Journal ArticleDOI
Interaction of C60-Fullerene and Carboxyfullerene with Proteins: Docking and Binding Site Alignment
Hadar Benyamini,Alexandra Shulman-Peleg,Haim J. Wolfson,Bogdan Belgorodsky,Ludmila Fadeev,Michael Gozin +5 more
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TLDR
Docking studies aimed at examining the interactions of fullerenes in two forms with four proteins that are known to bind fullerene derivatives, and provides docking models with detailed binding pockets information, which closely match available experimental data.About:
This article is published in Bioconjugate Chemistry.The article was published on 2006-02-22. It has received 118 citations till now. The article focuses on the topics: Docking (molecular).read more
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Nanomedicine--challenge and perspectives.
Kristina Riehemann,Stefan W. Schneider,Thomas A. Luger,Biana Godin,Mauro Ferrari,Harald Fuchs +5 more
TL;DR: This Review gives an overview of selected recent developments and applications of nanomedicine.
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Chemical Basis of Interactions Between Engineered Nanoparticles and Biological Systems
Qingxin Mu,Guibin Jiang,Lingxin Chen,Hongyu Zhou,Hongyu Zhou,Denis Fourches,Alexander Tropsha,Bing Yan +7 more
TL;DR: As the production and applications of ENMs rapidly expand, their environmental impacts and effects on human health are becoming increasingly significant, and a thorough understanding of how nanomaterials perturb cells and biological molecules is required.
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Nanomaterials in Food and Agriculture: An overview on their safety concerns and regulatory issues
TL;DR: A better understanding of the current scenario of the nanotoxicology, disease progression due to nanomaterials, and their use in the food industry and medical therapeutics is provided.
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Biosafety and Bioapplication of Nanomaterials by Designing Protein–Nanoparticle Interactions
TL;DR: In this article, the current understanding of protein-NP interactions is summarized, including the theoretical background, experimental results, and computational progresses, along with future directions and challenges in this exciting field.
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The Biological Mechanisms and Physicochemical Characteristics Responsible for Driving Fullerene Toxicity
TL;DR: The cellular processes that underlie observed fullerene toxicity will be discussed and include oxidative, genotoxic, and cytotoxic responses and antioxidant/cytoprotective properties of fullerenes have been considered and encourage their utilization within the treatment of oxidant-mediated disease.
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Clustal w: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
TL;DR: The sensitivity of the commonly used progressive multiple sequence alignment method has been greatly improved and modifications are incorporated into a new program, CLUSTAL W, which is freely available.
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C 60 : Buckminsterfullerene
Harold W. Kroto,Harold W. Kroto,James R. Heath,Sean C. O'Brien,Robert F. Curl,Richard E. Smalley +5 more
TL;DR: In this article, the authors proposed a truncated icosahedron, a polygon with 60 vertices and 32 faces, 12 of which are pentagonal and 20 hexagonal.
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Inhibition of the HIV-1 protease by fullerene derivatives: model building studies and experimental verification
TL;DR: The ability of C[sub 60] fullerene derivatives to interact with the active site of HIV-1 protease (HIVP) has been examined through model building and simple physical chemical analysis as discussed by the authors.
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Fullerene derivatives: an attractive tool for biological applications
TL;DR: Fullerene is able to fit inside the hydrophobic cavity of HIV proteases, inhibiting the access of substrates to the catalytic site of the enzyme, and can be used as radical scavenger and singlet oxygen in high quantum yields.
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Photoinduced biochemical activity of fullerene carboxylic acid
TL;DR: It is found that even low-energy visible light is surfficient to induce biological activity in fullerene derivatives, suggesting that fullerenes may serve as useful photosensitive biochemical probes.