Neural activity associated with self, other, and object-based counterfactual thinking
TLDR
The results suggest that different brain mechanisms are involved in the simulation of personal and impersonal counterfactual thoughts, and that the extent to which regions associated with autobiographical memory are recruited during the Simulation of Counterfactuals involving others depends on the perceived similarity and familiarity with the simulated individuals.About:
This article is published in NeuroImage.The article was published on 2015-04-01 and is currently open access. It has received 51 citations till now. The article focuses on the topics: Counterfactual thinking & Counterfactual conditional.read more
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Autobiographical memory decline in Alzheimer's disease, a theoretical and clinical overview
TL;DR: It is proposed that autobiographical recall in AD is mainly characterized by loss of associated episodic information, which leads to de-contextualization of autobiographical memories and a shift from reliving past events to a general sense of familiarity.
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Computations Underlying Social Hierarchy Learning: Distinct Neural Mechanisms for Updating and Representing Self-Relevant Information.
TL;DR: It is shown that a Bayesian inference scheme, which tracks the power of individuals, better captures behavioral and neural data compared with a reinforcement learning model inspired by rating systems used in games such as chess.
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Morality constrains the default representation of what is possible
Jonathan Phillips,Fiery Cushman +1 more
TL;DR: It is demonstrated that human adults often default to treating immoral and irrational events as impossible, and a case study of high-level cognitive judgments relying on default implicit representations of possibility rather than explicit deliberation is provided.
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Anosognosia in Alzheimer disease: Disconnection between memory and self-related brain networks
Audrey Perrotin,Béatrice Desgranges,Brigitte Landeau,Florence Mézenge,Renaud La Joie,Stéphanie Egret,Alice Pélerin,Vincent de la Sayette,Francis Eustache,Gaël Chételat +9 more
TL;DR: This study aims at improving the understanding of the neural mechanisms underlying anosognosia of memory deficits in AD by combining measures of regional brain metabolism and intrinsic connectivity and fMRI.
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Apolipoprotein E (APOE) ε4 and episodic memory decline in Alzheimer’s disease: A review
Mohamad El Haj,Pascal Antoine,Philippe Amouyel,Jean-Charles Lambert,Florence Pasquier,Dimitrios Kapogiannis +5 more
TL;DR: A systematic search for studies assessing episodic memory in AD patients who were genotyped for APOE ε4 and identified fourteen papers, which identified several shortcoming and limitations, such as small sample sizes, non-representative populations, lack of comparison of early-ONSet vs. late-onset disease, and lack of compare among different genotypes that include APOEε4.
References
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The Brain's Default Network Anatomy, Function, and Relevance to Disease
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.
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