Journal ArticleDOI
Optical properties of biological tissues: a review.
TLDR
A review of reported tissue optical properties summarizes the wavelength-dependent behavior of scattering and absorption in cells and tissues.Abstract:
A review of reported tissue optical properties summarizes the wavelength-dependent behavior of scattering and absorption. Formulae are presented for generating the optical properties of a generic tissue with variable amounts of absorbing chromophores (blood, water, melanin, fat, yellow pigments) and a variable balance between small-scale scatterers and large-scale scatterers in the ultrastructures of cells and tissues.read more
Citations
More filters
Journal ArticleDOI
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
TL;DR: The current status and possible opportunities for ROS generation for cancer therapy are summarized and it is hoped this review will spur pre-clinical research and clinical practice for ROS-mediated tumour treatments.
Journal ArticleDOI
Nanotechnology for Multimodal Synergistic Cancer Therapy
TL;DR: In this review, state-of-the-art studies concerning recent advances in nanotechnology-mediated multimodal synergistic therapy will be systematically discussed, with an emphasis on the construction of multifunctional nanomaterials for realizing bimodal and trimodal synergy therapy.
Journal ArticleDOI
Effect of wavelength and beam width on penetration in light-tissue interaction using computational methods
TL;DR: Penetration depth of ultraviolet, visible light and infrared radiation in biological tissue has not previously been adequately measured and its effect on the energy density (fluence) distribution within tissue and thus the treatment efficacy depends upon the illumination geometry and wavelength.
Journal ArticleDOI
Lifetime-engineered NIR-II nanoparticles unlock multiplexed in vivo imaging.
Yong Fan,Peiyuan Wang,Yiqing Lu,Rui Wang,Lei Zhou,Xianlin Zheng,Xiaomin Li,James A. Piper,Fan Zhang +8 more
TL;DR: Lanthanide-doped NIR-II nanoparticles with engineered luminescence lifetimes are presented with in vivo quantitative imaging using time-domain multiplexing to identify tumour subtypes in living mice and it is demonstrated that robust lifetime coding is independent of tissue penetration depth.
Journal ArticleDOI
Light in diagnosis, therapy and surgery.
TL;DR: The fundamentals of light–matter interactions are revisited, the applications of light in imaging, diagnosis, therapy and surgery are described, their clinical use is overviewed, and the promise of emerging light-based technologies are discussed.
References
More filters
Journal ArticleDOI
Optical Constants of Water in the 200-nm to 200-microm Wavelength Region.
George M. Hale,Marvin R. Querry +1 more
TL;DR: Extinction coefficients k(lambda) for water at 25 degrees C were determined through a broad spectral region by manually smoothing a point by point graph of k( lambda) vs wavelength lambda that was plotted for data obtained from a review of the scientific literature on the optical constants of water.
BookDOI
Optical-Thermal Response of Laser-Irradiated Tissue
TL;DR: Welch et al. as discussed by the authors proposed a Monte Carlo Modeling of Light Transport in Tissue S.C. van Gemert, A.J. van Leeuwen, et al., and C.C., Svaasand.
Journal ArticleDOI
PhotochemCAD‡: A Computer‐Aided Design and Research Tool in Photochemistry
TL;DR: In this article, a database of absorption and fluorescence spectra, including molar absorption coefficients, was compiled for 125 photochemically relevant compounds and an accompanying program enables calculation of oscillator strengths, natural radiative lifetimes, transition dipole moments, Forster energy-transfer rates, multicomponent analysis, simulations of fluorescence spectrum upon energy transfer among linear arrays of pigments, calculations of blackbody radiator curves at different temperatures and Lorentzian and Gaussian peak distributions.
Journal ArticleDOI
Near-infrared optical properties of ex vivo human skin and subcutaneous tissues measured using the Monte Carlo inversion technique
TL;DR: The absorption and transport scattering coefficients of c Caucasian and negroid dermis, subdermal fat and muscle have been measured for all wavelengths between 620 and 1000 nm and the optical properties of caucasian dermis were found to be approximately twice those of the underlying fat layer.
Journal ArticleDOI
Spectroscopic optical coherence tomography.
Uwe Morgner,Wolfgang Drexler,Franz X. Kärtner,Xingde Li,Costas Pitris,Erich P. Ippen,James G. Fujimoto +6 more
TL;DR: Spectroscopic optical coherence tomography (OCT) as discussed by the authors is an extension of conventional OCT for performing cross-sectional tomographic and spectroscopic imaging, which allows the spectrum of backscattered light to be measured over the entire available optical bandwidth simultaneously in a single measurement.