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Molecular biomimetics: nanotechnology through biology

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TLDR
This review discusses combinatorial biological protocols, that is, bacterial cell surface and phage-display technologies, in the selection of short sequences that have affinity to (noble) metals, semiconducting oxides and other technological compounds.
Abstract
Proteins, through their unique and specific interactions with other macromolecules and inorganics, control structures and functions of all biological hard and soft tissues in organisms. Molecular biomimetics is an emerging field in which hybrid technologies are developed by using the tools of molecular biology and nanotechnology. Taking lessons from biology, polypeptides can now be genetically engineered to specifically bind to selected inorganic compounds for applications in nano- and biotechnology. This review discusses combinatorial biological protocols, that is, bacterial cell surface and phage-display technologies, in the selection of short sequences that have affinity to (noble) metals, semiconducting oxides and other technological compounds. These genetically engineered proteins for inorganics (GEPIs) can be used in the assembly of functional nanostructures. Based on the three fundamental principles of molecular recognition, self-assembly and DNA manipulation, we highlight successful uses of GEPI in nanotechnology.

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Journal ArticleDOI

Biofunctionalization of Nano Channels by Direct In-Pore Solid-Phase Peptide Synthesis.

TL;DR: A simple and efficient peptide immobilization strategy was developed, which uses a well-ordered porous silica material as a support and commercially available Fmoc-amino acids, similar to the known solid-phase peptide synthesis, which is suitable for the selective synthesis of pores with tunable surface-peptide functionalization.
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Controlling the structure of proteins at surfaces.

TL;DR: The derived molecular energy landscapes highlight the role of single silk protein structure for the macroscopic toughness of spider silk.
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Adsorption Configuration for Cysteine on Ge(100): Coverage-Dependent Surface Reorientation

TL;DR: In this paper, the adsorption structure and surface reorientation of cysteine molecules on a Ge(100) surface were studied using high-resolution core-level photoemission spectroscopy and low-energy electron diffraction (LEED) to track the variation in the adaption structure as a function of coverage.
Journal ArticleDOI

Die Bildung von Nanopartikeln und Nanostrukturen – CaCO3, Zement und Polymere aus Sicht der Industrie

TL;DR: In this paper, the authors discuss the role of Polymeren in der Nukleation, Templatierung, Stabilisierung and/or Verhinderung of Nanopartikeln.
Journal ArticleDOI

Modulating semiconductor surface electronic properties by inorganic peptide-binders sequence design.

TL;DR: These studies reveal that despite the use of short protein oligomers and aiming at a non-natural-electronic task, the well-known relations between the proteins' structure and function is preserved.
References
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Journal ArticleDOI

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TL;DR: In this paper, a preliminary survey with the electron microscope of various preparations of colloidal gold, a study was made of the process of nucleation and growth in gold colloids, and it was shown that nucleating agents may be identified with reducing agents which form a mixed polymer with chlorauric ion before the reduction to the nucleus takes place.
Journal ArticleDOI

Shape-Controlled Synthesis of Gold and Silver Nanoparticles

TL;DR: Monodisperse samples of silver nanocubes were synthesized in large quantities by reducing silver nitrate with ethylene glycol in the presence of poly(vinyl pyrrolidone) (PVP), characterized by a slightly truncated shape bounded by {100, {110}, and {111} facets.
Journal ArticleDOI

Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface

TL;DR: Foreign DNA fragments can be inserted into filamentous phage gene III to create a fusion protein with the foreign sequence in the middle that is incorporated into the virion, which retains infectivity and displays the foreign amino acids in immunologically accessible form.
PatentDOI

Self-assembly and mineralization of peptide-amphiphile nanofibers

TL;DR: In this paper, pH-induced self-assembly of a peptide-amphiphile was used to make a nanostructured fibrous scaffold reminiscent of extracellular matrix.
Journal ArticleDOI

Molecular self-assembly and nanochemistry: a chemical strategy for the synthesis of nanostructures.

TL;DR: The ability to prepare structures in the upper part of this range of sizes would open a route to structures comparable in size (and perhaps complementary in function) to those that can be prepared by microlithography and other techniques of microfabrication.
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