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Ian J. Deary
Researcher at University of Edinburgh
Publications - 62
Citations - 5035
Ian J. Deary is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Genome-wide association study & Cognition. The author has an hindex of 29, co-authored 62 publications receiving 3544 citations.
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Journal ArticleDOI
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
Jeanne E. Savage,Philip R. Jansen,Philip R. Jansen,Sven Stringer,Kyoko Watanabe,Julien Bryois,Christiaan de Leeuw,Mats Nagel,Swapnil Awasthi,Peter B. Barr,Jonathan R. I. Coleman,Katrina L. Grasby,Anke R. Hammerschlag,Jakob Kaminski,Robert Karlsson,Eva Krapohl,Max Lam,Marianne Nygaard,Chandra A. Reynolds,Joey W. Trampush,Hannah Young,Delilah Zabaneh,Sara Hägg,Narelle K. Hansell,Ida K. Karlsson,Sten Linnarsson,Grant W. Montgomery,Grant W. Montgomery,Ana B. Muñoz-Manchado,Erin Burke Quinlan,Gunter Schumann,Nathan G. Skene,Nathan G. Skene,Bradley T. Webb,Tonya White,Dan E. Arking,Dimitrios Avramopoulos,Robert M. Bilder,Panos Bitsios,Katherine E. Burdick,Katherine E. Burdick,Katherine E. Burdick,Tyrone D. Cannon,Ornit Chiba-Falek,Andrea Christoforou,Elizabeth T. Cirulli,Eliza Congdon,Aiden Corvin,Gail Davies,Ian J. Deary,Pamela DeRosse,Pamela DeRosse,Dwight Dickinson,Srdjan Djurovic,Srdjan Djurovic,Gary Donohoe,Emily Drabant Conley,Johan G. Eriksson,Thomas Espeseth,Nelson A. Freimer,Stella G. Giakoumaki,Ina Giegling,Michael Gill,David C. Glahn,Ahmad R. Hariri,Alex Hatzimanolis,Alex Hatzimanolis,Matthew C. Keller,Emma Knowles,Deborah C. Koltai,Bettina Konte,Jari Lahti,Stephanie Le Hellard,Todd Lencz,Todd Lencz,David C. Liewald,Edythe D. London,Astri J. Lundervold,Anil K. Malhotra,Anil K. Malhotra,Ingrid Melle,Ingrid Melle,Derek W. Morris,Anna C. Need,William Ollier,Aarno Palotie,Aarno Palotie,Aarno Palotie,Antony Payton,Neil Pendleton,Russell A. Poldrack,Katri Räikkönen,Ivar Reinvang,Panos Roussos,Panos Roussos,Dan Rujescu,Fred W. Sabb,Matthew A. Scult,Olav B. Smeland,Nikolaos Smyrnis,Nikolaos Smyrnis,John M. Starr,Vidar M. Steen,Nikos C. Stefanis,Nikos C. Stefanis,Richard E. Straub,Kjetil Sundet,Henning Tiemeier,Aristotle N. Voineskos,Daniel R. Weinberger,Elisabeth Widen,Jin Yu,Gonçalo R. Abecasis,Ole A. Andreassen,Gerome Breen,Lene Christiansen,Birgit Debrabant,Danielle M. Dick,Andreas Heinz,Jens Hjerling-Leffler,M. Arfan Ikram,Kenneth S. Kendler,Nicholas G. Martin,Sarah E. Medland,Nancy L. Pedersen,Robert Plomin,Tinca J. C. Polderman,Stephan Ripke,Stephan Ripke,Stephan Ripke,Sophie van der Sluis,Patrick Sullivan,Patrick Sullivan,Scott I. Vrieze,Margaret J. Wright,Danielle Posthuma +135 more
TL;DR: A large-scale genetic association study of intelligence identifies 190 new loci and implicates 939 new genes related to neurogenesis, neuron differentiation and synaptic structure, a major step forward in understanding the neurobiology of cognitive function as well as genetically related neurological and psychiatric disorders.
