Parkinson’s disease with camptocormia
Frédéric Bloch,J. L. Houeto,S. Tezenas du Montcel,Fabrice Bonneville,Fabien Etchepare,M.-L. Welter,Sophie Rivaud-Péchoux,Valérie Hahn-Barma,Thierry Maisonobe,C. Béhar,J. Y. Lazennec,Ewa Kurys,Isabelle Arnulf,Anne-Marie Bonnet,Yves Agid +14 more
TLDR
Patients with camptocormia were characterised by prominent levodopa-unresponsive axial symptoms (ie, axial rigidity, gait disorder and postural instability), along with a tendency for greater error in the antisaccade paradigm, and it is suggested that the salient features of parkinsonism observed in patients with camps are likely to represent a specific form of Parkinson’s disease.Abstract:
Background: Camptocormia is defined as an abnormal flexion of the trunk that appears when standing or walking and disappears in the supine position. The origin of the disorder is unknown, but it is usually attributed either to a primary or a secondary paravertebral muscle myopathy or a motor neurone disorder. Camptocormia is also observed in a minority of patients with parkinsonism. Objective: To characterise the clinical and electrophysiological features of camptocormia and parkinsonian symptoms in patients with Parkinson’s disease and camptocormia compared with patients with Parkinson’s disease without camptocormia. Methods: Patients with parkinsonism and camptocormia (excluding patients with multiple system atrophy) prospectively underwent a multidisciplinary clinical (neurological, neuropsychological, psychological, rheumatological) and neurophysiological (electromyogram, ocular movement recording) examination and were compared with age-matched patients with Parkinson’s disease without camptocormia. Results: The camptocormia developed after 8.5 (SD 5.3) years of parkinsonism, responded poorly to levodopa treatment (20%) and displayed features consistent with axial dystonia. Patients with camptocormia were characterised by prominent levodopa-unresponsive axial symptoms (ie, axial rigidity, gait disorder and postural instability), along with a tendency for greater error in the antisaccade paradigm. Conclusion: We suggest that (1) the salient features of parkinsonism observed in patients with camptocormia are likely to represent a specific form of Parkinson’s disease and camptocormia is an axial dystonia and (2) both camptocormia and parkinsonism in these patients might result from additional, non-dopaminergic neuronal dysfunction in the basal ganglia.read more
Citations
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Clinical correlates of anterior and lateral flexion of the thoracolumbar spine and dropped head in patients with Parkinson’s disease
Kenichi Kashihara,Takaki Imamura +1 more
TL;DR: Postural disorders are frequent complications in PD patients and their severity increases with disease progression, and advancing age and disease severity may be the major risks for developing postural disorders.
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Thoracolumbar spinal fixation for camptocormia in Parkinson’s disease
TL;DR: Although this case demonstrates that spinal fixation surgery can be successful, it should probably only be offered after subthalamic nucleus deep brain stimulation has been unsuccessful, or for well motivated patients who express a strong wish for this major reconstructive surgery.
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Bent spine syndrome (camptocormia): a retrospective study of 63 patients.
Michel Laroche,Pascal Cintas +1 more
TL;DR: In this case-series, delayed-onset paraspinal myopathy accounted for 64% of cases of Bent spine syndrome, and the most informative investigation was CT, which showed a patchy decrease inParaspinal muscle density.
Journal ArticleDOI
Camptocormia in Parkinson’s disease: new insights
R Djaldetti,E Melamed +1 more
TL;DR: Of the several axial deformities, stooped posture is the most common postural abnormality and is now accepted also as one of the axial features of Parkinson’s disease.
Journal ArticleDOI
Immediate effect of spinal magnetic stimulation on camptocormia in Parkinson's disease.
Yoshiharu Arii,Yuki Sawada,Kazuyuki Kawamura,Sayaka Miyake,Yasuo Taichi,Yuishin Izumi,Yukiko Kuroda,Toshio Inui,Ryuji Kaji,Takao Mitsui +9 more
TL;DR: Although the effect was transient, this successful trial justifies further studies to test if repeated rTSMS treatments can induce longer term improvements in camptocormia associated with PD.
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