Knee osteoarthritis phenotypes and their relevance for outcomes: a systematic review
TLDR
Evidence is found suggesting that pain sensitization, psychological distress, radiographic severity, body mass index (BMI), muscle strength, inflammation and comorbidities are associated with clinically distinct phenotypes.About:
This article is published in Osteoarthritis and Cartilage.The article was published on 2017-12-01 and is currently open access. It has received 199 citations till now.read more
Citations
More filters
Journal ArticleDOI
Epidemiology of osteoarthritis: literature update.
Ernest R. Vina,C. Kent Kwoh +1 more
TL;DR: This review highlights recent studies of osteoarthritis epidemiology, including research on prevalence, disease impact, and potential risk factors, which may allow us to develop innovative strategies and novel therapies for preventing new disease onset and minimizing disease progression.
Journal ArticleDOI
Chondrocyte dedifferentiation and osteoarthritis (OA)
Edith Charlier,Céline Deroyer,Federica Ciregia,Olivier Malaise,Sophie Neuville,Zelda Plener,Michel Malaise,Dominique de Seny +7 more
TL;DR: Molecular knowledge underlying dedifferentiation process is presented, connections between dedifferentiated-like and OA are emphasized and therapeutic strategies aiming at the maintenance of chondrogenic phenotype are considered.
Journal ArticleDOI
Osteoarthritis phenotypes and novel therapeutic targets.
TL;DR: It is suggested that combining patient clinical data, quantitative imaging, biochemical markers and utilizing data-driven approaches in patient selection and efficacy assessment will allow for more successful development of effective DMOADs.
Journal ArticleDOI
Effects of Physical Activity in Knee and Hip Osteoarthritis: A Systematic Umbrella Review.
Virginia B. Kraus,Kyle Sprow,Kenneth E. Powell,David M. Buchner,Bonny Bloodgood,Katrina L. Piercy,Stephanie M. George,William E. Kraus +7 more
TL;DR: People with lower-extremity OA should be encouraged to engage in achievable amounts of physical activity, of even modest intensities, and be confident in gaining some health and arthritis-related benefits.
Journal ArticleDOI
Is osteoarthritis one disease or a collection of many
TL;DR: An updated summary of the most recent advances in the identification of meaningful OA phenotypes as well as limitations from previous approaches that can be addressed in future studies are provided.
References
More filters
Journal Article
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
TL;DR: The QUOROM Statement (QUality Of Reporting Of Meta-analyses) as mentioned in this paper was developed to address the suboptimal reporting of systematic reviews and meta-analysis of randomized controlled trials.
Journal ArticleDOI
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
TL;DR: PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) is introduced, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses.
Journal ArticleDOI
The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions.
Sara H. Downs,Nick Black +1 more
TL;DR: It is shown that it is feasible to develop a checklist that can be used to assess the methodological quality not only of randomised controlled trials but also non-randomised studies and it is possible to produce a Checklist that provides a profile of the paper, alerting reviewers to its particular methodological strengths and weaknesses.
Journal ArticleDOI
Evaluating non-randomised intervention studies.
Jonathan J Deeks,Jacqueline Dinnes,Roberto D'Amico,Amanda Sowden,C Sakarovitch,Fujian Song,Mark Petticrew,Douglas G. Altman +7 more
TL;DR: The inability of case-mix adjustment methods to compensate for selection bias and the inability to identify non- randomised studies that are free of selection bias indicate that non-randomised studies should only be undertaken when RCTs are infeasible or unethical.
Journal ArticleDOI
Evidence of sensorimotor deficits in functional ankle instability: a systematic review with meta-analysis.
TL;DR: When subjects with unstable ankles were compared to healthy controls, sensorimotor impairments were demonstrated for passive joint position sense and postural control in subjects with FAI and peroneal reaction time was not affected.
Related Papers (5)
Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee
Roy D. Altman,E. Asch,Daniel Bloch,Giles G. Bole,David G. Borenstein,Kenneth D. Brandt,Wallace C. Christy,Cooke Td,Robert A. Greenwald,Marc C. Hochberg,David S. Howell,David L. Kaplan,William J. Koopman,Selden Longley,Henry J. Mankin,Dennis J. McShane,Thomas A. Medsger,Robert F. Meenan,William M. Mikkelsen,Roland W. Moskowitz,William A. Murphy,B. Rothschild,Mark R. Segal,Leon Sokoloff,Frederick Wolfe +24 more
The global burden of hip and knee osteoarthritis: estimates from the Global Burden of Disease 2010 study
OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis
Raveendhara R. Bannuru,Mikala C. Osani,Elizaveta E. Vaysbrot,Nigel K Arden,Nigel K Arden,Kim L Bennell,Sita M A Bierma-Zeinstra,Virginia B. Kraus,L.S. Lohmander,J.H. Abbott,Mohit Bhandari,Francisco J. Blanco,R. Espinosa,Ida K. Haugen,J. Lin,Lisa A. Mandl,Eeva Moilanen,Norimasa Nakamura,Lynn Snyder-Mackler,Thomas H. Trojian,Malcolm J. Underwood,Malcolm J. Underwood,Timothy E. McAlindon +22 more