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Longitudinal and cross-sectional effects of C-reactive protein, equilibrated normalized protein catabolic rate, and serum bicarbonate on creatinine and albumin levels in dialysis patients

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TLDR
In this article, the authors analyzed albumin and creatinine levels as outcome variables and their association with C-reactive protein (CRP), equilibrated normalized protein catabolic rate (enPCR), and serum bicarbonate level as independent variables from laboratory data obtained from patients in the Hemodialysis Study.
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This article is published in American Journal of Kidney Diseases.The article was published on 2003-12-01. It has received 100 citations till now. The article focuses on the topics: Serum albumin & Creatinine.

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Journal ArticleDOI

Serum albumin: relationship to inflammation and nutrition.

TL;DR: In this paper, the combined effects of inflammation and inadequate protein and caloric intake in patients with chronic disease such as chronic renal failure were identified as the cause of hypoalbuminemia.
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EBPG Guideline on Nutrition

TL;DR: Recommendations for vitamins,minerals and trace elementsadministration in maintenancehaemodialysis patients and other interventions: daily dialysis, oral supplements and enteral feeding.
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Association between serum albumin and mortality in dialysis patients is partly explained by inflammation, and not by malnutrition.

TL;DR: In dialysis patients, a 1-g/dL decrease in serum albumin was associated with an increased mortality risk of 47% in HD patients and 38% in PD patients, and these mortality risks were in part explained by the inflammatory pathway.
Journal ArticleDOI

Association of predialysis serum bicarbonate levels with risk of mortality and hospitalization in the Dialysis Outcomes and Practice Patterns Study (DOPPS)

TL;DR: Moderate predialysis acidosis seems to be associated with better nutritional status and lower relative risk for mortality or hospitalization than is observed in patients with normal ranges of midweekpredialysis serum bicarbonate concentration or severe acidosis.
References
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Journal ArticleDOI

Generalized Additive Models.

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Analysis of longitudinal data

TL;DR: In this paper, a generalized linear model for longitudinal data and transition models for categorical data are presented. But the model is not suitable for categric data and time dependent covariates are not considered.
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C-Reactive Protein, a Sensitive Marker of Inflammation, Predicts Future Risk of Coronary Heart Disease in Initially Healthy Middle-Aged Men Results From the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992

TL;DR: These results confirm the prognostic relevance of CRP, a sensitive systemic marker of inflammation, to the risk of CHD in a large, randomly selected cohort of initially healthy middle-aged men and suggest that low-grade inflammation is involved in pathogenesis of atherosclerosis, especially its thrombo-occlusive complications.
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Death Risk in Hemodialysis Patients: The Predictive Value of Commonly Measured Variables and an Evaluation of Death Rate Differences Between Facilities

TL;DR: Strategies designed to improve the overall mortality statistic for dialysis patients in the United States would be better directed toward improving the quality of care for all patients, particularly high-risk patients, within their usual treatment settings rather than trying to identify facilities with high death rate for possible regulatory intervention.
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