Journal ArticleDOI
Microfluidics technology for manipulation and analysis of biological cells
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TLDR
This article provides an in-depth review on the applications of microfluidic devices for cell-based assays in recent years, including micro cytometer, micro fluidic chemical cytometry, biochemical sensing chip, and whole cell sensing chip.About:
This article is published in Analytica Chimica Acta.The article was published on 2006-02-23. It has received 540 citations till now. The article focuses on the topics: Biochip & Lab-on-a-chip.read more
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Microfluidic applications of magnetic particles for biological analysis and catalysis.
TL;DR: Keywords: Spin-Valve Sensors ; Cell Tracking Velocimetry ; On-A-Chip ; Polymerase-Chain-Reaction ; Total Analysis Systems ; Iron-Oxide Nanoparticles ; Field-Flow Fractionation ; Cross-Coupling Reactions ; Circulating Tumor-Cells ; Mode Magnetophoretic Microseparator Reference LMIS2-ARTICLE-2010-004
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Fundamentals of microfluidic cell culture in controlled microenvironments
TL;DR: This tutorial review integrates fundamental principles from cell biology and local microenvironments with cell culture techniques and concepts in microfluidics to synthesize fundamental concepts that would further improve the efficiency of biological research at the microscale.
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A practical guide to microfluidic perfusion culture of adherent mammalian cells
TL;DR: The integrative and systematic treatment of the microfluidic system design and fabrication, cell culture, and micro-assays provides novices with an effective starting point to build and operate a robust microfludic perfusion culture system for various applications.
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Effects of dispensing pressure and nozzle diameter on cell survival from solid freeform fabrication-based direct cell writing.
Robert C. Chang,Jae Nam,Wei Sun +2 more
TL;DR: The experimental results revealed a process-induced mechanical damage to cell membrane integrity, causing a quantifiable loss in cell viability due to incremental increases and decreases in the studied process parameters of dispensing pressure and nozzle size, respectively.
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Analysis of single mammalian cells on-chip
TL;DR: This discussion seeks to summarize the state of the art for conventional technologies in use by biologists for the analysis of single, mammalian cells, and then compare LOC devices engineered for these same single-cell studies.
References
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Journal ArticleDOI
Micro Total Analysis Systems. 1. Introduction, Theory, and Technology
TL;DR: In this article, the authors present a review of the book.http://www.reviewreviews.com/reviews/book-reviews-of-the-book
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Microfluidic devices fabricated in Poly(dimethylsiloxane) for biological studies
TL;DR: A review of microfluidic systems in poly(dimethylsiloxane) (PDMS) for biological studies is presented in this paper, which highlights the advantages of miniaturization for biological analysis, such as efficiency of the device and special insights into cell biology.
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Micro total analysis systems. 2. Analytical standard operations and applications.
TL;DR: This second part of the review of microfluidic system preparation will cover a number of standard operations as well as some biological applications of micro total analysis systems.
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Continuous Particle Separation Through Deterministic Lateral Displacement
TL;DR: A microfluidic particle-separation device that makes use of the asymmetric bifurcation of laminar flow around obstacles, which was better than the time and resolution of conventional flow techniques.
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Massively parallel manipulation of single cells and microparticles using optical images.
TL;DR: An optical image-driven dielectrophoresis technique that permits high-resolution patterning of electric fields on a photoconductive surface for manipulating single particles and requires 100,000 times less optical intensity than optical tweezers is presented.