Orthobiologics with phytobioactive cues: A paradigm in bone regeneration.
TLDR
A bird's eye view of different strategies used in bone healing, mechanisms involved and future direction of advancements using phytobioactives and orthobiologics is provided.About:
This article is published in Biomedicine & Pharmacotherapy.The article was published on 2020-09-18 and is currently open access. It has received 13 citations till now. The article focuses on the topics: Bone regeneration & Bone healing.read more
Citations
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The Review of Natural Products
TL;DR: The Review of Natural Products provides detailed information about natural products, including their botany, history, chemistry, pharmacology, medicinal uses, toxicology, and patient information, which also includes significantly documented drug interactions.
M1 muscarinic receptor is a key target of neuroprotection, neuroregeneration and memory recovery by i-Extract from Withania somnifera
Arpita Konar,Richa Gupta,Rajendra K. Shukla,Bryan Maloney,Vinay K. Khanna,Renu Wadhwa,Debomoy K. Lahiri,Mahendra K. Thakur +7 more
TL;DR: This article showed that muscarinic subtype acetylcholine receptors that regulate memory processes are a key target of Ashwagandha extract in Alzheimer's disease and showed that i-extract stimulated an increase in dendrite growth markers, including kallikrein 8 and MAP2.
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Stem cell-derived exosomes in bone healing: focusing on their role in angiogenesis.
Daniyal Irfan,Irfan Ahmad,Indrajit Patra,Ria Margiana,Mokhidil Tursunalievna Rasulova,Rathish Kumar Sivaraman,Mahmoud Kandeel,Hawraa Jabbar Mohammad,Zahraa Haleem Al-qaim,Mohammed Jawad,Yasser Fakri Mustafa,Mohammad Javed Ansari +11 more
TL;DR: In this paper , a review summarizes the effects of stem cell-derived exosomes on the repair of bone tissue, focusing on the angiogenesis process, and develops therapeutic strategies to promote angiogenicity will facilitate bone regeneration and healing.
µCT analysis reveals that Cissus quadrangularis L. stem and Trigonella foenum-graecum L. seed extracts prevent diabetic osteopathy
TL;DR: CQ and TFG combination therapy showed a marked improvement in bone microarchitecture and can be given together as a potential alternative medicine to insulin for prevention of type I diabetes induced osteopathy.
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Pro-Osteogenic Properties of Violina pumpkin (Cucurbita moschata) Leaf Extracts: Data from In Vitro Human Primary Cell Cultures.
Elisabetta Lambertini,Letizia Penolazzi,Giulia Pellielo,Caterina Pipino,Assunta Pandolfi,Serena Fiorito,Francesco Epifano,Salvatore Genovese,Roberta Piva +8 more
TL;DR: In this paper, the potential pro-osteogenic effects of hexane, acetone and methanol extracts of the leaves of Cucurbita moschata, a very popular pumpkin cultivar in Western countries, were investigated for the first time.
References
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Phytochemicals: Extraction, Isolation, and Identification of Bioactive Compounds from Plant Extracts
TL;DR: There are concerns about using synthetic phenolic antioxidants as food additives because of the reported negative effects on human health, so a replacement of these synthetics by antioxidant extractions from various foods has been proposed.