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KNIME: The Konstanz Information Miner.

TLDR
Some of the design aspects of the underlying architecture of the Konstanz Information Miner are described and briefly sketch how new nodes can be incorporated.
Abstract
The Konstanz Information Miner is a modular environment, which enables easy visual assembly and interactive execution of a data pipeline. It is designed as a teaching, research and collaboration platform, which enables simple integration of new algorithms and tools as well as data manipulation or visualization methods in the form of new modules or nodes. In this paper we describe some of the design aspects of the underlying architecture and briefly sketch how new nodes can be incorporated.

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Citations
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Big Data: A Survey

TL;DR: The background and state-of-the-art of big data are reviewed, including enterprise management, Internet of Things, online social networks, medial applications, collective intelligence, and smart grid, as well as related technologies.
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A new bioinformatics analysis tools framework at EMBL–EBI

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References
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The Chemistry Development Kit (CDK): An open-source Java library for chemo- and bioinformatics

TL;DR: The Chemistry Development Kit provides methods for many common tasks in molecular informatics, including 2D and 3D rendering of chemical structures, I/O routines, SMILES parsing and generation, ring searches, isomorphism checking, structure diagram generation, etc.

Parallel and Distributed Data Pipelining with KNIME

TL;DR: The parallel and distribution potential of pipelining tools is discussed by demonstrating several parallel and distributed implementations in the open source pipeline platform KNIME and verifying the practical applicability in a number of real world experiments.