Journal ArticleDOI
Investigating the feasibility of temperature-controlled accelerated drug release testing for an intravaginal ring.
TLDR
Results from this study indicate that changes in the polymeric structure can lead to a different temperature dependence of the release rate, and as a consequence, the accelerated method can become less sensitive to detect changes inThe release properties.About:
This article is published in European Journal of Pharmaceutics and Biopharmaceutics.The article was published on 2013-11-01. It has received 22 citations till now. The article focuses on the topics: Dosage form.read more
Citations
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Journal ArticleDOI
Applications of ethylene vinyl acetate copolymers (EVA) in drug delivery systems
TL;DR: This review examines the breadth of EVA use in drug delivery, and will aid the researcher in locating key references and experimental results, as well as understanding the features ofEVA as a highly versatile, biocompatible polymer for drug delivery devices.
Journal ArticleDOI
Zero-order drug delivery: State of the art and future prospects.
TL;DR: Zero-order drug delivery systems have the potential to overcome the issues facing immediate-release and first-order systems by releasing drug at a constant rate, thereby maintaining drug concentrations within the therapeutic window for an extended period of time.
Journal ArticleDOI
An overview of in vitro dissolution/release methods for novel mucosal drug delivery systems.
Mario Jug,Anita Hafner,Jasmina Lovrić,Maja Lusina Kregar,Ivan Pepić,Željka Vanić,Biserka Cetina-Čižmek,Jelena Filipović-Grčić +7 more
TL;DR: A comprehensive review of both compendial and noncompendial methods used for in vitro dissolution/release testing of novel mucosal drug delivery systems aimed for ocular, nasal, oromucosal, vaginal and rectal administration is provided.
Journal ArticleDOI
Biodegradable Polymeric Injectable Implants for Long-Term Delivery of Contraceptive Drugs.
Ohan S. Manoukian,Michael R. Arul,Naseem Sardashti,Teagan Stedman,Roshan James,Swetha Rudraiah,Sangamesh G. Kumbar +6 more
TL;DR: The inclusion of multiple elevated release temperatures allowed for the application of the Arrhenius model to calculate drug release constants and representative sampling intervals, demonstrating the use of elevated temperatures for accelerated-time drug release studies.
Journal ArticleDOI
Recent progress in continuous and semi-continuous processing of solid oral dosage forms: a review
TL;DR: The attempt to connect the primary and secondary production steps proves that development of continuously operating lines is possible and a mind-set change is needed to be able to face, and fully assess, the advantages and disadvantages of switching from batch to continuous mode production.
References
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Journal ArticleDOI
Transport phenomena through polymeric systems
Soney C. George,Sabu Thomas +1 more
TL;DR: A detailed review of current research in the field of transport phenomena and membrane assisted transport processes is provided in this paper, where the relationships between membrane characteristics, polymer structure and separation efficacy are treated in detail.
Book
Controlled Release of Biologically Active Agents
TL;DR: Principles of Membrane Diffusion Diffusion- Controlled Systems Biodegradable Systems Osmotic and Mechnical Devices Materials used in Controlled Release Devices Device Preparation and Evaluation Applications and the Future Index are presented.
Book
Novel Drug Delivery Systems
TL;DR: Concepts and System Design for the Rate-Controlled Drug Delivery Fundamentals of Rate-Control Drug Delivery Oral Drug Delivery and Delivery Systems Mucosal Drug Delivery: Potential Routes for Noninvasive Systemic Administration and Regulatory Considerations in Controlled Drug Delivery.
Journal ArticleDOI
A vaginal fluid simulant.
Derek H. Owen,David F. Katz +1 more
TL;DR: A fluid medium was developed to simulate the fluid produced in the human vagina, and properties that influence interactions of vaginal fluid with topical contraceptive, prophylactic, or therapeutic products were emphasized.
BookDOI
Novel Drug Delivery Systems, Second Edition,
TL;DR: In this article, the basic concepts and system design for rate-controlled drug delivery are presented. Butterfield et al. discuss the potential routes for noninvasive systemic administration for non-invasive drug administration.