Journal ArticleDOI
Neurogenic Detrusor Overactivity in Patients With Spinal Cord Injury: Evaluation and Management
Arun Sahai,Eduardo Cortes,Jai Seth,Muhammad Shamim Khan,Jalesh N. Panicker,C. Kelleher,Thomas M. Kessler,Clare J. Fowler,Prokar Dasgupta +8 more
TLDR
This article reviews the assessment and management of neurogenic detrusor overactivity, with a particular focus on articles from the recent literature.Abstract:
Lower urinary tract dysfunction can have a significant impact on patients with spinal cord injury. Over the years, many treatment options have become available. This article reviews the assessment and management of neurogenic detrusor overactivity, with a particular focus on articles from the recent literature. Recent guidelines on the subject will be discussed. Management options include antimuscarinics and bladder emptying measures, botulinum toxin A, and neuromodulation in refractory cases and surgery for intractable cases. Recent and relevant publications in these areas will be summarized and discussed.read more
Citations
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Journal ArticleDOI
Biomarkers in Spinal Cord Injury: Prognostic Insights and Future Potentials.
Ahmed Albayar,Abigail Roche,Przemyslaw Swiatkowski,Sarah Antar,Nouran Ouda,Eman Emara,Douglas H. Smith,Ali K. Ozturk,Basem I. Awad +8 more
TL;DR: An extensive literature review was performed covering literature, published in English, until February 2018 using the Medline/PubMed database, and observed two methods that may lead to the appearance of biomarkers for SCI.
Journal ArticleDOI
The possible role of percutaneous tibial nerve stimulation using adhesive skin surface electrodes in patients with neurogenic detrusor overactivity secondary to spinal cord injury
TL;DR: PTNS therapy with adhesive skin surface electrodes is an effective method to treat NDO secondary to SCI and is not only no difference comparing to SS therapy but also noninvasive and easily managed by patients.
Journal ArticleDOI
The Role of Brain-Derived Neurotrophic Factor (BDNF) in the Development of Neurogenic Detrusor Overactivity (NDO)
Bárbara Frias,João Paulo Fernandes Santos,Marlene M. Morgado,Mónica Mendes Sousa,Susannah Gray,Karen D. McCloskey,Shelley J Allen,Francisco Cruz,Célia D. Cruz +8 more
TL;DR: Chronic BDNF administration inhibited the emergence of NDO, together with reduction of axonal growth, suggesting that BDNF may have a crucial role in bladder function after SCI via inhibition of neuronal sprouting.
Patent
Topical neurological stimulation
TL;DR: A topical nerve stimulator patch and system comprising a dermal patch, an electrical signal generator associated with the patch, a signal receiver to activate the generator, and a power source for the generator are described in this paper.
Journal ArticleDOI
Pathophysiology of the underactive bladder.
Naoki Aizawa,Yasuhiko Igawa +1 more
TL;DR: Relationships between individual contributing factors and the pathophysiology of UAB are described based on previous reports, but many pathophysiological uncertainties still remain, which require more investigations using appropriate animal models.
References
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Journal ArticleDOI
The neural control of micturition
TL;DR: The neural control of micturition is reviewed and how disruption of this control leads to abnormal storage and release of urine.
Journal ArticleDOI
Prognostic Value of Urodynamic Testing in Myelodysplastic Patients
Edward J. McGuire,Edward J. McGuire,Jeffrey R. Woodside,Jeffrey R. Woodside,Thomas A. Borden,Thomas A. Borden,Robert M. Weiss,Robert M. Weiss +7 more
TL;DR: Assessment of urethral function showed 36 patients (86 per cent) with an open vesical outlet and nonfunctional proximal urethra and 7 of 42 patients had reflex detrusor activity: 4 with coordinated micturition and 3 withdetrusor-sphincter dyssynergia.
Journal ArticleDOI
The Effects of Antimuscarinic Treatments in Overactive Bladder: An Update of a Systematic Review and Meta-Analysis
Christopher R. Chapple,Vik Khullar,Zahava Gabriel,Dominic Muston,Caty Ebel Bitoun,David Weinstein +5 more
TL;DR: Antimuscarinics are efficacious, safe, and well-tolerated treatments that improve HRQL and should be considered in making treatment choices.
Journal ArticleDOI
Botulinum toxin type A is a safe and effective treatment for neurogenic urinary incontinence: results of a single treatment, randomized, placebo controlled 6-month study.
Brigitte Schurch,Marianne de Sèze,Pierre Denys,Emmanuel Chartier-Kastler,François Haab,Karel Everaert,Pierre Plante,Brigitte Perrouin-Verbe,Catherine Kumar,S Fraczek,Mitchell F. Brin +10 more
TL;DR: Intramuscular injections of BTX-A into the detrusor can provide rapid, well tolerated, clinically significant decreases in the signs and symptoms of urinary incontinence caused by neurogenicdetrusor overactivity during a 24-week study period.
Journal ArticleDOI
EAU Guidelines on Neurogenic Lower Urinary Tract Dysfunction
Manfred Stöhrer,Bertil F.M. Blok,David Castro-Diaz,E. Chartier-Kastler,Giulio Del Popolo,G. Kramer,Jürgen Pannek,Piotr Radziszewski,Jean-Jacques Wyndaele +8 more
TL;DR: The diagnosis and treatment of NLUTD, which is a highly specialised and complex field involving both urology and medicine, requires up-to-date expert advice to be readily available and the current guidelines are designed to fulfil this need.
Related Papers (5)
The Evaluation and Management of Refractory Neurogenic Overactive Bladder
Raj Kurpad,Michael J. Kennelly +1 more