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Journal ArticleDOI

Online measurement of dissolved oxygen in shake flask to elucidate its role on caffeine degradation by Pseudomonas sp.

TLDR
Higher DO in the medium is required for efficient conversion of caffeine to theobromine which is in agreement that the reaction is oxidative demethylation which will be useful in shaking flask studies and scaling up processes.
Abstract
Caffeine is a plant alkaloid present in the large ratio over other emerging pollutants and it causes serious health effects on overdosage. Microbial degradation of caffeine produces metabolites tha...

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Citations
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Self-directing optimization for enhanced caffeine degradation in synthetic coffee wastewater using induced cells of Pseudomonas sp.: Bioreactor studies

TL;DR: In this paper, a regression model was developed to predict the caffeine degradation rate with oxygen mass transfer coefficient (kLa) and initial biomass concentration, and the optimal conditions of initial biomass and kLa were 0.23g/L and 64.26h−1 respectively.
Journal ArticleDOI

Monitoring of Oxygen, pH, CO 2 , and Biomass in Smart Single‐Use Shake Flasks

TL;DR: In this article , optical sensors are employed in single-use shake flasks to measure oxygen, carbon dioxide, pH, and biomass, and optical sensors can also be used to measure carbon dioxide and carbon dioxide.
Journal ArticleDOI

Optimization by uniform design U8(83) approach for enhanced caffeine degradation in synthetic wastewater in bioreactor

TL;DR: This is the first‐ever bioreactor study showing highest caffeine degradation rate in synthetic coffee wastewater with limited experimental runs.
References
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Journal ArticleDOI

Genetic characterization of caffeine degradation by bacteria and its potential applications.

TL;DR: Various biotechnological applications of these genes responsible for bacterial caffeine degradation, including bio‐decaffeination, remediation of caffeine‐contaminated environments, production of chemical and fuels and development of diagnostic tests have also been demonstrated.
Journal ArticleDOI

Risks of caffeine residues in the environment: Necessity for a targeted ecopharmacovigilance program.

TL;DR: It is proposed that caffeine should be considered as a high-priority environmentally hazardous PhAC pollutant, and it is necessary to implement an ecopharmacovigilance (EPV) program targeting caffeine to minimize its environmental load from a pharmacy perspective.
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Caffeine and paraxanthine in aquatic systems: Global exposure distributions and probabilistic risk assessment.

TL;DR: Caffeine, as well as its main metabolite (paraxanthine), were selected for this study, and it was determined that unacceptable environmental risk could be expected from chronic exposure to caffeine from effluent, surface water, and estuary water.
Journal ArticleDOI

A preliminary study of caffeine degradation by Pseudomonas sp. GSC 1182

TL;DR: Several microorganisms isolated from soil were tested for their ability to utilize caffeine as the sole carbon and nitrogen source and showed decreased level (<10%) of caffeine degradation in the presence of glucose.
Journal ArticleDOI

Caffeine degradation by methanogenesis: Efficiency in anaerobic membrane bioreactor and analysis of kinetic behavior

TL;DR: A reaction equation for the caffeine degradation by methanogenesis based on the stoichiometric relationship between the degraded caffeine and the increased end-products: CH4, NH4+-N and CO2 is proposed and confirmed and provided a new thought to microbial caffeine degradation.