Journal ArticleDOI
Membrane flow and interconversions among endomembranes
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TLDR
The results obtained allowed us to assess the importance of knowing the carrier and removal status of canine coronavirus, as a source of infection for other animals, not necessarily belonging to the same breeds.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1979-04-23. It has received 271 citations till now. The article focuses on the topics: Exocytosis & Endomembrane system.read more
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Journal ArticleDOI
The trans Golgi Network: Sorting at the Exit Site of the Golgi Complex
Gareth Griffiths,Kai Simons +1 more
TL;DR: A model is proposed whereby three different classes of proteins are sorted into different vesicles in the last Golgi compartment, the trans Golgi network, which corresponds to a tubular reticulum on the trans side of the Golgi stack.
Journal ArticleDOI
Exfoliation of membrane ecto-enzymes in the form of micro-vesicles
TL;DR: It was concluded that the shedded vesicles constituted a select portion of the plasma membrane and may serve a physiologic function; it is proposed that they be referred to as exosomes.
BookDOI
The Influenza viruses
TL;DR: Among the most significant accomplish ments in influenza virus research has been the delineation of the three dimensional structure of the two surface glycoproteins of the virus, the hemagglutinin and neuraminidase, which provided a structural basis for mapping both the antigenic sites and the regions involved in the major biological functions of these two molecules.
Journal ArticleDOI
Pre- and post-Golgi vacuoles operate in the transport of Semliki Forest virus membrane glycoproteins to the cell surface.
Jaakko Saraste,Esa Kuismanen +1 more
TL;DR: The effect of reduced temperature on synchronized transport of SFV membrane proteins from the ER via the Golgi complex to the surface of BHK-21 cells revealed two membrane compartments where transport could be arrested, and it is proposed that membrane proteins enter the Gol Gi stack via tubular extensions of the pre-Golgi vacuolar elements which generate the GolGI cisternae.
Journal ArticleDOI
The golgi apparatus: two organelles in tandem.
TL;DR: The Golgi apparatus consists of distinct cis and trans compartments that may act sequentially to refine the protein export of the endoplasmic reticulum by removing escaped endoplasmsic Reticulum proteins.
References
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Journal ArticleDOI
Intracellular aspects of the process of protein synthesis
TL;DR: The title of the Nobel Lecture of George Palade (1 August, p. 347) should have been "Intracellular aspects of the process of protein secretion."
Journal Article
Pharmacological implications of microsomal enzyme induction
TL;DR: It is of considerable interest that certain inducers of liver microsomal enzymes have recently been used therapeutically for the treatment of hyperbilirubinemia in jaundiced children and for thetreatment of Cushing's syndrome.
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Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.
TL;DR: In this article, it was shown that in vitro completion of these nascent light chains resulted in the synthesis of some chains having the same mol wt as the authentic secreted light chain, because of completion of in vivo proteolytically processed chains and of other chains which, due to the completion of unprocessed chains, have the same moll wt, as the precursor of the light chain.
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Evidence for recycling of synaptic vesicle membrane during transmitter release at the frog neuromuscular junction
John E. Heuser,Thomas S. Reese +1 more
TL;DR: During stimulation the intracellular compartments of this synapse change shape and take up extracellular protein in a manner which indicates that synaptic vesicle membrane added to the surface during exocytosis is retrieved by coated vesicles and recycled into new synaptic vESicles by way of intermediate cisternae.