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Open AccessJournal ArticleDOI

Perinatal mental illness: Definition, description and aetiology

TLDR
Perinatal mental illness is a significant complication of pregnancy and the postpartum period and early detection and effective management of perinatal psychiatric disorders are critical for the welfare of women and their offspring.
Abstract
Perinatal mental illness is a significant complication of pregnancy and the postpartum period. These disorders include depression, anxiety disorders, and postpartum psychosis, which usually manifests as bipolar disorder. Perinatal depression and anxiety are common, with prevalence rates for major and minor depression up to almost 20% during pregnancy and the first 3 months postpartum. Postpartum blues are a common but lesser manifestation of postpartum affective disturbance. Perinatal psychiatric disorders impair a woman's function and are associated with suboptimal development of her offspring. Risk factors include past history of depression, anxiety, or bipolar disorder, as well psychosocial factors, such as ongoing conflict with the partner, poor social support, and ongoing stressful life events. Early symptoms of depression, anxiety, and mania can be detected through screening in pregnancy and the postpartum period. Early detection and effective management of perinatal psychiatric disorders are critical for the welfare of women and their offspring.

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Citations
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Journal ArticleDOI

Consequences of maternal postpartum depression: a systematic review of maternal and infant outcomes

TL;DR: The results suggest that postpartum depression creates an environment that is not conducive to the personal development of mothers or the optimal development of a child, and it seems important to detect and treat depression during the postnatal period as early as possible to avoid harmful consequences.
Journal ArticleDOI

Biological and Psychosocial Predictors of Postpartum Depression: Systematic Review and Call for Integration

TL;DR: A systematic review of research published from 2000 through 2013 on biological and psychosocial factors associated with PPD and postpartum depressive symptoms found the strongest PPD risk predictors are hypothalamic-pituitary-adrenal dysregulation, inflammatory processes, and genetic vulnerabilities.
Journal ArticleDOI

Depression during Pregnancy.

TL;DR: This review describes best practices for the management of depression in pregnancy and provides suggestions for future research.
Journal ArticleDOI

Sex differences in depression: Insights from clinical and preclinical studies.

TL;DR: Evidence is provided to support the notion that differences in depression between men and women span multiple facets of the disease, including epidemiology, symptomology, treatment, and pathophysiology, and a more systematic consideration of biological sex as a variable in depression research will be critical in the discovery and development of pharmacotherapies that are efficacious for both men andWomen.
References
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Journal ArticleDOI

Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale.

TL;DR: The development of a 10-item self-report scale (EPDS) to screen for Postnatal Depression in the community was found to have satisfactory sensitivity and specficity, and was also sensitive to change in the severity of depression over time.
Journal ArticleDOI

Rates and risk of postpartum depression—a meta-analysis

TL;DR: The average prevalence rate of non-psychotic postpartum depression based on the results of a large number of studies is 13% as discussed by the authors, and the average prevalence estimates are affected by the nature of the assessment method.
Journal ArticleDOI

Perinatal depression: a systematic review of prevalence and incidence.

TL;DR: To better delineate periods of peak prevalence and incidence for perinatal depression and identify high risk subpopulations, studies with larger and more representative samples are needed.
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Lifetime and 12-Month Prevalence of Bipolar Spectrum Disorder in the National Comorbidity Survey Replication

TL;DR: This study presents the first prevalence estimates of the BPD spectrum in a probability sample of the United States, and finds subthreshold BPD is common, clinically significant, and underdetected in treatment settings.
Journal ArticleDOI

Predictors of postpartum depression: an update.

TL;DR: Results confirmed findings of an earlier meta-analysis and in addition revealed four new predictors of postpartum depression: self-esteem, marital status, socioeconomic status, and unplanned/unwanted pregnancy.
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