Open AccessJournal Article
Phytochemical Constituents of Bistorta manshuriensis
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TLDR
In this paper, Bistorta manshuriensis was used to extract MeOH from the aerial parts of the aerial part of the plant and two cerebrosides, two lactams, six phenolic compounds and seven flavonoids were identified.Abstract:
Phytochemical investigation of the MeOH extract of the aerial parts of Bistorta manshuriensis resulted in the isolation of two cerebrosides, two lactams, six phenolic compounds and seven flavonoids Their chemical structures were characterized by spectroscopic methods to be pinelloside (1), soyacerebroside I (2), pterolactam (3), 5-hydroxypyrrolidine-2-one (4), vanillic acid (5), caffeic acid methyl ester (6), protocatechuic acid (7), caffeic acid (8), 3,5-di-O-caffeoyl quinic acid methyl ester (9), chlorogenic acid methyl ester (10), avicularin (11), afzelin (12), quercetin (13), isoorientin (14), quercetin 3-O--D-glucoside (15), quercitrin (16), and luteolin (17) The isolated compounds (1 - 4, 7, 12, 14) were isolated for the first time from this plant source and the compounds 1 - 4, 9 and 10 were first reported from the genus Bistorta Compound 17 exhibited moderate cytotoxicity and compound 6 exhibited weak cytotoxicity against four human cancer cell lines in vitro using an SRB bioassayread more
Citations
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Anti-inflammatory activity of caffeic acid derivatives isolated from the roots of Salvia miltiorrhiza Bunge.
TL;DR: Ten caffeic acid derivatives were isolated from the roots of Salvia miltiorrhiza by using various chromatographic methods and their chemical structures were spectroscopically elucidated and evaluated for their inhibitory effect on NO production.
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Phytochemical Analysis and Antimicrobial Activity of Myrcia tomentosa (Aubl.) DC. Leaves
Fabyola Amaral da Silva Sá,Joelma Abadia Marciano de Paula,Pierre Alexandre dos Santos,Leandra de Almeida Ribeiro Oliveira,Gerlon de Almeida Ribeiro Oliveira,Luciano M. Lião,José Realino de Paula,Maria do Rosário Rodrigues Silva +7 more
TL;DR: The MIC values suggest potential activity of this plant species against yeast, and the isolation and structural elucidation of compounds from the leaves of Myrcia tomentosa (Aubl.) DC.
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Effect of the Polyphenol Rich Ethyl Acetate Fraction from the Leaves of Lycium chinenseMill. on Oxidative Stress, Dyslipidemia, and Diabetes Mellitus in Streptozotocin-Nicotinamide Induced Diabetic Rats.
TL;DR: The present study has revealed that L. chinenseMill possess anti‐hyperglycemic and anti-hyperlipidemic properties which is mediated through modulation of oxidative stress and polyphenolics might be responsible for the action.
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Evaluation of the Antidiabetic Activity and Chemical Composition of Geranium collinum Root Extracts-Computational and Experimental Investigations.
Sodik Numonov,Salamet Edirs,Khayrulla Bobakulov,Muhammad Nasimullah Qureshi,Khurshed Bozorov,Khurshed Bozorov,Farukh Sharopov,Farukh Sharopov,William N. Setzer,Haiqing Zhao,Maidina Habasi,Mizhgona Sharofova,Haji Akber Aisa +12 more
TL;DR: The experimental results suggest that the biological activity of G. collinum is related to its polyphenol contents, and the potent antidiabetic activity of the 50% aqueous-ethanolic extract from G.collinum shows promise for its future application in medicine.
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Study of the antioxidant activity of Thymus sibthorpii Bentham (Lamiaceae)
Christos Kontogiorgis,Maria Ntella,Lina Mpompou,Fotini Karallaki,Papadopoulos Athanasios,Dimitra Hadjipavlou-Litina,Diamanto Lazari +6 more
TL;DR: The antioxidant results of the extracts are discussed in terms of their constitution in phenolic compounds, which were determined following the Folin–Ciocalteu method.
References
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New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening
Philip Skehan,Ritsa Storeng,Dominic A. Scudiero,Anne Monks,James B. McMahon,David T. Vistica,Jonathan T. Warren,Heidi R. Bokesch,Susan Kenney,Michael R. Boyd +9 more
TL;DR: The SRB assay provides a sensitive measure of drug-induced cytotoxicity, is useful in quantitating clonogenicity, and is well suited to high-volume, automated drug screening.
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Carbon-13 NMR studies of flavonoids. III. Naturally occurring flavonoid glycosides and their acylated derivatives
TL;DR: In this article, 13 C NMR spectra for a variety of flavonoid glycosidcs are presented and analyzed, and evidence is presented which demonstrates that 13 C nMR spectroscopy is a valuable technique for distinguishing the sites of methylation, glycosylation and acylation in glycoiides.
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Carbon-13 NMR studies of flavonoids—I
B. Ternai,K.R. Markham +1 more
TL;DR: In this article, the C-NMR spectra of hydroxylated flavones and flavonols are presented for the first time and the accepted substitution additivity rules have been shown to hold for these compounds except in cases where structural modifications involve the C 3, 4 and 5 positions.
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High resolution1H- and13C-N.M.R spectra ofD-glucopyranose, 2-acetamido-2-deoxy-D-glucopyranose, and related compounds in aqueous media
TL;DR: In this paper, the p.m.r spectra of D -glucopyranose and 2-acetamido-2-deoxy derivatives in D 2 O at 25° have been completely interpreted.
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Biological and Pharmacological Activities and Further Constituents of Hyptis verticillata
TL;DR: The essential oil, (R)-5-hydroxypyrrolidin-2-one, as well as the previously isolated rosmarinic acid and dehydropodophyllotoxine contributed to the antibacterial effects of H. verticillata.