Journal ArticleDOI
Normalization of Lactulose Breath Testing Correlates With Symptom Improvement in Irritable Bowel Syndrome: A Double-Blind, Randomized, Placebo-Controlled Study
TLDR
Normalization of LBT with neomycin leads to a significant reduction in IBS symptoms, and the type of gas seen on LBT is also associated with IBS subgroup.About:
This article is published in The American Journal of Gastroenterology.The article was published on 2003-02-01. It has received 648 citations till now. The article focuses on the topics: Breath test & Irritable bowel syndrome.read more
Citations
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Journal ArticleDOI
Functional Bowel Disorders
George F. Longstreth,W. Grant Thompson,William D. Chey,Lesley A. Houghton,Fermín Mearin,Robin C. Spiller +5 more
TL;DR: Employing a consensus approach, the working team critically considered the available evidence and multinational expert criticism, revised the Rome II diagnostic criteria for the functional bowel disorders, and updated diagnosis and treatment recommendations.
Journal ArticleDOI
Lactobacillus and bifidobacterium in irritable bowel syndrome: Symptom responses and relationship to cytokine profiles
Liam O'Mahony,Jane McCarthy,Peter Kelly,George J Hurley,Fangyi Luo,Ker-Sang Chen,Gerald C. O'Sullivan,Barry Kiely,J. Kevin Collins,Fergus Shanahan,Eamonn Martin Quigley +10 more
TL;DR: B infantis 35624 alleviates symptoms in IBS; this symptomatic response was associated with normalization of the ratio of an anti-inflammatory to a proinflammatory cytokine, suggesting an immune-modulating role for this organism, in this disorder.
Journal ArticleDOI
Rifaximin Therapy for Patients with Irritable Bowel Syndrome without Constipation
Mark Pimentel,Anthony Lembo,William D. Chey,Salam Zakko,Yehuda Ringel,Jing Yu,Shadreck M. Mareya,Audrey L. Shaw,Enoch Bortey,William P. Forbes +9 more
TL;DR: Among patients who had IBS without constipation, treatment with rifaximin for 2 weeks provided significant relief of IBS symptoms, bloating, abdominal pain, and loose or watery stools.
Journal ArticleDOI
Guidelines on the irritable bowel syndrome: mechanisms and practical management
Robin C. Spiller,Robin C. Spiller,Qasim Aziz,Francis Creed,Anton Emmanuel,Lesley A. Houghton,Pali Hungin,Roger Jones,D Kumar,Greg Rubin,Nigel Trudgill,Peter J. Whorwell +11 more
TL;DR: Better ways of identifying which patients will respond to specific treatments are urgently needed for the assessment and management of adult patients with irritable bowel syndrome.
Journal ArticleDOI
Intestinal microbiota in functional bowel disorders: a Rome foundation report
Magnus Simren,Giovanni Barbara,Harry J. Flint,Brennan Spiegel,Robin C. Spiller,Stephen J. Vanner,Elena F. Verdu,Peter J. Whorwell,Erwin G. Zoetendal +8 more
TL;DR: A critical review of current hypotheses regarding the pathogenetic involvement of microbiota in FGID is provided and the results of microbiota-directed interventions are evaluated and clinical guidance on modulation of gut microbiota in IBS is provided.
References
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Journal ArticleDOI
Functional bowel disorders and functional abdominal pain.
TL;DR: A committee consensus approach, including criticism from multinational expert reviewers, was used to revise the diagnostic criteria and update diagnosis and treatment recommendations, based on research results.
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Eradication of small intestinal bacterial overgrowth reduces symptoms of irritable bowel syndrome
TL;DR: An improvement in irritable bowel syndrome symptoms with diarrhea and abdominal pain being statistically significant after Bonferroni correction is revealed.
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Bowel patterns among subjects not seeking health care. Use of a questionnaire to identify a population with bowel dysfunction.
TL;DR: In this article, the authors devised a brief selfadministered questionnaire which, when used among a group of 789 students and hospital employees, disclosed that 94.2% had stool frequencies between three per day and three per week, and that 17.1% had bowel dysfunction.
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Functional Bowel Disorders in Apparently Healthy People
TL;DR: Four clinically distinct functional bowel syndromes existed in almost one-third of the subjects studied, and constipation seemed to increase with age.
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Prevalence of gastrointestinal symptoms six months after bacterial gastroenteritis and risk factors for development of the irritable bowel syndrome: postal survey of patients.
TL;DR: Persistence of bowel symptoms commonly occurs after bacterial gastroenteritis and is responsible for considerable morbidity and health care costs.