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Leucocyte typing V. White cell differentiation antigens
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The article was published on 1995-01-01 and is currently open access. It has received 259 citations till now. The article focuses on the topics: Typing.read more
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Mesenchymal progenitor cells in human umbilical cord blood.
TL;DR: The results suggest that preterm, as compared with term, cord blood is richer in mesenchymal progenitors, similar to haematopoietic progenitor cells.
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A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them
TL;DR: In this paper, the authors provide definitive evidence for transcellular (i.e., through individual endothelial cells) diapedesis in vitro and demonstrate that virtually all, both para-and trans-cellular, diapedis occurred in the context of a novel "cuplike" transmigratory structure.
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Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions
Ayumi Yoshizaki,Tomomitsu Miyagaki,David J. DiLillo,Takashi Matsushita,Mayuka Horikawa,Evgueni I. Kountikov,Rosanne Spolski,Jonathan C. Poe,Warren J. Leonard,Thomas F. Tedder +9 more
TL;DR: It is shown that B10-cell maturation into functional IL-10-secreting effector cells that inhibit in vivo autoimmune disease requires IL-21 and CD40-dependent cognate interactions with T cells, and that the ex vivo expansion and reinfusion of autologous B10 cells may provide a novel and effective in vivo treatment for severe autoimmune diseases that are resistant to current therapies.
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Human reserve pluripotent mesenchymal stem cells are present in the connective tissues of skeletal muscle and dermis derived from fetal, adult, and geriatric donors.
Henry E. Young,Timothy A. Steele,Timothy A. Steele,Robert A. Bray,John A. Hudson,Julie A. Floyd,Kristina C. Hawkins,Karen Thomas,Troy Austin,Chris Edwards,Jeremy Cuzzourt,Mary Duenzl,Paul A. Lucas,Asa C. Black +13 more
TL;DR: This study details the profile of 13 cell surface cluster differentiation markers on human reserve stem cells derived from connective tissues as well as lineage‐uncommitted pluripotent stem cells capable of forming muscle, adipocytes, cartilage, bone, fibroblasts, and endothelial cells.
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CD80 (B7-1) Binds Both CD28 and CTLA-4 with a Low Affinity and Very Fast Kinetics
TL;DR: In this paper, the authors used surface plasmon resonance to measure the affinity and kinetics of CD80 binding to CD28 and CTLA-4, and showed that these low affinities were the result of very fast dissociation rate constants (k(off)).