Journal ArticleDOI
Papillary and follicular thyroid carcinoma.
TLDR
Treatment of recurrences is based mainly on surgery and 131I treatment, and the recent availability of recombinant human thyroid stimulating hormone has greatly improved the quality of the patient's life during follow-up.Abstract:
Papillary and follicular thyroid carcinomas are among the most curable of all cancers. However, some patients are at high risk of recurrence or even death from their cancer. Most of these patients can be identified at the time of diagnosis using well-established prognostic indicators. The extent of initial treatment and follow-up should therefore be individualized. The early discovery of persistent and recurrent disease is based on the combined use of serum thyroglobulin determination and of total body scanning with 131I. The recent availability of recombinant human thyroid stimulating hormone has greatly improved the quality of the patient's life during follow-up. Treatment of recurrences is based mainly on surgery and 131I treatment.read more
Citations
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Journal ArticleDOI
Current Approaches to Primary Therapy for Papillary and Follicular Thyroid Cancer
TL;DR: The approach to treatment of papillary and follicular cancer is usually very similar, and DTC is more likely to be completely resected and ablated with iodine-131 (I), an approach that has become more popular in the past several decades when discovered at an early stage.
Journal ArticleDOI
Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound and color-Doppler features.
Enrico Papini,Rinaldo Guglielmi,Antonio Bianchini,Anna Crescenzi,Silvia Taccogna,Francesco Nardi,Claudio Panunzi,R. Rinaldi,Vincenzo Toscano,Claudio Maurizio Pacella +9 more
TL;DR: The aim of the study was to correlate the sonographic and color-Doppler findings with the results of US-guided fine needle aspiration biopsy and of pathologic staging of resected carcinomas to establish the relative importance of US features as risk factors of malignancy and a cost-effective management of nonpalpable thyroid nodules.
Journal ArticleDOI
Guidelines for the management of thyroid cancer
Petros Perros,Kristien Boelaert,Steve Colley,Carol Evans,Rhordi M Evans,Georgina Gerrard Ba,Jackie Gilbert,Barney Harrison,Sarah J. Johnson,T. Giles,Laura Moss,Val Lewington,Kate Newbold,Judith Taylor,Rajesh V. Thakker,John Watkinson,Graham R. Williams +16 more
Journal ArticleDOI
The sodium/iodide Symporter (NIS): characterization, regulation, and medical significance.
Orsolya Dohán,Antonio De la Vieja,Viktoriya Paroder,Claudia A. Riedel,Mona Artani,Mia D. Reed,Christopher S. Ginter,Nancy Carrasco +7 more
TL;DR: The discovery of endogenous NIS expression in more than 80% of human breast cancer samples has raised the possibility that radioiodide may be a valuable novel tool in breast cancer diagnosis and treatment.
Journal ArticleDOI
American Association of Clinical Endocrinologists and Associazione Medici Endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nodules.
Hossein Gharib,Enrico Papini,Roberto Valcavi,H. Jack Baskin,Anna Crescenzi,Massimo E. Dottorini,Daniel S. Duick,Rinaldo Guglielmi,Carlos R. Hamilton,Martha A. Zeiger,Michele Zini,Elise M. Brett,Pauline M. Camacho,Samuel Dagogo-Jack,Vivian Fonseca,Robert F. Gagel,J. Michael Gonzalez-Campoy,Yehuda Handelsman,R. Mack Harrell,Romesh Khardori,Marc J. Laufgraben,Philip T. Levy,Virginia A. LiVolsi,Jeffrey I. Mechanick,A. Ola Odugbesan,Fernando Ovalle,Steven M. Petak,S. Sethu K. Reddy,Herbert I. Rettinger,Victor L. Roberts,Talla P. Shankar,Joseph J. Torre,Dace L. Trence,Roy E. Weiss,Milton K. Wong +34 more
TL;DR: These guidelines are thorough and practical, and they offer reasoned and balanced recommendations based on the best available evidence to clinical endocrinologists, endocrine surgeons, pediatricians, and internists whose practices include management of patients with thyroid disorders.
References
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Book
Cancer Incidence in Five Continents
Freddie Bray,J. Ferlay,Mathieu Laversanne,David H. Brewster,C. Gombe Mbalawa,B. Kohler,Marion Piñeros,Eva Steliarova-Foucher,Rajaraman Swaminathan,Sebastien Antoni,Isabelle Soerjomataram,David Forman +11 more
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Journal ArticleDOI
Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer.
TL;DR: Following 131I therapy, whether given for thyroid remnant ablation or cancer therapy, recurrence and the likelihood of cancer death were reduced by at least half, despite the existence of more adverse prognostic factors in patients given 131I.
Journal ArticleDOI
Management of a Solitary Thyroid Nodule
TL;DR: This review describes a strategy for the treatment of clinically euthyroid patients who have a solitary thyroid nodule that prevents unnecessary testing while identifying the few patients who require therapy.
Journal ArticleDOI
Thyroid Cancer after Exposure to External Radiation: A Pooled Analysis of Seven Studies
Elaine Ron,Jay H. Lubin,Roy E. Shore,Kiyohiko Mabuchi,Baruch Modan,Linda M. Pottern,Arthur B. Schneider,Margaret A. Tucker,John D. Boice +8 more
TL;DR: Based on limited data, there was a suggestion that spreading dose over time (from a few days to > 1 year) may lower risk, possibly due to the opportunity for cellular repair mechanisms to operate.
Journal ArticleDOI
Predicting outcome in papillary thyroid carcinoma: Development of a reliable prognostic scoring system in a cohort of 1779 patients surgically treated at one institution during 1940 through 1989
TL;DR: A reliable prognostic scoring system for predicting PTC mortality rates with 15 candidate variables that included completeness of primary tumor resection but excluded histologic grade and DNA ploidy is attempted.