Near-infrared fluorescence probe with a large Stokes shift for selectively imaging of hydrogen peroxide in living cells and in vivo
TLDR
In this article, the authors designed and synthesized a large stokes shift and near-infrared (NIR) probe DCM-HNU for visualization of H2O2 in both living HeLa cells and zebra fish.About:
This article is published in Dyes and Pigments.The article was published on 2022-01-01 and is currently open access. It has received 8 citations till now. The article focuses on the topics: Stokes shift & Fluorescence.read more
Citations
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A highly selective probe for ratiometric imaging peroxynitrite in living cells and in vivo.
TL;DR: In this article , a ratiometric fluorescent probe JQ-2 was constructed and displayed for the detection of ONOO- with high selectivity over a panel of biological analytes.
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A novel mitochondria-targeted triphenylamine-based fluorescent chemo-sensors for fast detection of H2O2 in living cells and its imaging application
TL;DR: In this paper , a novel reactive H2O2 fluorescent probe TPAQ-H2O 2 based on triphenylamine derivatives was prepared to detect H 2O2 in vivo and in vitro, which exhibited an intense Stokes shift (239 nm), exhibited high selectivity (LOD= 2.5 µmol) and quick response to H 2 O2 in DMSO/PBS buffer (4/6, v/v) solution in the presence of other competing substances.
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A novel pyrazoline-based fluorescence probe armed by pyrene and naphthol system for the selective detection of Cu2+ and its biological application
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Reasonable construction of a unique near-infrared fluorescent probe with improved performance for imaging β-galactosidase in living cells and in vivo
TL;DR: Wang et al. as discussed by the authors designed a NIR fluorescent probe (DCM-CHO-βgal ) with improved near-infrared fluorescence emission and detection performance for the quantification and visualization of β-gal, employing structurally modified dicyanobenzopyran derivative ( DCM -CHO-OH ) as fluorophore.
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2-(2-(Dimethylamino)vinyl)-4H-pyran-4-ones as Novel and Convenient Building-Blocks for the Synthesis of Conjugated 4-Pyrone Derivatives
Dmitrii L. Obydennov,Diana I. Nigamatova,Alexander S. Shirinkin,Oleg E. Melnikov,V. V. Fedin,Sergey A. Usachev,Alena E. Simbirtseva,Mikhail Yu. Kornev,Vyacheslav Ya. Sosnovskikh +8 more
TL;DR: A straightforward approach for the construction of conjugated pyrans based on enamination of 2-methyl-4-pyrones with DMF-DMA was developed in this article .
References
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Guidelines for data acquisition and data quality evaluation in environmental chemistry
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Fluorescent and luminescent probes for measurement of oxidative and nitrosative species in cells and tissues: progress, pitfalls, and prospects.
TL;DR: Progress in the development of probes for "reactive oxygen and nitrogen" species, emphasizing the caution needed in their use is reviewed, with a focus on probes based on reduced dyes.
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Methods for detection and measurement of hydrogen peroxide inside and outside of cells
TL;DR: Deprotection reaction-based probes (PG1 and PC1) that fluoresce on H2O2-specific removal of a boronate group rather than on nonspecific oxidation have recently been developed for selective measurement of H 2O2 in cells, and a new class of organelle-targetable fluorescent probes has been devised by joining PG1 to a substrate of SNAP-tag.
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Reaction-Based Fluorescent Probes for the Detection and Imaging of Reactive Oxygen, Nitrogen, and Sulfur Species.
TL;DR: The aim with this Account is to introduce the fluorescent probes that have developed for in vitro and in vivo measurement of ROS, RNS, and RSS, and the use of an ESIPT-based probe for the simultaneous sensing of fibrous proteins/peptides AND environmental ROS/RNS.
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Dihydrorhodamine 123: a fluorescent probe for superoxide generation?
TL;DR: DHR oxidation reports only the presence of H2O2 and intracellular peroxidases, and not the generation of O2-. by any one cell, which means that in a mixed population DHR failed to distinguish between O2-.-producing and non-producing HL60 cells it is not a suitable probe for single-cell observations.