Journal ArticleDOI
Metabolism of phenolic acids by the rat intestinal microflora.
About:
This article is published in Pharmacology & Toxicology.The article was published on 2009-03-13. It has received 155 citations till now.read more
Citations
More filters
Journal ArticleDOI
Chlorogenic acid and caffeic acid are absorbed in humans.
TL;DR: One third of chlorogenic acid and almost all of the caffeic acid were absorbed in the small intestine of humans, which implies that part ofchlorogenic acid from foods will enter into the blood circulation, but most will reach the colon.
Journal ArticleDOI
Chemistry, natural sources, dietary intake and pharmacokinetic properties of ferulic acid: A review
TL;DR: The absorption and metabolism of FA seem to be dose dependent at least in experimental settings, and further pharmacokinetic and pharmacodynamic studies are required to characterize the impact of FA on human health.
Journal ArticleDOI
Chlorogenic Acid Bioavailability Largely Depends on Its Metabolism by the Gut Microflora in Rats
TL;DR: A high abundance of microbial metabolites shows that the bioavailability of chlorogenic acid depends largely on its metabolism by the gut microflora, and their potential importance in explaining the biological effects of dietary polyphenols is emphasized.
Journal ArticleDOI
Biosynthesis, natural sources, dietary intake, pharmacokinetic properties, and biological activities of hydroxycinnamic acids
Hesham R. El-Seedi,Hesham R. El-Seedi,Asmaa M. A. El-Said,Shaden A. M. Khalifa,Ulf Göransson,Lars Bohlin,Anna-Karin Borg-Karlson,Robert Verpoorte +7 more
TL;DR: The chemistry, biosynthesis, natural sources, dietary intake, and pharmacokinetic properties of hydroxycinnamic acids are discussed.
Journal ArticleDOI
Review: Biocatalytic transformations of ferulic acid: an abundant aromatic natural product
TL;DR: In this review, the fascinating array of microbial and enzymatic transformations of ferulic acid is examined, including cinnamoyl side-chain cleavage; nonoxidative decarboxylation; mechanistic details of styrene formation; and reduction reactions.
References
More filters
Journal ArticleDOI
Urinary metabolites of caffeic and chlorogenic acids.
Journal ArticleDOI
The biohydrogenation of alpha-linolenic acid and oleic acid by rumen micro-organisms.
P. F. Wilde,R. M. C. Dawson +1 more
TL;DR: A tentative scheme for the biohydrogenation route to stearic acid is presented and Butyrivibrio fibrisolvens slowly converted linoleic acid into octadecenoic acid.
Journal ArticleDOI
Metabolic fate of hesperidin, eriodictyol, homoeriodictyol, and diosmin
TL;DR: Three metabolites appearing in the urine of animals after the ingestion of the flavonol quercetin having been identified, the interests were next centered on similar studies of several citrus flavonoids, to find evidence, if any, that these compounds are absorbed from the gastrointestinal tract after oral ingestion.
Journal ArticleDOI
Decarboxylation and demethylation of some phenolic benzoic acid derivatives by rat caecal contents.
TL;DR: Rat caecal contents decarboxylate phenolic benzoic acid derivatives when a free hydroxyl group is in the para position but the presence of substituents adjacent to this group or the carboxyl group reduce or abolish the reaction.
Journal ArticleDOI
Enzyme reactions with phenolic compounds: formation of hydroxystyrenes through the decarboxylation of 4-hydroxycinnamic acids by Aerobacter.
TL;DR: A constitutive nonoxidative decarboxylase from Aerobackr species is described whose substrates are cinnamic acids bearing a 4-hydroxy group, and a cell-free extract of the enzyme showed similarity of sub- strate specificity and pH optimum to the cell-bound enzyme.
Related Papers (5)
Caffeic Acid Metabolism by Bacteria of the Human Gastrointestinal Tract
Mark A. Peppercorn,Peter Goldman +1 more