Daniel S. Margulies

TL;DR: The 1000 Functional Connectomes Project (Fcon_1000) as discussed by the authors is a large-scale collection of functional connectome data from 1,414 volunteers collected independently at 35 international centers.

TL;DR: An overarching organization of large-scale connectivity that situates the default-mode network at the opposite end of a spectrum from primary sensory and motor regions is described, suggesting that the role of the DMN in cognition might arise from its position at one extreme of a hierarchy, allowing it to process transmodal information that is unrelated to immediate sensory input.

TL;DR: This work provides a comprehensive functional connectivity analysis of basal ganglia circuitry in humans through a functional magnetic resonance imaging examination during rest and revealed subtler distinctions within striatal subregions not previously appreciated by task-based imaging approaches.

TL;DR: The findings provide a solid foundation for continued examination of resting state fcMRI in typical and atypical populations, and short- and long-term measures of the consistency of global connectivity patterns were highly robust.

TL;DR: These subdivisions within the precuneus suggest that neuroimaging studies will benefit from treating this region as anatomically (and thus functionally) heterogeneous, and provide support that resting-state functional connectivity (RSFC) may in part reflect underlying anatomy.