On the relationship between the "default mode network" and the "social brain".
Rogier B. Mars,Rogier B. Mars,Rogier B. Mars,Franz-Xaver Neubert,MaryAnn P. Noonan,MaryAnn P. Noonan,Jerome Sallet,Jerome Sallet,Ivan Toni,Matthew F. S. Rushworth,Matthew F. S. Rushworth +10 more
TLDR
This claim that social cognition, particularly higher-order tasks such as attributing mental states to others, has been suggested to activate a network of areas at least partly overlapping with the DMN is explored, drawing on evidence from meta-analyses of functional MRI data and recent studies investigating the structural and functional connectivity of the social brain.Abstract:
The default mode network (DMN) of the brain consists of areas that are typically more active during rest than during active task performance. Recently however, this network has been shown to be activated by certain types of tasks. Social cognition, particularly higher-order tasks such as attributing mental states to others, has been suggested to activate a network of areas at least partly overlapping with the DMN. Here, we explore this claim, drawing on evidence from meta-analyses of functional MRI data and recent studies investigating the structural and functional connectivity of the social brain. In addition, we discuss recent evidence for the existence of a DMN in non-human primates. We conclude by discussing some of the implications of these observations.read more
Citations
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The social brain in psychiatric and neurological disorders.
Daniel P. Kennedy,Ralph Adolphs +1 more
TL;DR: It is suggested that the social brain, and its dysfunction and recovery, must be understood not in terms of specific structures, but rather in Terms of their interaction in large-scale networks.
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Informatic parcellation of the network involved in the computation of subjective value.
John A. Clithero,Antonio Rangel +1 more
TL;DR: A meta-analysis of a large set of functional magnetic resonance imaging studies of value computation to address several key questions, demonstrating the centrality of ventromedial prefrontal cortex, ventral striatum and posterior cingulate cortex in the computation of value across tasks, reward modalities and stages of the decision-making process.
Journal ArticleDOI
Cognitive deficits and functional outcomes in major depressive disorder: determinants, substrates, and treatment interventions.
Roger S. McIntyre,Danielle S. Cha,Joanna K. Soczynska,Hanna O. Woldeyohannes,Laura Ashley Gallaugher,Paul Kudlow,Mohammad Alsuwaidan,Anusha Baskaran,Anusha Baskaran +8 more
TL;DR: Few reports have aimed to describe the mediational effect of cognitive deficits on functional outcomes in major depressive disorder, and relatively few interventions are demonstrated to mitigate cognitive deficits in MDD.
Journal ArticleDOI
The brain’s default network: updated anatomy, physiology and evolving insights
TL;DR: Progress in understanding the organization and function of networks embedded within association regions is described, with findings from humans, monkeys and rodents indicating that multiple subnetworks make up the default network.
Journal ArticleDOI
Sex Differences in the Adult Human Brain: Evidence from 5216 UK Biobank Participants
Stuart J. Ritchie,Simon R. Cox,Xueyi Shen,Michael V. Lombardo,Michael V. Lombardo,Lianne M. Reus,Clara Alloza,Mathew A. Harris,Helen L Alderson,Stuart Hunter,Emma Neilson,David C. Liewald,Bonnie Auyeung,Heather C. Whalley,Stephen M. Lawrie,Catharine R. Gale,Catharine R. Gale,Mark E. Bastin,Andrew M. McIntosh,Ian J. Deary +19 more
TL;DR: This large-scale study provides a foundation for attempts to understand the causes and consequences of sex differences in adult brain structure and function.
References
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Journal ArticleDOI
A default mode of brain function.
Marcus E. Raichle,Ann Mary MacLeod,Abraham Z. Snyder,William J. Powers,Debra A. Gusnard,Gordon L. Shulman +5 more
TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
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The Brain's Default Network Anatomy, Function, and Relevance to Disease
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.
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Functional connectivity in the resting brain: A network analysis of the default mode hypothesis
TL;DR: This study constitutes, to the knowledge, the first resting-state connectivity analysis of the default mode and provides the most compelling evidence to date for the existence of a cohesive default mode network.
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Correspondence of the brain's functional architecture during activation and rest.
Stephen M. Smith,Peter T. Fox,Karla L. Miller,David C. Glahn,P. Mickle Fox,Clare E. Mackay,Nicola Filippini,Kate E. Watkins,Roberto Toro,Angela R. Laird,Christian F. Beckmann,Christian F. Beckmann +11 more
TL;DR: It is concluded that the full repertoire of functional networks utilized by the brain in action is continuously and dynamically “active” even when at “rest.”
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Mapping the Structural Core of Human Cerebral Cortex
Patric Hagmann,Leila Cammoun,Xavier Gigandet,Reto Meuli,Christopher J. Honey,Van J. Wedeen,Olaf Sporns +6 more
TL;DR: The spatial and topological centrality of the core within cortex suggests an important role in functional integration and a substantial correspondence between structural connectivity and resting-state functional connectivity measured in the same participants.