Journal ArticleDOI
Sex Differences in the Adult Human Brain: Evidence from 5216 UK Biobank Participants
Stuart J. Ritchie,Simon R. Cox,Xueyi Shen,Michael V. Lombardo,Michael V. Lombardo,Lianne M. Reus,Clara Alloza,Mathew A. Harris,Helen L Alderson,Stuart Hunter,Emma Neilson,David C. Liewald,Bonnie Auyeung,Heather C. Whalley,Stephen M. Lawrie,Catharine R. Gale,Catharine R. Gale,Mark E. Bastin,Andrew M. McIntosh,Ian J. Deary +19 more
TL;DR: This large-scale study provides a foundation for attempts to understand the causes and consequences of sex differences in adult brain structure and function.
Journal ArticleDOI
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Gail Davies,Max Lam,Sarah E. Harris,Joey W. Trampush,Michelle Luciano,W. David Hill,Saskia P. Hagenaars,Saskia P. Hagenaars,Stuart J. Ritchie,Riccardo E. Marioni,Chloe Fawns-Ritchie,David C. Liewald,Judith A. Okely,Ari Ahola-Olli,Catriona L. K. Barnes,Lars Bertram,Joshua C. Bis,Katherine E. Burdick,Katherine E. Burdick,Katherine E. Burdick,Andrea Christoforou,Pamela DeRosse,Srdjan Djurovic,Srdjan Djurovic,Thomas Espeseth,Stella G. Giakoumaki,Sudheer Giddaluru,Daniel E. Gustavson,Caroline Hayward,Edith Hofer,M. Arfan Ikram,Robert Karlsson,Emma Knowles,Jari Lahti,Markus Leber,Shuo Li,Karen A. Mather,Ingrid Melle,Ingrid Melle,Derek W. Morris,Christopher Oldmeadow,Teemu Palviainen,Antony Payton,Raha Pazoki,Katja Petrovic,Chandra A. Reynolds,Muralidharan Sargurupremraj,Markus Scholz,Jennifer A. Smith,Albert V. Smith,Natalie Terzikhan,Natalie Terzikhan,Anbupalam Thalamuthu,Stella Trompet,Sven J. van der Lee,Erin B. Ware,Beverly Gwen Windham,Margaret J. Wright,Jingyun Yang,Jin Yu,David Ames,David Ames,Najaf Amin,Philippe Amouyel,Ole A. Andreassen,Nicola J. Armstrong,Amelia A. Assareh,John Attia,Deborah K. Attix,Dimitrios Avramopoulos,David A. Bennett,Anne C. Böhmer,Patricia A. Boyle,Henry Brodaty,Harry Campbell,Tyrone D. Cannon,Elizabeth T. Cirulli,Eliza Congdon,Emily Drabant Conley,Janie Corley,Simon R. Cox,Anders M. Dale,Abbas Dehghan,Danielle M. Dick,Dwight Dickinson,Johan G. Eriksson,Johan G. Eriksson,Evangelos Evangelou,Evangelos Evangelou,Jessica D. Faul,Ian Ford,Nelson A. Freimer,He Gao,Ina Giegling,Nathan A. Gillespie,Scott D. Gordon,R. F. Gottesman,Michael Griswold,Vilmundur Gudnason,Tamara B. Harris,Annette M. Hartmann,Alex Hatzimanolis,Alex Hatzimanolis,Gerardo Heiss,Elizabeth G. Holliday,Peter K. Joshi,Mika Kähönen,Sharon L.R. Kardia,Ida K. Karlsson,Luca Kleineidam,Luca Kleineidam,Luca Kleineidam,David S. Knopman,Nicole A. Kochan,Bettina Konte,John B.J. Kwok,John B.J. Kwok,Stephanie Le Hellard,Teresa Lee,Terho Lehtimäki,Shu-Chen Li,Shu-Chen Li,Tian Liu,Marisa Koini,Edythe D. London,Will Longstreth,Oscar L. Lopez,Anu Loukola,Tobias Luck,Astri J. Lundervold,Anders Lundquist,Leo-Pekka Lyytikäinen,Nicholas G. Martin,Grant W. Montgomery,Grant W. Montgomery,Alison D. Murray,Alison D. Murray,Anna C. Need,Raymond Noordam,Lars Nyberg,William Ollier,Goran Papenberg,Goran Papenberg,Alison Pattie,Ozren Polasek,Russell A. Poldrack,Bruce M. Psaty,Bruce M. Psaty,Simone Reppermund,Steffi G. Riedel-Heller,Richard J. Rose,Jerome I. Rotter,Panos Roussos,Panos