régis Adriel Zanette,Sonia Terezinha dos Anjos Lopes,Jânio Morais Santúrio,Maria Rosa Chitolina Schetinger,Silvia Gonzalez Monteiro +9 more
TLDR
The infection by T. evansi influenced cholinesterases of felines indicating changes in the responses of the cholinergic system.About:
This article is published in Research in Veterinary Science.The article was published on 2010-04-01. It has received 30 citations till now. The article focuses on the topics: Trypanosoma evansi & Butyrylcholinesterase.read more
Citations
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Journal ArticleDOI
Outcomes of Trypanosoma cruzi and Trypanosoma evansi infections on health of Southern coati (Nasua nasua), crab-eating fox (Cerdocyon thous), and ocelot (Leopardus pardalis) in the Brazilian Pantanal.
Filipe Martins Santos,Gabriel Carvalho de Macedo,Wanessa Teixeira Gomes Barreto,Luiz Gustavo R. Oliveira-Santos,Carolina Martins Garcia,Guilherme Mourão,Guilherme Mourão,Grasiela Edith de Oliveira Porfírio,Elizangela Domenis Marino,Marcos Rogério André,Lívia Perles,Carina Elisei de Oliveira,Gisele Braziliano de Andrade,Ana Maria Jansen,Ana Maria Jansen,Heitor Miraglia Herrera,Heitor Miraglia Herrera +16 more
TL;DR: Overall, the results indicate that single and combined infection with T. evansi and T. cruzi represent a severe risk to the health of wild carnivores in the Pantanal region.
Journal ArticleDOI
Food web connections and the transmission cycles of Trypanosoma cruzi and Trypanosoma evansi (Kinetoplastida, Trypanosomatidae) in the Pantanal Region, Brazil
Heitor Miraglia Herrera,Heitor Miraglia Herrera,Fabiana Lopes Rocha,Cristiane Varella Lisboa,Vitor Rademaker,Guilherme Mourão,Ana Maria Jansen +6 more
TL;DR: It is proposed that transmission of T. cruzi and T. evansi in the southern Pantanal region takes place via an intricate ecological trophic network involving generalist and specialist mammal species that are linked through a robust food-web connection.
Journal ArticleDOI
Activity of the enzyme adenosine deaminase in serum, erythrocytes and lymphocytes of rats infected with Trypanosoma evansi
Aleksandro Schafer da Silva,Luziane Potrich Bellé,Paula Eliete Rodrigues Bitencourt,Viviane do Carmo Gonçalves Souza,Márcio Machado Costa,Camila B. Oliveira,Jeandre Augusto dos Santos Jaques,Daniela B.R. Leal,Maria Beatriz Moretto,Cinthia M. Mazzanti,Sonia Terezinha dos Anjos Lopes,Silvia Gonzalez Monteiro +11 more
TL;DR: The results showed that the ADA activity was altered in serum, lymphocytes and erythrocytes of rats, concomitantly with haematological parameters, in experimental infection by T. evansi.
Journal ArticleDOI
Acetylcholinesterase activity and lipid peroxidation in the brain and spinal cord of rats infected with Trypanosoma evansi
Aleksandro Schafer da Silva,Silvia Gonzalez Monteiro,Jamile F. Gonçalves,Roselia Maria Spanevello,Camila B. Oliveira,Márcio Machado Costa,Jeandre Augusto dos Santos Jaques,Vera Maria Morsch,Maria Rosa Chitolina Schetinger,Maria Rosa Chitolina Schetinger,Cinthia M. Mazzanti,Sonia Terezinha dos Anjos Lopes +11 more
TL;DR: It is concluded that the changes in AChE activity and lipid peroxidation in the CNS are induced by infection with T. evansi, suggesting that the parasite interferes with the cholinergic neurotransmission in this experimental condition.
Journal ArticleDOI
Trypanosoma evansi: cholinesterase activity in acutely infected Wistar rats.
Patrícia Wolkmer,Sonia Terezinha dos Anjos Lopes,Carina Franciscato,Aleksandro Schafer da Silva,Carolina Kist Traesel,Lucas Carvalho Siqueira,Maria Ester Pereira,Silvia Gonzalez Monteiro,Cinthia M. Mazzanti +8 more
TL;DR: Reductions in the activity of cholinesterase occur in acute infection by T. evansi in rats and this demonstrates an important change occurring in animals infected by the protozoan and may indicate a potential role the enzymes play in the mechanism of disease.
References
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Journal ArticleDOI
Plasma cholinesterase variants and the anaesthetist.
TL;DR: Biochemical properties of plasma cholinesterase of significance to the anaesthetist are reviewed and three new drugs are developed that target these properties.
Journal Article
Acetylcholinesterase and butyrylcholinesterase as possible markers of low-grade systemic inflammation.
TL;DR: Plasma levels of C-reactive protein, interleukin-6, tumor necrosis factor-alpha, and lipid peroxides are high whereas those of endothelial nitric oxide are low in insulin resistance, obesity, type 2 diabetes mellitus, hypertension, hyperlipidemias, metabolic syndrome X, and Alzheimer's disease suggesting that these diseases are characterized by low-grade systemic inflammation.
Journal Article
Effects of early undernutrition on kinetic parameters of brain acetylcholinesterase from adult rats.
TL;DR: It is suggested that early undernutrition changes AChE concentration in cerebellum and striatum and does not affect the affinity of the enzyme for the substrate.
Journal ArticleDOI
Investigations on naturally occurring Trypanosoma evansi infections in horses, cattle, dogs and capybaras (Hydrochaeris hydrochaeris) in Pantanal de Poconé (Mato Grosso, Brazil)
TL;DR: Clinical and parasitological findings support the possible role of the capybara as a reservoir host of T.evansi, dogs and cattle--due to their close contact with horses--should rather be regarded as efficient reservoir hosts for Mal de Cadeiras in the study area.
Journal ArticleDOI
Antisense oligonucleotide inhibition of acetylcholinesterase gene expression induces progenitor cell expansion and suppresses hematopoietic apoptosis ex vivo
Hermona Soreq,Deborah Patinkin,Efrat Lev-Lehman,Mirta Grifman,Dalia Ginzberg,Fritz Eckstein,Haim Zakut +6 more
TL;DR: The findings suggest that the hematopoietic role of acetylcholinesterase, anticipated to be inverse to the observed antisense effects, is to reduce proliferation of the multipotent stem cells committed to erythropoiesis and megakaryocytopoiesi and macrophage production and to promote apoptosis in their progeny.