Journal ArticleDOI
Interactions between membranes and cytolytic peptides.
Alan W. Bernheimer,Bernardo Rudy +1 more
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The manner in which cytolytic peptides interact with plasma membranes of eukaryotic cells, particularly the membranes of erythrocytes, has been discussed with emphasis on melittin, thiolactivated lysins and staphylococcal alpha-toxin.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1986-06-12. It has received 301 citations till now. The article focuses on the topics: Aerolysin & Lysin.read more
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The amphipathic helix in the exchangeable apolipoproteins: a review of secondary structure and function.
Jere P. Segrest,Martin K. Jones,H De Loof,Christie G. Brouillette,Y. V. Venkatachalapathi,Gattadahalli M. Anantharamaiah +5 more
TL;DR: It is of particular interest, therefore, that all of the exchangeable apolipoproteins except apoA-II and C-I, contain amphipathic helixes of class G*.
Journal ArticleDOI
The actions of melittin on membranes.
TL;DR: Despite the structural complexity of integral membrane proteins, it is interesting that in some respects their study be more straightforward, lacking as they do the elusive properties of melittin which limit the possibility of defining their interaction with membranes in terms of a single conformation, location, orientation and association state within the membrane.
Journal ArticleDOI
Amphipathic helix motif: Classes and properties
Jere P. Segrest,H De Loof,Jan G. Dohlman,Christie G. Brouillette,Gattadahalli M. Anantharamaiah +4 more
Journal ArticleDOI
Melittin : a membrane-active peptide with diverse functions
TL;DR: The solution and membrane properties ofmelittin are highlighted, with an emphasis on melittin–membrane interaction using biophysical approaches, and the recent applications of melitt in various cellular processes are discussed.
Journal ArticleDOI
Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion.
Cynthia L. Sears,James B. Kaper +1 more
TL;DR: The role of Shiga-like toxin I in bacterial enteritis: comparison between isogenic Esch- erichia coli strains induced in rabbits and new live attenuated chol- era vaccines is compared.
References
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Journal ArticleDOI
Amphiphilic secondary structure: design of peptide hormones.
ET Kaiser,FJ Kezdy +1 more
TL;DR: This work has shown that when models are designed to optimize the amphiphilicity of the secondary structure, stronger interactions can be observed with the synthetic peptides than with the naturally occurring analogs.
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Vibrio Parahaemolyticus and Related Halophilic Vibrios
TL;DR: The relationship of this organism to the environment reveals a close association with other marine organisms especially copepods on which the Vibrios depend for survival in winter months and growth in summer months and a uniquely provocative disparity between human strains of V. parahaemolyticus.