Roussos,Suvi P. Rovio,Yasaman Saba,Fred W. Sabb,Perminder S. Sachdev,Claudia L. Satizabal,Claudia L. Satizabal,Matthias Schmid,Rodney J. Scott,Matthew A. Scult,Jeannette Simino,P. Eline Slagboom,Nikolaos Smyrnis,Nikolaos Smyrnis,Aicha Soumare,Nikos C. Stefanis,Nikos C. Stefanis,David J. Stott,Richard E. Straub,Kjetil Sundet,Adele M. Taylor,Kent D. Taylor,Ioanna Tzoulaki,Ioanna Tzoulaki,Christophe Tzourio,Christophe Tzourio,André G. Uitterlinden,Veronique Vitart,Aristotle N. Voineskos,Jaakko Kaprio,Jaakko Kaprio,Michael Wagner,Michael Wagner,Holger Wagner,Leonie Weinhold,K. Hoyan Wen,Elisabeth Widen,Qiong Yang,Wei Zhao,Hieab H.H. Adams,Dan E. Arking,Robert M. Bilder,Panos Bitsios,Eric Boerwinkle,Eric Boerwinkle,Ornit Chiba-Falek,Aiden Corvin,Philip L. De Jager,Philip L. De Jager,Stéphanie Debette,Stéphanie Debette,Gary Donohoe,Paul Elliott,Annette L. Fitzpatrick,Michael Gill,David C. Glahn,Sara Hägg,Narelle K. Hansell,Ahmad R. Hariri,M. Kamran Ikram,J. Wouter Jukema,Eero Vuoksimaa,Matthew C. Keller,William S. Kremen,Lenore J. Launer,Ulman Lindenberger,Aarno Palotie,Aarno Palotie,Nancy L. Pedersen,Neil Pendleton,David J. Porteous,Katri Räikkönen,Olli T. Raitakari,Alfredo Ramirez,Alfredo Ramirez,Ivar Reinvang,Igor Rudan,Dan Rujescu,Reinhold Schmidt,Helena Schmidt,Peter W. Schofield,Peter R. Schofield,Peter R. Schofield,John M. Starr,Vidar M. Steen,Julian N. Trollor,Steven T. Turner,Cornelia M. van Duijn,Arno Villringer,Arno Villringer,Daniel R. Weinberger,David R. Weir,James F. Wilson,Anil K. Malhotra,Anil K. Malhotra,Andrew M. McIntosh,Catharine R. Gale,Sudha Seshadri,Sudha Seshadri,Sudha Seshadri,Thomas H. Mosley,Jan Bressler,Todd Lencz,Todd Lencz,Ian J. Deary +257 more
TL;DR: In this paper, the authors combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank (total N = 300,486; age 16-102) and find 148 genome-wide significant independent loci associated with general cognitive function.
Journal ArticleDOI
Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
David M. Howard,Mark Adams,Masoud Shirali,Toni-Kim Clarke,Riccardo E. Marioni,Gail Davies,Jonathan R. I. Coleman,Jonathan R. I. Coleman,Clara Alloza,Xueyi Shen,Miruna C. Barbu,Eleanor M. Wigmore,Jude Gibson,Saskia P. Hagenaars,Saskia P. Hagenaars,Cathryn M. Lewis,Cathryn M. Lewis,Joey Ward,Daniel J. Smith,Patrick Sullivan,Patrick Sullivan,Chris Haley,Gerome Breen,Gerome Breen,Ian J. Deary,Andrew M. McIntosh +25 more
TL;DR: It is suggested that broad depression is the most tractable UK Biobank phenotype for discovering genes and gene sets that further the understanding of the biological pathways underlying depression.
Journal ArticleDOI
Ageing and brain white matter structure in 3,513 UK Biobank participants.
Simon R. Cox,Stuart J. Ritchie,Elliot M. Tucker-Drob,David C. Liewald,Saskia P. Hagenaars,Gail Davies,Joanna M. Wardlaw,Catharine R. Gale,Mark E. Bastin,Ian J. Deary +9 more
TL;DR: Results from this unusually large, single-scanner sample provide one of the most extensive characterizations of age associations with major white matter tracts in the human brain, with negative age associations strongest in the thalamic radiation and association fibres.