Journal ArticleDOI
Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
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This article is published in Cell.The article was published on 1994-01-28. It has received 7128 citations till now. The article focuses on the topics: Leukocyte adhesion molecule.read more
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Wound Healing--Aiming for Perfect Skin Regeneration
TL;DR: Details of how these signals control wound cell activities are beginning to emerge, and studies of healing in embryos have begun to show how the normal adult repair process might be readjusted to make it less like patching up and more like regeneration.
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Chemokines — Chemotactic Cytokines That Mediate Inflammation
TL;DR: This review introduces the burgeoning family of cytokines, with special emphasis on their role in the pathophysiology of disease and their potential as targets for therapy.
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Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis
TL;DR: A coupling between physical adhesion and developmental signaling provides a mechanism to tightly integrate physical aspects of tissue morphogenesis with cell growth and differentiation, a coordination that is essential to achieve the intricate patterns of cells in tissues.
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The importance of the ratio of omega-6/omega-3 essential fatty acids.
TL;DR: In this article, a lower omega-6/omega-3 ratio in women with breast cancer was associated with decreased risk, whereas a higher ratio of omega-3 PUFA had no effect.
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The Immunological Synapse: A Molecular Machine Controlling T Cell Activation
Arash Grakoui,Shannon K. Bromley,Cenk Sumen,Mark M. Davis,Andrey S. Shaw,Paul M. Allen,Michael L. Dustin +6 more
TL;DR: Immunological synapse formation is now shown to be an active and dynamic mechanism that allows T cells to distinguish potential antigenic ligands and was a determinative event for T cell proliferation.
References
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Adhesion receptors of the immune system.
TL;DR: Three families of cell-surface molecules regulate the migration of lymphocytes and the interactions of activated cells during immune responses.
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Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity
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Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins
TL;DR: Rolling of leukocytes on vascular endothelial cells, an early event in inflammation, can be reproduced in vitro on artificial lipid bilayers containing purified CD62, a selectin also named PADGEM and GMP-140 that is inducible on endothelial Cells.
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Properties of the Novel Proinflammatory Supergene "Intercrine" Cytokine Family
TL;DR: This review has summarized and discussed the available information concerning the regulation and structure of the genes, the structure and biochemical properties of the polypeptide products, their receptors, signal transduction, cell sources, and in vitro as well as in vivo activities of these cytokines.
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VLA proteins in the integrin family : structures, functions and their role on leukocytes
TL;DR: Article de synthese sur les roles des integrines β1 (proteines VLA) comme recepteurs dans l'adherence des leucocytes a la matrice extracellulaire and comme envelopes dans leherence cellule a cellule.