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Journal ArticleDOI

Physiological effects of nanoparticles on fish: A comparison of nanometals versus metal ions

Benjamin J. Shaw, +1 more
- 01 Aug 2011 - 
- Vol. 37, Iss: 6, pp 1083-1097
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TLDR
It is concluded that nanometals do have adverse physiological effects on fish, and the hazard for some metal NPs will be different to the traditional dissolved forms of metals.
About
This article is published in Environment International.The article was published on 2011-08-01. It has received 359 citations till now. The article focuses on the topics: Metal toxicity.

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Citations
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Immobilized silver nanoparticles enhance contact killing and show highest efficacy: elucidation of the mechanism of bactericidal action of silver

TL;DR: In this study, AgNPs were immobilized on an amine-functionalized silica surface and their bactericidal activity was studied concurrently with the silver release profile over time, concluding that contact killing is the predominant bactericidal mechanism and surface immobilized nanoparticles show greater efficacy than colloidal AgNPS, as well as a higher concentration of silver ions in solution.
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The antibacterial effects of silver, titanium dioxide and silica dioxide nanoparticles compared to the dental disinfectant chlorhexidine on Streptococcus mutans using a suite of bioassays.

TL;DR: Metal-containing nanomaterials have the potential to be used in dentistry for infection control, but little is known about their antibacterial properties, and Ag NPs were the best disinfectant and performed better than chlorhexidine.
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Zebrafish as a model system to study toxicology.

TL;DR: The authors address the new direction of developing high‐throughput detection of genetically modified transparent zebrafish to open a new window for monitoring environmental pollutants.
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Nanoparticle toxicity by the gastrointestinal route: evidence and knowledge gaps.

TL;DR: Focus was placed on three categories of nanomaterials: nanometals and metal oxides, carbon-based nanoparticles, and polymer/dendrimers with emphasis on those particles of greatest relevance to gastrointestinal exposures.
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Impacts of metal and metal oxide nanoparticles on marine organisms.

TL;DR: In marine systems, Me(O)NPs can absorb to micro-organisms with potential for trophic transfer following consumption, and their likely fate here is sedimentation following hetero-aggregation with natural organic matter and/or free anions, putting benthic, sediment-dwelling and filter feeding organisms most at risk.
References
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Journal ArticleDOI

Induction of oxidative stress and apoptosis by silver nanoparticles in the liver of adult zebrafish.

TL;DR: The hepatotoxicity of AgNPs was assessed in the liver of adult zebrafish, and data suggest that oxidative stress and apoptosis are associated with AgNP toxicity in the Liver of adultZebrafish.
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Acidification and Toxicity of Metals to Aquatic Biota

TL;DR: A pH-dependent biological response is documented over a realistic range of H+ and metal concealing surfaces, and supporting experimental evidence exists for four metals.
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Nutritive metal uptake in teleost fish.

TL;DR: This review will assess physiological, pharmacological and recent molecular evidence to outline possible uptake pathways in the gills and intestine of teleost fish involved in the acquisition of three of the most abundant transition metals necessary for life; iron, copper, and zinc.
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Hydroxyl radicals (*OH) are associated with titanium dioxide (TiO(2)) nanoparticle-induced cytotoxicity and oxidative DNA damage in fish cells.

TL;DR: Investigations aimed to evaluate the potential cytotoxic and genotoxic effects of TiO(2) nanoparticles on goldfish skin cells (GFSk-S1), either alone or in combination with UVA revealed that the observed toxic effects of nanoparticulate TiO (2) were most likely due to hydroxyl radical (OH) formation.
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Comparison of Molecular and Histological Changes in Zebrafish Gills Exposed to Metallic Nanoparticles

TL;DR: Global gene expression analysis demonstrates that the exposure to each nanometal or soluble metal produces a distinct gene expression profile at both 24 and 48 h, suggesting that each exposure is producing biological response by a different mechanism.
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