Journal ArticleDOI
Mechanism of formation of pseudotypes between vesicular stomatitis virus and murine leukemia virus.
Owen N. Witte,David Baltimore +1 more
TLDR
Results suggest that small numbers of VSV G protein are obligately incorporated into VSV(MuLV) pseudotypes, and there appears to be a stringent requirement for recognition of the viral core by homologous envelope components as the nucleating step in the budding process.About:
This article is published in Cell.The article was published on 1977-07-01. It has received 78 citations till now. The article focuses on the topics: Vesicular stomatitis virus & Murine leukemia virus.read more
Citations
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Journal ArticleDOI
Cell Surface Polarity in Epithelia
Kai Simons,S D Fuller +1 more
TL;DR: Systemes experimentaux pour etudier la biogenese de la surface cellulaire, organisation moleculaire de the surface de the cellule epitheliale, d'endocytose et transcytose, et insertion des proteines membranaires.
Book ChapterDOI
Generation of high-titer pseudotyped retroviral vectors with very broad host range.
TL;DR: In this article, a pseudotyped version of a retrovirus was found to integrate into the genome of a single cell when a high multiplicity of infection was used to infect the cells.
Journal ArticleDOI
Virus Maturation by Budding
TL;DR: It is proposed that the budding of enveloped viruses in general is governed by lateral interactions between peripheral or integral membrane proteins, which has implications for the mechanism by which the virion is uncoated during virus entry.
Journal ArticleDOI
Pseudotype formation of murine leukemia virus with the G protein of vesicular stomatitis virus
TL;DR: Results show that VSV G protein can be incorporated into the virions of retrovirus in the absence of other VSV-encoded proteins or of Retroviral envelope protein.
Journal ArticleDOI
Generation of VSV pseudotypes using recombinant ΔG-VSV for studies on virus entry, identification of entry inhibitors, and immune responses to vaccines.
TL;DR: These protocols should allow any laboratory knowledgeable in general virological and cell culture techniques to produce successfully replication-restricted rVSV-ΔG pseudotypes for subsequent analysis.
References
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Journal ArticleDOI
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products.
Journal Article
Cleavage of structural proteins during the assemble of the head of bacterio-phage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products as mentioned in this paper.
Journal ArticleDOI
The glycoprotein of vesicular stomatitis virus is the antigen that gives rise to and reacts with neutralizing antibody
TL;DR: The glycoprotein, but no other virion protein, of vesicular stomatitis virus was solubilized by the nonionic detergent Triton X-100 in low ionic strength buffer and induced the synthesis of antibody that formed a single precipitin line with the glycop protein and neutralized the infectivity of the virus.
Journal ArticleDOI
The membrane structure of lipid-containing viruses.
John Lenard,Richard W. Compans +1 more
Journal ArticleDOI
gag Gene of mammalian type-C RNA tumour viruses
TL;DR: The translation product of the gag gene of mammalian type-C RNA viruses is a 65,000–68,000 molecular weight precursor polypeptide whose cleavage leads to the formation of four virion proteins, p30, p15, p12 and p10.