Journal ArticleDOI
Phase Transitions in Phospholipid Vesicles: Excited State Prototropism of 1-Naphthol as a Novel Probe Concept
J. Sujatha,Ashok Kumar Mishra +1 more
TLDR
In this paper, 1-Naphthol (1-ROH) undergoes partial dissociation in the excited state in liposome membrane, giving two fluorescence peaks as against a single peak in water.Abstract:
1-Naphthol (1-ROH), an excited state acid, undergoes partial dissociation in the excited state in liposome membrane, giving two fluorescence peaks as against a single peak in water. 1-Naphthol distributes between two different sites of different excited state reactivity in liposome, and the relative population in the two different sites changes with any perturbations in the membrane fluidity. This property is made use of in studying the thermotropic phase changes and cholesterol effect on the transition temperature of DMPC (dimyristoylphosphatidylcholine) and DPPC (dipalmitoylphosphatidylchloline) liposomes. The change in the permeability of the membrane due to thermotropic phase changes and the phase transition temperature of liposomes could be easily monitored by fluorescence spectroscopy from a conspicuous change in the emission of the neutral form of 1-naphthol. The applicability of 1-naphthol probe to mixed lipid sytems has also been examined.read more
Citations
More filters
Journal ArticleDOI
Modulated photophysics of an ESIPT probe 1-hydroxy-2-naphthaldehyde within motionally restricted environments of liposome membranes having varying surface charges.
Bijan Kumar Paul,Nikhil Guchhait +1 more
TL;DR: Modifications on the emission profile of HN12 in terms of remarkable emission intensity enhancement coupled with a hypsochromic shift induced by the presence of DMPC and DMPG membranes have been interpreted to be vivid manifestations of the interactions between the two partners.
Journal ArticleDOI
Inclusion of a photosensitizer in liposomes formed by DMPC/gemini surfactant: correlation between physicochemical and biological features of the complexes.
Cecilia Bombelli,Giulio Caracciolo,Pietro Di Profio,Marco Diociaiuti,Paola Luciani,Giovanna Mancini,Claudia Mazzuca,Manuela Marra,Agnese Molinari,Donato Monti,Laura Toccacieli,Mariano Venanzi +11 more
TL;DR: A correlation between the physicochemical features of formulations and their efficiency as photosensitizers vector was found.
Journal ArticleDOI
Excited-state proton transfer of 1-naphthol in micelles
TL;DR: In this article, the fast deprotonation of 1-naphthol, which occurs in 35 ps in aqueous solution, was studied in neutral (triton X 100, reduced, TX-100R), cationic (cetyl trimethylammonium bromide, CTAB), and anioni...
Journal ArticleDOI
Photophysical Behavior of Fisetin in Dimyristoylphosphatidylcholine Liposome Membrane
TL;DR: A detailed photophysical study of the plant flavonoid fisetin in a dimyristoylphosphatidylcholine (DMPC) bilayer membrane has been carried out as mentioned in this paper.
Journal ArticleDOI
Effect of submicellar concentrations of conjugated and unconjugated bile salts on the lipid bilayer membrane.
TL;DR: Steady-state and time-resolved fluorescence of the two excited-state prototropic forms of 1-naphthol indicate that submicellar bile salt concentration induces hydration of the lipid bilayer membrane into the core region.
References
More filters
Journal ArticleDOI
Phosphatidylcholine vesicles. Formation and physical characteristics
Journal ArticleDOI
Physical studies of phospholipids. VI. Thermotropic and lyotropic mesomorphism of some 1,2-diacyl-phosphatidylcholines (lecithins)
TL;DR: The thermotropic and lyotropic mesomorphism of saturated 1,2-diacyl-L-phosphatidylcholines (lecithins) has been studied by light microscopy, differential thermal analysis, X-ray diffraction, infrared and nuclear magnetic resonance spectroscopy.
Journal ArticleDOI
Dynamics of lipids in membranes: Heterogeneity and the role of cholesterol.
Eric Oldfield,D. Chapman +1 more
TL;DR: Some recent advances in understanding of the molecular dynamics of lipids in both natural and model membrane systems, which have been obtained using the techniques of differential scanning calorimetry, nuclear magnetic resonance, electron spin resonance, X-ray diffraction, infra-red and Raman spectroscopy are summarized.
Journal ArticleDOI
Excited-state proton transfer reactions I. Fundamentals and intermolecular reactions
TL;DR: Theoretical models that have been proposed and applied to proton transfer reactions are reviewed in this paper, where simple models, like the Eigen model, Marcus theory and the intersecting state model, are applied to excited-state intermolecular proton transfers.
Journal ArticleDOI
High-sensitivity scanning calorimetric study of mixtures of cholesterol with dimyristoyl- and dipalmitoylphosphatidylcholines.
TL;DR: A highly sensitive and stable scanning microcalorimeter is employed in a reinvestigation of the effect of cholesterol on multilamellar suspensions of dimyristoylphosphatidylcholine and DPPC, suggesting the coexistence of two immiscible solid phases.
Related Papers (5)
Effect of ionic and neutral surfactants on the properties of phospholipid vesicles: investigation using fluorescent probes
J. Sujatha,Ashok Kumar Mishra +1 more