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Journal ArticleDOI

Label-free G-quadruplex-specific fluorescent probe for sensitive detection of copper(II) ion

TLDR
This probe provided an effective platform for reliable detection of Cu(2+) with a detection limit as low as 3.0nM, the high sensitivity was attributed to the strong metalation of PPIX with Cu( 2+) catalyzed by G-quadruplex (PS5.M).
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This article is published in Biosensors and Bioelectronics.The article was published on 2013-01-15. It has received 69 citations till now. The article focuses on the topics: Fluorescence & Protoporphyrin IX.

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Citations
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Metal nanoclusters: New fluorescent probes for sensors and bioimaging

TL;DR: In this paper, the authors focus on recent advances in controllable synthesis strategies, chemical and optical properties, and sensing and imaging applications of metal nanoclusters (mainly including Au, Ag, Cu, etc.).
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Carbon dots as fluorescent probes for "off-on" detection of Cu2+ and L-cysteine in aqueous solution.

TL;DR: An "off-on" approach for highly sensitive and selective detection of Cu(2+) and L-Cys using carbon dots (CDs) as fluorescent probes using mesoporous silica spheres as nanoreactors is demonstrated, which is promising for biological applications.
Journal ArticleDOI

Recent Developments in G-Quadruplex Probes

TL;DR: This review highlights examples of G-quadruplex probes that have been reported over the last few years, some of which have been employed for cellular imaging or for use in the construction ofG- quadruplex-based analytical sensing platforms.
Journal ArticleDOI

G-quadruplexes for luminescent sensing and logic gates.

TL;DR: This Survey and Summary highlights recent examples of the application of the label-free strategy for the development of G-quadruplex-based luminescent detection platforms with a view towards the potential application of tetraplex structures in the design of DNA logic gates.
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Colorimetric and fluorescent chemosensors for Cu2+. A comprehensive review from the years 2013–15

TL;DR: In this article, a review of selective and sensitive Cu2+ ion detection achieved by various receptor types in the years between 2013 to 2015 is presented. But the focus of this review was not on the detection of metal ions.
References
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Journal ArticleDOI

Helix Formation by Guanylic Acid

TL;DR: From examination of the optical properties of the gel and investigation of the structure of fibers obtained from the gel by drying, it is concluded that, at least in the case of the 5' isomer, the phenomenon may be explained as being due to helix formation by the guanylic acid.
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A DNAzyme catalytic beacon sensor for paramagnetic Cu2+ ions in aqueous solution with high sensitivity and selectivity.

TL;DR: A highly sensitive and selective “turn-on” fluorescent Cu2+ sensor based on an in vitro selected DNAzyme that has a detection limit of 35 nM and a dynamic range up to 20 μM and more than 2000-fold selectivity.
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Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo

TL;DR: RNA interference is used to explore in vivo functions of two ciliate TEBPs, TEBPα and TEBPβ, and shows that they cooperate to control the formation of an antiparallel guanine quadruplex DNA structure at telomeres in vivo.
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Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA

TL;DR: It is shown that intracellular transcription of G-rich regions produces novel DNA structures, visible by electron microscopy as large G-loops formed cotranscriptionally, and they contain G4 DNA on one strand and a stable RNA/DNA hybrid on the other.
Journal ArticleDOI

Visual Detection of Copper(II) by Azide- and Alkyne-Functionalized Gold Nanoparticles Using Click Chemistry

TL;DR: This method allows the naked eye, without the aid of any advanced instrument, to assay for the presence of Cu ions by the aggregation of Au NPs as a result of the Cu(I)-catalyzed conjugation between the two functional groups.
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