Journal ArticleDOI
Mental impairment in unilateral frontal tumours: role of the laterality of the lesion
TLDR
Right frontal lobe tumours were found to raise spirits and led to euphoria, underestimation of one's disorder and full anosognosia, loss of critical faculty, attention instability and distractibility.Abstract:
Seventy-two patients with left frontal lobe tumours and 68 patients with right frontal lobe tumours were studied clinically and experimentally. Left frontal lobe tumours were consistent with poorer motor and mimical activity, speech disturbances, manifested as efferent motor or dynamic aphasia, slowing down of the tempo of mental processes, deterioration of verbal memory, reduced generalization ability, difficulties in attention shifting and stereotyped thinking. In mild cases, the above impairments were associated with depressed feelings, in advanced cases with apathico-abulic syndrome. Right frontal lobe tumours were found to raise spirits and led to euphoria, underestimation of one's disorder and full anosognosia, loss of critical faculty, attention instability and distractibility. Development of mental disorders in left-sided frontal tumours mainly depends on tumour localization, while in right-sided ones tumour size and malignancy are the determining factors.read more
Citations
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Treatment of depression with transcranial direct current stimulation (tDCS): a review.
TL;DR: Application of the newly developed stimulation protocols in patients with major depression has shown promise in few pilot studies, but further studies are needed to identify the optimal parameters of stimulation and the clinical and patient characteristics that may condition response to tDCS.
Journal ArticleDOI
Affective disorders and cerebral vascular disease.
TL;DR: Post-stroke mania is strongly associated with both a right hemisphere lesion in a limbic-connected area and a second predisposing factor, such as genetic loading for affective disorder, pre-existing subcortical atrophy or seizure disorder, which may be mediated through frontal lobe dysfunction.
Journal ArticleDOI
Anosognosia in Alzheimer's disease: Relationships to depression, cognitive function, and cerebral perfusion
TL;DR: There is further evidence that dementia severity alone does not account for anosognosia in Alzheimer's disease; frontal lobe involvement and the presence of specific memory impairments may be important determining factors.
Journal ArticleDOI
Preoperative and postoperative cognitive functioning in patients with frontal meningiomas.
TL;DR: Comparisons of pre- and postoperative assessments of cognition revealed no differences in memory, visuoconstructive abilities, or executive functions, although a postoperative improvement in attentional functions was observed.
Journal ArticleDOI
Medial and lateral networks in anterior prefrontal cortex support metacognitive ability for memory and perception
TL;DR: The results suggest that an individual's capacity for accurate introspection in the domains of perception and memory is related to the functional integrity of unique neural networks anchored in the medial and lateral regions of the aPFC.
References
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Journal ArticleDOI
Differential behavioral effects in frontal lobe disease
TL;DR: In this article, the performances of groups of patients with left, right and bilateral frontal lesions were compared on a battery consisting of two tests presumed to be related specifically to left hemisphere function, another test presumed to relate to right hemisphere function and another test related to bilateral frontal lobe function.
Journal ArticleDOI
Some cognitive effects of frontal-lobe lesions in man.
TL;DR: After frontal lobectomy in either hemisphere, deficits are found quite consistently on motor-differentiation tasks (Konorski 1972) in which the subject must learn to produce different responses to different, randomly presented, environmental signals.
Journal Article
[Respective rôles of frontal lesions and lesion lateralization in "verbal fluency" deficiencies].
Ramier Am,Hecaen H +1 more
Journal ArticleDOI
Intellectual impairment with localized cerebral lesions.
J. Mcfie,M. F. Pjercy +1 more
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